- Duration of adjuvant chemotherapy for patients with non-metastatic colorectal cancer
Cochrane Systematic Reviews, 29-Oct-2009
Surgery of primary tumour is the backbone of colorectal cancer treatment (CRC). But in stage III cancer, metastatic or local relapse is often observed (50%). So, adjuvant treatment is always considered in this setting. The best treatment duration of hypot - Duration of antibacterial treatment for uncomplicated urinary tract infection in women
Cochrane Systematic Reviews, 28-Sep-2008
Uncomplicated urinary tract infection (UTI) is a common disease, occurring frequently in young sexually active women. In the past, seven day antibiotic therapy was recommended while the current practice is to treat uncomplicated UTI for three days. - Duration of intravenous antibiotic therapy in people with cystic fibrosis
Cochrane Systematic Reviews, 5-Sep-2019
Progressive lung damage from recurrent exacerbations is the major cause of mortality and morbidity in cystic fibrosis. Life expectancy of people with cystic fibrosis has increased dramatically in the last 40 years. One of the major reasons for this increa - Duration of treatment for asymptomatic bacteriuria during pregnancy
Cochrane Systematic Reviews, 11-Nov-2015
A previous Cochrane systematic review has shown that antibiotic drug treatment of asymptomatic bacteriuria in pregnant women substantially decreases the risk of pyelonephritis and reduces the risk of preterm delivery. However, it is not clear whether sing - Duration of treatment with vitamin K antagonists in symptomatic venous thromboembolism
Cochrane Systematic Reviews, 5-Aug-2014
Currently, the most frequently used secondary treatment for patients with venous thromboembolism (VTE) consists of vitamin K antagonists (VKA) targeted at an international normalized ratio (INR) of 2.5 (range 2.0 to 3.0). However, based on the continuing - Dynamic compression plating versus locked intramedullary nailing for humeral shaft fractures in adults
Cochrane Systematic Reviews, 3-May-2011
Surgical fixation of fractures of the shaft of the humerus generally involves plating or nailing. It is unclear whether one method is more effective than the other. - Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis
Cochrane Systematic Reviews, 7-Oct-2009
An up-to-date overview of the effectiveness and safety of dynamic exercise therapy (exercise therapy with a sufficient intensity, duration, and frequency to establish improvement in aerobic capacity and/or muscle strength) is lacking. - Dynamic exercise therapy for treating rheumatoid arthritis
Cochrane Systematic Reviews, 12-May-2009
Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting the musculoskeletal system. Inflammation of the joints and tendons results in pain, swelling and restricted movement, eventually leading to radiological changes and deformities. Exercis - Ear drops for the removal of ear wax
Cochrane Systematic Reviews, 24-Jul-2018
Problems attributed to the accumulation of wax (cerumen) are among the most common reasons for people to present to their general practitioners with ear trouble. Treatment for this condition often involves use of a wax softening agent (cerumenolytic) to d - Ear drops for the removal of ear wax
Cochrane Systematic Reviews, 25-Jul-2018
Ear wax (cerumen) is a normal bodily secretion that can become a problem when it obstructs the ear canal. Symptoms attributed to wax (such as deafness and pain) are among the commonest reasons for patients to present to primary care with ear trouble. - Early (< 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants
Cochrane Systematic Reviews, 21-Oct-2021
Bronchopulmonary dysplasia (BPD) remains a major problem for infants born extremely preterm. Persistent inflammation in the lungs is important in its pathogenesis. Systemic corticosteroids have been used to prevent or treat BPD because of their potent ant - Early additional food and fluids for healthy breastfed full‐term infants
Cochrane Systematic Reviews, 30-Aug-2016
Health organisations recommend exclusive breastfeeding for six months. However, the addition of other fluids or foods before six months is common in many countries. Recently, research has suggested that introducing solid food at around four months of age - Early administration of inhaled corticosteroids for preventing chronic lung disease in very low birth weight preterm neonates
Cochrane Systematic Reviews, 4-Jan-2017
Chronic lung disease (CLD) remains a common complication among preterm infants. There is increasing evidence that inflammation plays an important role in the pathogenesis of CLD. Due to their strong anti-inflammatory properties, corticosteroids are an att - Early amniocentesis versus transabdominal chorion villus sampling for prenatal diagnosis
Cochrane Systematic Reviews, 16-Oct-2008
A major disadvantage of amniocentesis is that test results are usually available only after 18 weeks gestation. Early amniocentesis can now be done between 9 to 14 weeks gestation. - Early amniotomy and early oxytocin for prevention of, or therapy for, delay in first stage spontaneous labour compared with routine care
Cochrane Systematic Reviews, 7-Aug-2013
Caesarean section rates are over 20% in many developed countries. The main diagnosis contributing to the high rate in nulliparae is dystocia or prolonged labour. The present review assesses the effects of a policy of early amniotomy with early oxytocin ad - Early and late adverse renal effects after potentially nephrotoxic treatment for childhood cancer
Cochrane Systematic Reviews, 11-Mar-2019
Improvements in diagnostics and treatment for paediatric malignancies resulted in a major increase in survival. However, childhood cancer survivors (CCS) are at risk of developing adverse effects caused by multimodal treatment for their malignancy. Nephro - Early compared with delayed oral fluids and food after caesarean section
Cochrane Systematic Reviews, 22-Jul-2002
It is customary for fluids and/or food to be withheld for a period of time after abdominal operations. After caesarean section, practices vary considerably. These discrepancies raise concern as to the bases of different practices. - Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants
Cochrane Systematic Reviews, 24-Nov-2015
Infants born preterm are at increased risk of developing cognitive and motor impairment compared with infants born at term. Early developmental interventions have been provided in the clinical setting with the aim of improving overall functional outcomes - Early discharge hospital at home
Cochrane Systematic Reviews, 26-Jun-2017
Early discharge hospital at home is a service that provides active treatment by healthcare professionals in the patient's home for a condition that otherwise would require acute hospital inpatient care. This is an update of a Cochrane review. - Early discharge with home support of gavage feeding for stable preterm infants who have not established full oral feeds
Cochrane Systematic Reviews, 8-Jul-2015
Early discharge of stable preterm infants still requiring gavage feeds offers the benefits of uniting families sooner and reducing healthcare and family costs compared with discharge home when on full sucking feeds. Potential disadvantages of early discha
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