Showing 281-300 of 503 for: Cochrane Systematic Reviews > Neurologic 
- Melatonin for the prevention and treatment of jet lag
Cochrane Systematic Reviews, 3-Mar-2009
Jet lag commonly affects air travellers who cross several time zones. It results from the body's internal rhythms being out of step with the day-night cycle at the destination. Melatonin is a pineal hormone that plays a central part in regulating bodily r
- Melatonin for the treatment of dementia
Cochrane Systematic Reviews, 16-Feb-2011
There are a number of studies that suggest a relationship between decline of melatonin function and the symptoms of dementia.
- Memantine for dementia
Cochrane Systematic Reviews, 3-Nov-2008
Memantine, a low affinity antagonist to glutamate NMDA receptors, may prevent excitatory neurotoxicity in dementia.
- Memory rehabilitation for people with multiple sclerosis
Cochrane Systematic Reviews, 18-Oct-2021
Problems with cognition, particularly memory, are common in people with multiple sclerosis (MS) and can affect their ability to complete daily activities and can negatively affect quality of life. Over the last few years, there has been considerable growt
- Metal protein attenuating compounds for the treatment of Alzheimer's dementia
Cochrane Systematic Reviews, 20-Feb-2014
Alzheimer's dementia (AD) may be caused by the formation of extracellular senile plaques comprised of beta-amyloid (Aß). In vitro and mouse model studies have demonstrated that metal protein attenuating compounds (MPACs) promote the solubilisation and cle
- Methadone for cancer pain
Cochrane Systematic Reviews, 17-Jun-2013
Methadone is an opioid used in the management of cancer pain. A particular role in neuropathic pain has been suggested. The quest for evidence based palliative care prompted a formal appraisal of methadone in comparison with other analgesics. This is an u
- Methotrexate for multiple sclerosis
Cochrane Systematic Reviews, 5-Sep-2010
Methotrexate is a potent immunosuppressant which in theory could reduce relapse rates and delay disease progression in multiple sclerosis (MS). Subsequently, clinical trials of methotrexate have been conducted in people with MS.
- Metrifonate for Alzheimer's disease
Cochrane Systematic Reviews, 18-Mar-2008
Metrifonate is a long-acting irreversible cholinesterase inhibitor, originally used to treat schistosomiasis. Its potential to enhance central nervous system cholinergic neurotransmission led to clinical trials for the treatment of people with Alzheimer's
- Milnacipran for pain in fibromyalgia in adults
Cochrane Systematic Reviews, 20-Oct-2015
This is an updated version of the original Cochrane review published in Issue 3, 2012. That review considered both fibromyalgia and neuropathic pain, but the efficacy of milnacipran for neuropathic pain is now dealt with in a separate review.
- Miscellaneous treatments for neuroleptic-induced tardive dyskinesia
Cochrane Systematic Reviews, 4-Oct-2011
Tardive dyskinesia is a disabling movement disorder associated with the prolonged use of neuroleptic medication. This review, one in a series examining the treatment of tardive dyskinesia, will cover miscellaneous treatments not covered elsewhere.
- Mitoxantrone for multiple sclerosis
Cochrane Systematic Reviews, 23-Oct-2013
Mitoxantrone (MX) has been shown to be moderately effective in reducing the clinical outcome measures of disease activity in multiple sclerosis (MS) patients.
- Monoamine oxidase B inhibitors for early Parkinson's disease
Cochrane Systematic Reviews, 14-Nov-2011
Monoamine oxidase B (MAO-B) inhibitors slow disease progression in Parkinson's disease (PD) but clinical trials have produced conflicting results.
- Monoamine oxidase B inhibitors versus other dopaminergic agents in early Parkinson's disease
Cochrane Systematic Reviews, 28-May-2009
It has been postulated that monoamine oxidase B (MAO-B) inhibitors alter disease progression in Parkinson's disease (PD) but trials have produced conflicting results.
- Monoamine oxidase inhibitors (MAOIs) for fibromyalgia syndrome
Cochrane Systematic Reviews, 8-Mar-2012
Fibromyalgia (FM) syndrome is a chronic condition of unknown aetiology characterised by musculoskeletal pain that often co-exists with sleep disturbance, cognitive dysfunction and fatigue. Patients often report high disability levels and poor quality of l
- Monoaminergic agonists for acute traumatic brain injury
Cochrane Systematic Reviews, 6-Dec-2010
Although there have been considerable gains in understanding the cascade of events that lead to secondary injury after traumatic brain injury (TBI), efforts to translate this understanding into new therapeutic, so-called neuroprotective approaches, have s
- Multidisciplinary care for adults with amyotrophic lateral sclerosis or motor neuron disease
Cochrane Systematic Reviews, 9-Nov-2011
Multidisciplinary care (MDC) is increasingly thought to be an important means of symptomatic and supportive management for motor neuron disease (MND) but the evidence base for its effectiveness is unclear. This is the first update of a review first publis
- Multidisciplinary care for Guillain-Barré syndrome
Cochrane Systematic Reviews, 7-Sep-2010
Guillain-Barré syndrome is a significant cause of new long-term disability, which is thought to be amenable to multidisciplinary care, but the evidence base for its effectiveness is unclear.
- Multi-disciplinary rehabilitation for acquired brain injury in adults of working age
Cochrane Systematic Reviews, 22-Dec-2015
Evidence from systematic reviews demonstrates that multi-disciplinary rehabilitation is effective in the stroke population, in which older adults predominate. However, the evidence base for the effectiveness of rehabilitation following acquired brain inju
- Multidisciplinary rehabilitation for adults with multiple sclerosis
Cochrane Systematic Reviews, 8-Nov-2011
Multidisciplinary (MD) rehabilitation is an important component of symptomatic and supportive treatment for Multiple Sclerosis (MS), but evidence base for its effectiveness is yet to be established.
- Muscle relaxants for non-specific low-back pain
Cochrane Systematic Reviews, 12-Aug-2008
The use of muscle relaxants in the management of non-specific low back pain is controversial. It is not clear if they are effective, and concerns have been raised about the potential adverse effects involved.
