- Erythropoiesis‐stimulating agents for anaemia in adults with chronic kidney disease: a network meta‐analysis
Cochrane Systematic Reviews, 13-Feb-2023
Erythropoiesis-stimulating agents (ESAs) are commonly used to treat anaemia in people with chronic kidney disease (CKD). However, their use has been associated with cardiovascular events. This is an update of a Cochrane review first published in 2014. - Erythropoiesis‐stimulating agents for anaemia in chronic heart failure patients
Cochrane Systematic Reviews, 20-Jan-2010
Chronic heart failure (CHF) is a leading cause of morbidity and mortality worldwide. Anaemia is a common (12-55%) co-morbid condition and is associated with worsening symptoms and increased mortality. Anaemia is treatable and can be targeted in the treatm - Erythropoiesis‐stimulating agents for anemia in rheumatoid arthritis
Cochrane Systematic Reviews, 28-Feb-2013
Rheumatoid arthritis (RA) is a chronic and systemic inflammatory disorder that mainly affects the small joints of the hands and feet. Erythropoiesis-stimulating agents have been used to treat anemia, one of the extra-articular manifestations of RA. Althou - Erythropoietin as an adjuvant treatment with (chemo) radiation therapy for head and neck cancer
Cochrane Systematic Reviews, 8-Jul-2009
Tumour hypoxia increases tumour invasiveness and has a negative impact on response to therapy. Hypoxic tumours are also associated with severely anaemic individuals. It has therefore been hypothesised that correcting anaemia, by increasing haemoglobin lev - Erythropoietin or darbepoetin for patients with cancer
Cochrane Systematic Reviews, 5-Nov-2012
Anaemia associated with cancer and cancer therapy is an important clinical factor in the treatment of malignant diseases. Therapeutic alternatives are recombinant human erythropoiesis stimulating agents (ESAs) and red blood cell transfusions. - Erythropoietin or Darbepoetin for patients with cancer ‐ meta‐analysis based on individual patient data
Cochrane Systematic Reviews, 8-Jul-2009
Erythropoiesis-stimulating agents (ESAs) reduce anemia in cancer patients and may improve quality of life, but there are concerns that ESAs might increase mortality. - Erythropoietin plus iron versus control treatment including placebo or iron for preoperative anaemic adults undergoing non‐cardiac surgery
Cochrane Systematic Reviews, 13-Aug-2020
Approximately 30% of adults undergoing non-cardiac surgery suffer from preoperative anaemia. Preoperative anaemia is a risk factor for mortality and adverse outcomes in different surgical specialties and is frequently the reason for blood transfusion. The - Escitalopram versus other antidepressive agents for depression
Cochrane Systematic Reviews, 15-Apr-2009
Although pharmacological and psychological interventions are both effective for major depression, antidepressant drugs remain the mainstay of treatment in primary and secondary care settings. During the last 20 years, antidepressant prescribing has risen - Eslicarbazepine acetate add‐on therapy for drug‐resistant focal epilepsy
Cochrane Systematic Reviews, 22-Jun-2021
This is an update of a review first published in 2011, and last updated in 2017. - Estrogen for schizophrenia
Cochrane Systematic Reviews, 10-Nov-2009
In terms of clinical outcomes, women with schizophrenia seem to fare better then men, but appear more vulnerable to psychotic illness in the period after birth and menopause. As these vulnerable periods to psychosis are associated with estrogen withdrawal - Eszopiclone for insomnia
Cochrane Systematic Reviews, 10-Sep-2018
Insomnia is a major public health issue affecting between 6% to 10% of the adult population in Western countries. Eszopiclone is a hypnotic drug belonging to a newer group of hypnotic agents, known as new generation hypnotics, which was marketed as being - Etanercept for the treatment of rheumatoid arthritis
Cochrane Systematic Reviews, 2-Apr-2013
Etanercept is a soluble tumour necrosis factor alpha-receptor disease-modifying anti-rheumatic drug (DMARD) for the treatment of rheumatoid arthritis (RA). - Ethamsylate for the prevention of morbidity and mortality in preterm or very low birth weight infants
Cochrane Systematic Reviews, 20-Jan-2010
Ethamsylate decreases blood loss in certain clinical situations such as menorrhagia and following some surgical procedures. This potential to reduce bleeding has led to the hypothesis that it may have a role to play in reducing intraventricular haemorrhag - Ethanol for preventing preterm birth in threatened preterm labor
Cochrane Systematic Reviews, 5-Nov-2015
Preterm birth is the leading cause of death and disability in newborns worldwide. A wide variety of tocolytic agents have been utilized to delay birth for women in preterm labor. One of the earliest tocolytics utilized for this purpose was ethanol infusio - Ethical case interventions for adult patients
Cochrane Systematic Reviews, 22-Jul-2019
Decisions in clinical medicine can be associated with ethical challenges. Ethical case interventions (e.g. ethics committee, moral case deliberation) identify and analyse ethical conflicts which occur within the context of care for patients. Ethical case - Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents
Cochrane Systematic Reviews, 21-Jan-2021
This is an updated version of the Cochrane Review previously published in 2019. - Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
Cochrane Systematic Reviews, 23-Jan-2008
Osteoporosis is an abnormal reduction in bone mass and bone deterioration leading to increased fracture risk. Etidronate belongs to the bisphosphonate class of drugs which act to inhibit bone resorption by interfering with the activity of osteoclasts. - Etrolizumab for induction of remission in ulcerative colitis
Cochrane Systematic Reviews, 2-Dec-2015
Etrolizumab (rhuMAb beta7) is an anti-integrin that selectively targets the ß7 subunits of the a4ß7 and aEß7 integrins, which are involved in the pathogenesis of ulcerative colitis. - Evaluation of follow‐up strategies for patients with epithelial ovarian cancer following completion of primary treatment
Cochrane Systematic Reviews, 8-Sep-2014
Ovarian cancer is the sixth most common cancer and seventh commonest cause of death in women worldwide. Traditionally, many people who have been treated for cancer undergo long-term follow-up in secondary care. However, it has been suggested that the use - Evaluation of the efficacy and safety of adjuvant treatment to levodopa therapy in Parkinson´s disease patients with motor complications
Cochrane Systematic Reviews, 17-Jun-2010
One of the complications of long-term treatment of Parkinson's disease (PD) with levodopa is the development of motor complications. Generally, when motor complications develop, clinicians add in an additional drug (to the levodopa regimen) from one of th
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