Showing 181-200 of 753 for: Cochrane Systematic Reviews > Pharmacotherapeutics
- Calcium and vitamin D for corticosteroid-induced osteoporosis
Cochrane Systematic Reviews, 24-May-2010
Osteoporosis and subsequent fracture are a major cause of morbidity and mortality. It is defined by low bone mass, and has many etiologies with different patterns of bone loss. Corticosteroid therapy is a contributor to the development of osteoporosis. St
- Calcium channel blockers for acute traumatic brain injury
Cochrane Systematic Reviews, 12-Aug-2008
Acute traumatic brain injury is a major cause of death and disability. Calcium channel blockers (calcium antagonists) have been used in an attempt to prevent cerebral vasospasm after injury, maintain blood flow to the brain, and so prevent further damage.
- Calcium channel blockers for inhibiting preterm labour and birth
Cochrane Systematic Reviews, 2-Jul-2014
Preterm birth is a major contributor to perinatal mortality and morbidity, affecting around 9% of births in high-income countries and an estimated 13% of births in low- and middle-income countries. Tocolytics are drugs used to suppress uterine contraction
- Calcium channel blockers for neuroleptic-induced tardive dyskinesia
Cochrane Systematic Reviews, 1-May-2013
Schizophrenia and related disorders affect a sizable proportion of any population. Neuroleptic (antipsychotic) medications are the primary treatment for these disorders. Neuroleptic medications are associated with a variety of side effects including tardi
- Calcium channel blockers for potential impaired fetal growth
Cochrane Systematic Reviews, 2-Aug-2009
Calcium channel blockers may increase the blood flow to the fetus or may improve fetal-placental cellular energy generation. This could enhance fetal growth.
- Calcium channel blockers for preventing acute tubular necrosis in kidney transplant recipients
Cochrane Systematic Reviews, 21-Sep-2008
The incidence of delayed graft function in cadaveric grafts has increased over the last few years due in part to the large demand for cadaveric kidneys necessitating the use of kidneys from marginal donors. Calcium channel blockers have the potential to r
- Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Cochrane Systematic Reviews, 19-Jun-2014
Pre-eclampsia and eclampsia are common causes of serious morbidity and death. Calcium supplementation may reduce the risk of pre-eclampsia, and may help to prevent preterm birth.
- Calcium supplementation for improving bone mineral density in children
Cochrane Systematic Reviews, 16-Mar-2010
Clinical trials have shown that calcium supplementation in children can increase bone mineral density (BMD) although this effect may not be maintained. There has been no quantitative systematic review of this intervention.
- Calcium supplementation for the management of primary hypertension in adults
Cochrane Systematic Reviews, 12-Nov-2008
Metabolic studies suggest calcium may have a role in the regulation of blood pressure. Some epidemiological studies reported people with a higher intake of calcium tend to have lower blood pressure. Previous systematic reviews and meta-analyses reached co
- Carbamazepine for chronic neuropathic pain and fibromyalgia in adults
Cochrane Systematic Reviews, 10-Apr-2014
This is an update of a Cochrane review entitled 'Carbamazepine for acute and chronic pain in adults' published in Issue 1, 2011. Some antiepileptic medicines have a place in the treatment of neuropathic pain (pain due to nerve damage). This updated review
- Carbamazepine for schizophrenia
Cochrane Systematic Reviews, 1-Apr-2014
Many people with schizophrenia do not achieve a satisfactory treatment response with just antipsychotic drug treatment and various adjunct medications are used to promote additional response. The antiepileptic carbamazepine is one such drug.
- Cardioselective beta-blockers for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 23-Nov-2010
Beta-blocker therapy has a proven mortality benefit in patients with hypertension, heart failure and coronary artery disease, as well as during the perioperative period. These drugs have traditionally been considered contraindicated in patients with chron
- Cardioselective beta-blockers for reversible airway disease
Cochrane Systematic Reviews, 29-Sep-2011
Beta-blocker therapy has mortality benefit in patients with hypertension, heart failure and coronary artery disease, as well as during the perioperative period. These drugs have traditionally been considered contraindicated in patients with reversible air
- Celecoxib for rheumatoid arthritis
Cochrane Systematic Reviews, 9-Sep-2008
Rheumatoid arthritis (RA) is a systemic auto-immune disorder, involving persistent joint inflammation. NSAIDs are used to control the symptoms of RA, but are associated with significant gastro-intestinal toxicity, including a risk of potentially life thre
- Central action beta-blockers versus placebo for neuroleptic-induced acute akathisia
Cochrane Systematic Reviews, 13-Apr-2010
Neuroleptic-induced akathisia is a common, distressing early-onset adverse effect of neuroleptic drugs. It has been associated with poor treatment compliance and an increased risk of relapse.
- Central venous access sites for the prevention of venous thrombosis, stenosis and infection
Cochrane Systematic Reviews, 3-Feb-2012
Central venous access (CVA) is widely used. However, its thrombotic, stenotic and infectious complications can be life-threatening and involve high-cost therapy. Research revealed that the risk of catheter-related complications varied according to the sit
- Chemotherapy alone versus endocrine therapy alone for metastatic breast cancer
Cochrane Systematic Reviews, 24-May-2011
Both chemotherapy and endocrine therapy can be used as treatments for metastatic breast cancer.
- Chemotherapy for advanced ovarian cancer
Cochrane Systematic Reviews, 21-Feb-2011
Ovarian carcinoma is the seventh commonest female cancer worldwide and is responsible for the greatest number of deaths from gynaecological malignancy in Europe and North America. Although many studies have explored the use of chemotherapy in this disease
- Chemotherapy for high-grade glioma
Cochrane Systematic Reviews, 27-Mar-2014
Trials on the effect of systemic chemotherapy on survival and recurrence in adults with high-grade glioma have had inconclusive results. We undertook a systematic review and meta-analysis to assess the effects of such treatment on survival and recurrence.
- Chemotherapy for non-small cell lung cancer
Cochrane Systematic Reviews, 9-Mar-2015
The role of chemotherapy in the treatment of patients with non-small cell lung cancer was not clear. A systematic review and quantitative meta-analysis was therefore undertaken to evaluate the available evidence from all relevant randomised trials.