Showing 201-220 of 746 for: Cochrane Systematic Reviews > Pharmacotherapeutics 
- Ciclesonide versus other inhaled steroids for chronic asthma in children and adults
Cochrane Systematic Reviews, 29-Mar-2009
Inhaled corticosteroids (ICS) are an integral part of asthma management, and act as an anti-inflammatory agent in the airways of the lung. These agents confer both significant benefit in terms of symptom management and improvement in lung function, but ma
- Cisapride for Intestinal Constipation
Cochrane Systematic Reviews, 7-Dec-2010
Cisapride is a propulsive agent, withdrawn from most of the world's health institutes because of its recorded fatalities in addition to serious side effects such as severe arrhythmias. However it is widely available in third world countries and can be eas
- Citalopram versus other anti-depressive agents for depression
Cochrane Systematic Reviews, 12-Jun-2012
Recent US and UK clinical practice guidelines recommend that second-generation antidepressants should be considered amongst the best first-line options when drug therapy is indicated for a depressive episode. Systematic reviews have already highlighted so
- Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome
Cochrane Systematic Reviews, 15-Dec-2016
Subfertility due to anovulation is a common problem in women. First-line oral treatment is with antioestrogens such as clomiphene citrate, but resistance may be apparent with clomiphene. Alternative and adjunctive treatments have been used including tamox
- Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular events
Cochrane Systematic Reviews, 14-Dec-2017
Aspirin is the prophylactic antiplatelet drug of choice for people with cardiovascular disease. Adding a second antiplatelet drug to aspirin may produce additional benefit for people at high risk and people with established cardiovascular disease. This is
- Clotiapine for acute psychotic illnesses
Cochrane Systematic Reviews, 25-Jul-2012
Acute psychotic illnesses, especially when associated with agitated or violent behaviour, require urgent pharmacological tranquillisation or sedation. Clotiapine, a dibenzothiazepine neuroleptic, is being used for this purpose in several countries.
- Clozapine versus typical neuroleptic medication for schizophrenia
Cochrane Systematic Reviews, 21-Jan-2009
Long-term drug treatment of schizophrenia with typical antipsychotic drugs has limitations: 25 to 33% of sufferers have illnesses that are treatment resistant. Clozapine is an antipsychotic drug, which is claimed to have superior efficacy and to cause few
- Colchicine as an oral corticosteroid sparing agent for asthma
Cochrane Systematic Reviews, 21-Jul-2003
Oral corticosteroids are used as a treatment for asthma, but they are often associated with serious side effects. Colchicine is an anti-inflammatory, immuno modulating agent, which could potentially have a beneficial effect in the treatment of asthma as w
- Combination pharmacotherapy for the treatment of neuropathic pain in adults
Cochrane Systematic Reviews, 11-Jul-2012
Pharmacotherapy remains an important modality for the treatment of neuropathic pain. However, as monotherapy current drugs are associated with limited efficacy and dose-related side effects. Combining two or more different drugs may improve analgesic effi
- Combined corticosteroid and long-acting beta2-agonist in one inhaler versus inhaled corticosteroids alone for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 4-Jun-2014
Both long-acting beta2-agonists and inhaled corticosteroids have been recommended in guidelines for the treatment of chronic obstructive pulmonary disease (COPD). Their co-administration in a combined inhaler is intended to facilitate adherence to medicat
- Combined corticosteroid and long-acting beta2-agonist in one inhaler versus long-acting beta2-agonists for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 12-Apr-2013
Both inhaled steroids (ICS) and long-acting beta2-agonists (LABA) are used in the management of chronic obstructive pulmonary disease (COPD). This updated review compared compound LABA plus ICS therapy (LABA/ICS) with the LABA component drug given alone.
- Combined corticosteroid and long‐acting beta2‐agonist in one inhaler versus placebo for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 10-Nov-2013
Both long-acting beta2-agonists (LABA) and inhaled corticosteroids (ICS) have been recommended in guidelines for the treatment of chronic obstructive pulmonary disease (COPD). Their coadministration in a combination inhaler may facilitate adherence to med
- Combined psychotherapy plus antidepressants for panic disorder with or without agoraphobia
Cochrane Systematic Reviews, 31-Oct-2008
Panic disorder can be treated with pharmacotherapy, psychotherapy or in combination, but the relative merits of combined therapy have not been well established.
- Commercial versus home-made spacers in delivering bronchodilator therapy for acute therapy in children
Cochrane Systematic Reviews, 21-Aug-2017
Strong evidence supports the use of metered-dose inhalers combined with a spacer for delivering rapid-acting inhaled beta-2 agonists in the treatment of acute exacerbations of asthma in children. The high cost and lack of availability of commercially prod
- Computerized advice on drug dosage to improve prescribing practice
Cochrane Systematic Reviews, 7-Nov-2013
Maintaining therapeutic concentrations of drugs with a narrow therapeutic window is a complex task. Several computer systems have been designed to help doctors determine optimum drug dosage. Signi?cant improvements in health care could be achieved if comp
- Concomitant chemotherapy and radiation therapy for cancer of the uterine cervix
Cochrane Systematic Reviews, 20-Jul-2005
The National Cancer Institute (USA) alert in February 1999 stated that concomitant chemoradiotherapy should be considered for all patients with cervical cancer, based on evidence from five randomised controlled trials (RCTs).
- Continuous versus intermittent beta‐agonists for acute asthma
Cochrane Systematic Reviews, 20-Oct-2003
Patients with acute asthma treated in the emergency department are frequently treated with intermittent inhaled beta-agonists delivered by nebulisation. The use of continuous beta-agonist (CBA) via nebulisation in the emergency setting may offer additiona
- Corticosteroid injections for shoulder pain
Cochrane Systematic Reviews, 20-Jan-2003
While many treatments, including corticosteroid injections in and around the shoulder, are advocated to be of benefit for shoulder pain, few are of proven efficacy. This review of corticosteroid injections for shoulder pain is one in a series of reviews o
- Corticosteroids for acute bacterial meningitis
Cochrane Systematic Reviews, 12-Sep-2015
In experimental studies, the outcome of bacterial meningitis has been related to the severity of inflammation in the subarachnoid space. Corticosteroids reduce this inflammatory response.
- Corticosteroids for acute ischaemic stroke
Cochrane Systematic Reviews, 7-Sep-2011
The majority of strokes are due to cerebral infarction. Ischaemic cerebral tissue tends to develop cytotoxic oedema which, if the blood-brain barrier is disrupted, may be followed by vasogenic oedema. Large infarcts can develop life-threatening massive oe
