Showing 221-240 of 498 for: Cochrane Systematic Reviews > Neurologic 
- Immunotherapy for IgM anti‐myelin‐associated glycoprotein paraprotein‐associated peripheral neuropathies
Cochrane Systematic Reviews, 4-Oct-2016
Serum monoclonal anti-myelin-associated glycoprotein (anti-MAG) antibodies may be pathogenic in some people with immunoglobulin M (IgM) paraprotein and demyelinating neuropathy. Immunotherapies aimed at reducing the level of these antibodies might be expe
- Indomethacin for Alzheimer's disease
Cochrane Systematic Reviews, 5-May-2008
Inflammatory processes involving cytokines, prostaglandins, free radicals and glial cells have been implicated in the pathogenesis of Alzheimer's disease. Non-steroidal anti-inflammatory drugs such as indomethacin attenuate inflammatory reactions. Hence,
- Interferon beta for secondary progressive multiple sclerosis
Cochrane Systematic Reviews, 29-Nov-2011
Therapy with either recombinant beta-1a or beta-1b interferons (IFNs) is worldwide approved for Relapsing Remitting Multiple Sclerosis (RRMS). A major unanswered question is whether this treatment is able to safely reverse or retard the progressive phase
- Interferon in relapsing‐remitting multiple sclerosis
Cochrane Systematic Reviews, 23-Oct-2001
Recombinant interferons have been shown to suppress both the clinical and magnetic resonance imaging (MRI) measures of disease activity in patients with relapsing remitting multiple sclerosis (RRMS).
- Interventions for apathy after traumatic brain injury
Cochrane Systematic Reviews, 15-Apr-2009
Apathy is a deficiency in overt behavioural, emotional and cognitive components of goal-directed behaviour. It is a common occurrence after traumatic brain injury (TBI), with widespread impact. We have systematically reviewed studies examining the effecti
- Interventions for apraxia of speech following stroke
Cochrane Systematic Reviews, 19-Oct-2005
Apraxia of speech is a communication disorder that can affect stroke patients. Several different intervention strategies are undertaken by speech and language therapists working with this patient group.
- Interventions for drooling in children with cerebral palsy
Cochrane Systematic Reviews, 25-Sep-2012
Drooling is a common problem for children with cerebral palsy (CP). This can be distressing for these children as well as for their parents and caregivers. The consequences of drooling include risk of social rejection, damp and soiled clothing, unpleasant
- Interventions for dysarthria due to stroke and other adult‐acquired, non‐progressive brain injury
Cochrane Systematic Reviews, 25-Jan-2017
Dysarthria is an acquired speech disorder following neurological injury that reduces intelligibility of speech due to weak, imprecise, slow and/or unco-ordinated muscle control. The impact of dysarthria goes beyond communication and affects psychosocial f
- Interventions for dysphagia in long‐term, progressive muscle disease
Cochrane Systematic Reviews, 9-Feb-2016
Normal swallowing function is divided into oral, pharyngeal, and oesophageal phases. The anatomy and physiology of the oral cavity facilitates an oral preparatory phase of swallowing, in which food and liquid are pushed towards the pharynx by the tongue.
- Interventions for idiopathic intracranial hypertension
Cochrane Systematic Reviews, 7-Aug-2015
Idiopathic intracranial hypertension (IIH) has an estimated incidence of one to three people per 100,000 people per year, and occurs most commonly in obese, young women. IIH is associated with severe morbidity, notably due to a significant threat to sight
- Interventions for motor apraxia following stroke
Cochrane Systematic Reviews, 25-Aug-2008
Apraxia is a cognitive disorder that can occur after stroke. It prevents a person from carrying out a learned movement. Various interventions are used to treat apraxia but evidence of their benefit has been lacking.
- Interventions for preventing delirium in hospitalised non‐ICU patients
Cochrane Systematic Reviews, 11-Mar-2016
Delirium is a common mental disorder, which is distressing and has serious adverse outcomes in hospitalised patients. Prevention of delirium is desirable from the perspective of patients and carers, and healthcare providers. It is currently unclear, howev
- Interventions for preventing falls in elderly people
Cochrane Systematic Reviews, 10-Nov-2009
Approximately 30 per cent of people over 65 years of age and living in the community fall each year; the number is higher in institutions. Although less than one fall in 10 results in a fracture, a fifth of fall incidents require medical attention.
- Interventions for preventing neuropathy caused by cisplatin and related compounds
Cochrane Systematic Reviews, 27-Feb-2014
Cisplatin and several related antineoplastic drugs used to treat many types of solid tumours are neurotoxic, and most patients completing a full course of cisplatin chemotherapy develop a clinically detectable sensory neuropathy. Effective neuroprotective
- Interventions for the treatment of Morton's neuroma
Cochrane Systematic Reviews, 19-Jul-2004
Morton's neuroma is a common, paroxysmal neuralgia affecting the web spaces of the toes, typically the third. The pain is often so debilitating that patients become anxious about walking or even putting their foot to the ground. Insoles, corticosteroid in
- Interventions for treating burning mouth syndrome
Cochrane Systematic Reviews, 18-Nov-2016
Burning mouth syndrome (BMS) is a term used for oral mucosal pain (burning pain or discomfort in the tongue, lips or entire oral cavity) without identifiable cause. General population prevalence varies from 0.1% to 3.9%. Many BMS patients indicate anxiety
- Intraoperative mild hypothermia for postoperative neurological deficits in people with intracranial aneurysm
Cochrane Systematic Reviews, 22-Mar-2016
Rupture of an intracranial aneurysm causes aneurysmal subarachnoid haemorrhage, which is one of the most devastating clinical conditions. It can be classified into five Grades using the Hunt-Hess or World Federation of Neurological Surgeons (WFNS) scale.
- Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy
Cochrane Systematic Reviews, 20-Dec-2013
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) causes progressive or relapsing weakness and numbness of the limbs, developing over at least two months. Uncontrolled studies suggest that intravenous immunoglobulin (IVIg) helps. This revie
- Intravenous immunoglobulin for Guillain‐Barré syndrome
Cochrane Systematic Reviews, 19-Sep-2014
Guillain-Barré syndrome (GBS) is an acute, paralysing, inflammatory peripheral nerve disease. Intravenous immunoglobulin (IVIg) is beneficial in other autoimmune diseases. This is an update of a review first published in 2001 and previously updated in 200
- Intravenous immunoglobulin for myasthenia gravis
Cochrane Systematic Reviews, 12-Dec-2012
Myasthenia gravis is an autoimmune disease in which autoantibodies interfere with neuromuscular transmission. As with other autoimmune diseases, people with myasthenia gravis would be expected to benefit from intravenous immunoglobulin (IVIg). This is an
