Showing 281-300 of 746 for: Cochrane Systematic Reviews > Pharmacotherapeutics 
- Early administration of inhaled corticosteroids for preventing chronic lung disease in very low birth weight preterm neonates
Cochrane Systematic Reviews, 4-Jan-2017
Chronic lung disease (CLD) remains a common complication among preterm infants. There is increasing evidence that inflammation plays an important role in the pathogenesis of CLD. Due to their strong anti-inflammatory properties, corticosteroids are an att
- Early emergency department treatment of acute asthma with systemic corticosteroids
Cochrane Systematic Reviews, 22-Jan-2001
The airway edema and secretions associated with acute asthma are most effectively treated with anti-inflammatories such as corticosteroids delivered by inhaled, oral, intravenous or intra-muscular routes. There is an unresolved debate about the use of sys
- Early use of inhaled corticosteroids in the emergency department treatment of acute asthma
Cochrane Systematic Reviews, 12-Dec-2012
Systemic corticosteroid therapy is central to the management of acute asthma. The use of inhaled corticosteroids (ICS) may also be beneficial in this setting.
- Effects of glucocorticoids on radiological progression in rheumatoid arthritis
Cochrane Systematic Reviews, 16-Sep-2008
Glucocorticoid use in rheumatoid arthritis (RA) is widespread. Two Cochrane Reviews have been published examining the short term clinical benefit of low dose glucocorticoids compared to non-steroidal anti-inflammatory drugs and demonstrate good short term
- Effects of nonsteroidal anti‐inflammatory drugs on postoperative renal function in adults with normal renal function
Cochrane Systematic Reviews, 18-Apr-2007
Nonsteroidal anti-inflammatory drugs (NSAIDs) can play a major role in the management of acute pain in the peri-operative period. However, there are conflicting views on whether NSAIDs are associated with adverse renal effects.
- Eicosapentaenoic acid (EPA, an omega‐3 fatty acid from fish oils) for the treatment of cancer cachexia
Cochrane Systematic Reviews, 24-Jan-2007
Cancer cachexia is a distressing weight loss syndrome commonly seen in advanced cancer patients. It is associated with reduced quality of life and shorter survival time. Eicosapentaenoic acid (EPA) is a long chain polyunsaturated fatty acid found naturall
- Electroconvulsive therapy for schizophrenia
Cochrane Systematic Reviews, 4-Aug-2009
Electroconvulsive therapy (ECT) involves the induction of a seizure for therapeutic purposes by the administration of a variable frequency electrical stimulus shock via electrodes applied to the scalp. The effects of its use in people with schizophrenia a
- Eletriptan for acute migraine
Cochrane Systematic Reviews, 10-Jun-2019
Eletriptan (Relpax) is a new triptan soon to be made available by prescription for the treatment of acute migraine. Currently five triptans are available by prescription and more are under development. In light of the many drugs for treating acute migrain
- Empiric antibiotic coverage of atypical pathogens for community‐acquired pneumonia in hospitalized adults
Cochrane Systematic Reviews, 12-Sep-2012
Community-acquired pneumonia (CAP) is caused by various pathogens, traditionally divided into 'typical' and 'atypical'. Initial antibiotic treatment of CAP is usually empirical, customarily covering both typical and atypical pathogens. To date, no suffici
- Endoscopic pneumatic dilation versus botulinum toxin injection in the management of primary achalasia
Cochrane Systematic Reviews, 8-Dec-2014
Achalasia is an oesophageal motility disorder, of unknown cause, which results in increased lower oesophageal sphincter (LOS) tone and symptoms of difficulty swallowing. Treatments are aimed at reducing the LOS tone. Current endoscopic therapeutic options
- Enteral nutritional therapy for induction of remission in Crohn's disease
Cochrane Systematic Reviews, 1-Apr-2018
Corticosteroids are often preferred over enteral nutrition (EN) as induction therapy for Crohn's disease (CD). Prior meta-analyses suggest that corticosteroids are superior to EN for induction of remission in CD. Treatment failures in EN trials are often
- Epidural pain relief versus systemic opioid‐based pain relief for abdominal aortic surgery
Cochrane Systematic Reviews, 5-Jan-2016
Epidural analgesia offers greater pain relief compared to systemic opioid-based medications, but its effect on morbidity and mortality is unclear. This review was originally published in 2006 and was updated in 2012 and again in 2016.
- Epidural versus non‐epidural or no analgesia for pain management in labour
Cochrane Systematic Reviews, 21-May-2018
Epidural analgesia is a central nerve block technique achieved by injection of a local anaesthetic close to the nerves that transmit pain, and is widely used as a form of pain relief in labour. However, there are concerns about unintended adverse effects
- Erythromycin for the prevention and treatment of feeding intolerance in preterm infants
Cochrane Systematic Reviews, 8-May-2008
Functional immaturity of gastrointestinal motility predisposes preterm infants to feeding intolerance. Erythromycin is a motilin agonist that exerts its prokinetic effect by stimulating propagative contractile activity in the interdigestive phase.
- Erythromycin for the prevention of chronic lung disease in intubated preterm infants at risk for, or colonized or infected with Ureaplasma urealyticum
Cochrane Systematic Reviews, 22-Oct-2008
Controversy exists over whether or not Ureaplasma urealyticum colonization or infection of the respiratory tract contributes to the severity of chronic lung disease (CLD), a major cause of morbidity and mortality in preterm infants.
- Erythropoietin as an adjuvant treatment with (chemo) radiation therapy for head and neck cancer
Cochrane Systematic Reviews, 8-Jul-2009
Tumour hypoxia increases tumour invasiveness and has a negative impact on response to therapy. Hypoxic tumours are also associated with severely anaemic individuals. It has therefore been hypothesised that correcting anaemia, by increasing haemoglobin lev
- Erythropoietin or Darbepoetin for patients with cancer ‐ meta‐analysis based on individual patient data
Cochrane Systematic Reviews, 8-Jul-2009
Erythropoiesis-stimulating agents (ESAs) reduce anemia in cancer patients and may improve quality of life, but there are concerns that ESAs might increase mortality.
- Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
Cochrane Systematic Reviews, 23-Jan-2008
Osteoporosis is an abnormal reduction in bone mass and bone deterioration leading to increased fracture risk. Etidronate belongs to the bisphosphonate class of drugs which act to inhibit bone resorption by interfering with the activity of osteoclasts.
- Fibrinolytic therapy for intraventricular hemorrhage in adults
Cochrane Systematic Reviews, 22-Jul-2002
Spontaneous or secondary intraventricular hemorrhage is a marker of poor prognosis for hemorrhagic stroke. It can cause hydrocephalus and require ventricular shunt placement, result in permanent neurological deficits or death. Fibrinolytic agents injected
- Fish oil for induction of remission in ulcerative colitis
Cochrane Systematic Reviews, 26-May-2008
Fish oil supplements, which are rich in n-3 fatty acids, may reduce inflammation, decrease the need for anti-inflammatory drugs, and promote normal weight gain in people with ulcerative colitis.
