Showing 221-240 of 753 for: Cochrane Systematic Reviews > Pharmacotherapeutics
- Concomitant chemotherapy and radiation therapy for cancer of the uterine cervix
Cochrane Systematic Reviews, 11-Feb-2015
The National Cancer Institute (USA) alert in February 1999 stated that concomitant chemoradiotherapy should be considered for all patients with cervical cancer, based on evidence from five randomised controlled trials (RCTs).
- Continuous versus intermittent beta-agonists for acute asthma
Cochrane Systematic Reviews, 10-Mar-2011
Patients with acute asthma treated in the emergency department are frequently treated with intermittent inhaled beta-agonists delivered by nebulisation. The use of continuous beta-agonist (CBA) via nebulisation in the emergency setting may offer additiona
- Corticosteroid injections for shoulder pain
Cochrane Systematic Reviews, 21-Sep-2008
While many treatments, including corticosteroid injections in and around the shoulder, are advocated to be of benefit for shoulder pain, few are of proven efficacy. This review of corticosteroid injections for shoulder pain is one in a series of reviews o
- Corticosteroids for acute bacterial meningitis
Cochrane Systematic Reviews, 15-Mar-2016
In experimental studies, the outcome of bacterial meningitis has been related to the severity of inflammation in the subarachnoid space. Corticosteroids reduce this inflammatory response.
- Corticosteroids for acute ischaemic stroke
Cochrane Systematic Reviews, 17-Jul-2011
The majority of strokes are due to cerebral infarction. Ischaemic cerebral tissue tends to develop cytotoxic oedema which, if the blood-brain barrier is disrupted, may be followed by vasogenic oedema. Large infarcts can develop life-threatening massive oe
- Corticosteroids for acute severe asthma in hospitalised patients
Cochrane Systematic Reviews, 22-Jul-2008
Corticosteroids are currently used routinely in the management of acute severe asthma. The optimal dose and route of administration continues to be debated. Some investigators have reported a greater benefit of higher doses of corticosteroids in the manag
- Corticosteroids for acute traumatic brain injury
Cochrane Systematic Reviews, 11-May-2009
Traumatic brain injury is a leading cause of death and disability. Corticosteroids have been widely used in treating people with traumatic brain injury.
- Corticosteroids for aneurysmal subarachnoid haemorrhage and primary intracerebral haemorrhage
Cochrane Systematic Reviews, 4-Aug-2008
Corticosteroids, particularly dexamethasone, are commonly used for treatments in patients with subarachnoid haemorrhage (SAH) and primary intracerebral haemorrhage (PICH) despite the lack of evidence.
- Corticosteroids for cervical ripening and induction of labour
Cochrane Systematic Reviews, 11-Aug-2009
The role of corticosteroids in the process of labour is not well understood. Animal studies have shown the importance of cortisol secretion by the fetal adrenal gland in initiating labour in sheep. Infusion of glucocorticosteroids into the fetus has also
- Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy
Cochrane Systematic Reviews, 23-Dec-2014
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a progressive or relapsing and remitting paralysing illness probably due to an autoimmune response which should benefit from corticosteroids. Non-randomised studies suggest that corticost
- Corticosteroids for dengue infection
Cochrane Systematic Reviews, 26-Jun-2014
Dengue is a common and important mosquito-borne viral infection. In many low- and middle-income countries it is endemic and is an important public health problem. Severe dengue is an important cause of death in children. There is no specific treatment for
- Corticosteroids for Guillain-Barré syndrome
Cochrane Systematic Reviews, 13-Jun-2012
Guillain-Barré syndrome (GBS) is an acute paralysing disease caused by inflammation of the peripheral nerves, which corticosteroids would be expected to benefit.
- Corticosteroids for HELLP syndrome in pregnancy
Cochrane Systematic Reviews, 10-May-2009
Hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome is a severe form of pre-eclampsia. Pre-eclampsia is a multi-system disease of pregnancy associated with an increase in blood pressure and increased perinatal and maternal morbidity and m
- Corticosteroids for hospitalised children with acute asthma
Cochrane Systematic Reviews, 22-Jul-2008
Systemic corticosteroids are used routinely in the management of children with severe acute asthma. There is a lack of consensus regarding the agent, dose and route of corticosteroid administration.
- Corticosteroids for idiopathic pulmonary fibrosis
Cochrane Systematic Reviews, 30-Nov-2009
Idiopathic pulmonary fibrosis (IPF) is a disease with significant morbidity and mortality. Patients short survival time, high mortality and generally rapid decline raise the importance of early treatment. Current guidelines suggest a combination of cortic
- Corticosteroids for maintenance of remission in Crohn's disease
Cochrane Systematic Reviews, 13-Jul-2008
The efficacy of corticosteroids in the setting of maintenance therapy for Crohn's disease has never been clearly demonstrated. It would be important to determine, based upon the currently available data from controlled trials, if the use of chronic cortic
- Corticosteroids for managing tuberculous meningitis
Cochrane Systematic Reviews, 25-Oct-2008
Tuberculous meningitis, a serious form of tuberculosis that affects the meninges covering the brain and spinal cord, is associated with high mortality and disability among survivors. Corticosteroids have been used as an adjunct to antituberculous drugs to
- Corticosteroids for myasthenia gravis
Cochrane Systematic Reviews, 10-May-2011
Although widely accepted as an appropriate immunosuppressive therapy, the efficacy of glucocorticosteroid treatment has only rarely been tested in controlled studies. This is an update of a Cochrane review first published in 2005 and previously updated in
- Corticosteroids for preventing postherpetic neuralgia
Cochrane Systematic Reviews, 27-Feb-2013
Postherpetic neuralgia is a common, serious painful complication of herpes zoster. Corticosteroids are anti-inflammatory and might be beneficial. This is an update of a review first published in 2008 and previously updated in 2010.
- Corticosteroids for preventing relapse following acute exacerbations of asthma
Cochrane Systematic Reviews, 22-Jul-2008
Acute asthma is responsible for many emergency department (ED) visits annually. Between 12 to 16% will relapse to require additional interventions within two weeks of ED discharge. Treatment of acute asthma is based on rapid reversal of bronchospasm and r