Showing 201-220 of 753 for: Cochrane Systematic Reviews > Pharmacotherapeutics 
- Chemotherapy versus best supportive care for extensive small cell lung cancer
Cochrane Systematic Reviews, 22-Nov-2013
Combination chemotherapy has been the mainstay of treatment for extensive stage small celI lung cancer (SCLC) over the last 30 years, even though it only gives a short prolongation in median survival time. The main goal for these patients should be pallia
- Chinese herbal medicine for schizophrenia
Cochrane Systematic Reviews, 15-Jan-2013
Traditional Chinese medicine (TCM) was the main form of treatment in China for psychiatric illnesses until the development of antipsychotic drugs in the 1950's. Antipsychotic drugs have become the primary intervention for schizophrenia, although herbal me
- Chinese herbal medicine in the treatment of ectopic pregnancy
Cochrane Systematic Reviews, 29-May-2011
Traditionally Chinese herbal medicine (CHM) has been used widely in Chinese hospitals to treat ectopic pregnancy. Many studies have been published supporting its use but the evidence has not been systematically reviewed. This is and update of the review p
- Chinese medicinal herbs for asymptomatic carriers of hepatitis B virus infection
Cochrane Systematic Reviews, 9-Oct-2008
About 350 million people are chronically infected carriers of hepatitis B virus and are at a higher risk of serious illness and death from cirrhosis of the liver and liver cancer. Chinese medicinal herbs have been used widely for more than 2000 years to t
- Chinese medicinal herbs for influenza
Cochrane Systematic Reviews, 19-Feb-2013
Influenza is a communicable acute respiratory infection which, during epidemics, can cause high morbidity and mortality rates. Traditional Chinese medicinal herbs, often administered following a particular Chinese medical theory, may be a potential treatm
- Ciclesonide versus other inhaled steroids for chronic asthma in children and adults
Cochrane Systematic Reviews, 29-Mar-2009
Inhaled corticosteroids (ICS) are an integral part of asthma management, and act as an anti-inflammatory agent in the airways of the lung. These agents confer both significant benefit in terms of symptom management and improvement in lung function, but ma
- Cisapride for Intestinal Constipation
Cochrane Systematic Reviews, 7-Dec-2010
Cisapride is a propulsive agent, withdrawn from most of the world's health institutes because of its recorded fatalities in addition to serious side effects such as severe arrhythmias. However it is widely available in third world countries and can be eas
- Citalopram versus other anti-depressive agents for depression
Cochrane Systematic Reviews, 12-Jun-2012
Recent US and UK clinical practice guidelines recommend that second-generation antidepressants should be considered amongst the best first-line options when drug therapy is indicated for a depressive episode. Systematic reviews have already highlighted so
- Clomiphene and anti-oestrogens for ovulation induction in PCOS
Cochrane Systematic Reviews, 9-Aug-2009
Subfertility due to anovulation is a common problem in women. First-line oral treatment is with anti-oestrogens, for example clomiphene citrate, but resistance (failure to ovulate) may be apparent with clomiphene. Alternative and adjunctive treatments hav
- Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular disease
Cochrane Systematic Reviews, 8-Dec-2010
Aspirin is the prophylactic antiplatelet drug of choice for people with cardiovascular disease. Adding a second antiplatelet drug to aspirin may produce additional benefit for those at high risk and those with established cardiovascular disease.
- Clotiapine for acute psychotic illnesses
Cochrane Systematic Reviews, 25-Jul-2012
Acute psychotic illnesses, especially when associated with agitated or violent behaviour, require urgent pharmacological tranquillisation or sedation. Clotiapine, a dibenzothiazepine neuroleptic, is being used for this purpose in several countries.
- Clozapine versus typical neuroleptic medication for schizophrenia
Cochrane Systematic Reviews, 10-Nov-2009
Long-term drug treatment of schizophrenia with typical antipsychotic drugs has limitations: 25 to 33% of sufferers have illnesses that are treatment resistant. Clozapine is an antipsychotic drug, which is claimed to have superior efficacy and to cause few
- Colchicine as an oral corticosteroid sparing agent for asthma
Cochrane Systematic Reviews, 5-Nov-2009
Oral corticosteroids are used as a treatment for asthma, but they are often associated with serious side effects. Colchicine is an anti-inflammatory, immuno modulating agent, which could potentially have a beneficial effect in the treatment of asthma as w
- Combination pharmacotherapy for the treatment of neuropathic pain in adults
Cochrane Systematic Reviews, 8-Jun-2012
Pharmacotherapy remains an important modality for the treatment of neuropathic pain. However, as monotherapy current drugs are associated with limited efficacy and dose-related side effects. Combining two or more different drugs may improve analgesic effi
- Combined corticosteroid and long-acting beta2-agonist in one inhaler versus inhaled corticosteroids alone for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 29-Aug-2013
Both long-acting beta2-agonists and inhaled corticosteroids have been recommended in guidelines for the treatment of chronic obstructive pulmonary disease (COPD). Their co-administration in a combined inhaler is intended to facilitate adherence to medicat
- Combined corticosteroid and long-acting beta2-agonist in one inhaler versus long-acting beta2-agonists for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 12-Apr-2013
Both inhaled steroids (ICS) and long-acting beta2-agonists (LABA) are used in the management of chronic obstructive pulmonary disease (COPD). This updated review compared compound LABA plus ICS therapy (LABA/ICS) with the LABA component drug given alone.
- Combined corticosteroid and long‐acting beta2‐agonist in one inhaler versus placebo for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 10-Nov-2013
Both long-acting beta2-agonists (LABA) and inhaled corticosteroids (ICS) have been recommended in guidelines for the treatment of chronic obstructive pulmonary disease (COPD). Their coadministration in a combination inhaler may facilitate adherence to med
- Combined psychotherapy plus antidepressants for panic disorder with or without agoraphobia
Cochrane Systematic Reviews, 31-Oct-2008
Panic disorder can be treated with pharmacotherapy, psychotherapy or in combination, but the relative merits of combined therapy have not been well established.
- Commercial versus home-made spacers in delivering bronchodilator therapy for acute therapy in children
Cochrane Systematic Reviews, 17-Jan-2011
Strong evidence supports the use of metered-dose inhalers combined with a spacer for delivering rapid-acting inhaled beta-2 agonists in the treatment of acute exacerbations of asthma in children. The high cost and lack of availability of commercially prod
- Computerized advice on drug dosage to improve prescribing practice
Cochrane Systematic Reviews, 7-Nov-2013
Maintaining therapeutic concentrations of drugs with a narrow therapeutic window is a complex task. Several computer systems have been designed to help doctors determine optimum drug dosage. Signi?cant improvements in health care could be achieved if comp
