Showing 281-300 of 644 for: Cochrane Systematic Reviews > Respiratory 
- Inhaled corticosteroids compared to placebo for prevention of exercise induced bronchoconstriction
Cochrane Systematic Reviews, 18-Jul-2007
The pathogenesis of exercise induced bronchoconstriction is likely multifactorial and is not completely understood. Inflammation plays an important role in the pathogenesis of exercise induced bronchoconstriction in asthmatic subjects but the evidence see
- Inhaled corticosteroids for bronchiectasis
Cochrane Systematic Reviews, 16-May-2018
Bronchiectasis is being increasingly diagnosed and recognised as an important contributor to chronic lung disease in both adults and children in high- and low-income countries. It is characterised by irreversible dilatation of airways and is generally ass
- Inhaled corticosteroids for cystic fibrosis
Cochrane Systematic Reviews, 4-Jul-2019
The reduction of lung inflammation is one of the goals of cystic fibrosis therapy. Inhaled corticosteroids are often used in this respect to treat children and adults with cystic fibrosis. The rationale for this is their potential to reduce lung damage ar
- Inhaled corticosteroids for non-specific chronic cough in children
Cochrane Systematic Reviews, 29-Mar-2009
Cough in isolation of other clinical features is known as non-specific cough, which has been defined as non-productive cough in the absence of identifiable respiratory disease or any known aetiology. In children with non-specific cough the possibility of
- Inhaled corticosteroids for stable chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 25-Aug-2016
The role of inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease (COPD) has been the subject of much controversy. Major international guidelines recommend selective use of ICS. Recently published meta-analyses have reported conflicting f
- Inhaled corticosteroids versus long‐acting beta2‐agonists for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 7-Dec-2011
Long-acting beta2-agonists and inhaled corticosteroids can be used as maintenance therapy by patients with moderate to severe chronic obstructive pulmonary disease. These interventions are often taken together in a combination inhaler. However, the relati
- Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma
Cochrane Systematic Reviews, 19-Apr-2006
Inhaled corticosteroids (ICS) and sodium cromoglycate (SCG) have become established as effective controller medications for children and adults with asthma, but their relative efficacy is not clear.
- Inhaled cromones for prolonged non-specific cough in children
Cochrane Systematic Reviews, 20-Jul-2010
Non-specific cough is defined as non-productive cough in the absence of identifiable respiratory disease or known aetiology. It is commonly seen in paediatric practice. These children are treated with a variety of therapies including inhaled cromones.
- Inhaled hyperosmolar agents for bronchiectasis
Cochrane Systematic Reviews, 9-May-2014
Mucus retention in the lungs is a prominent feature of bronchiectasis. The stagnant mucus becomes chronically colonised with bacteria, which elicit a host neutrophilic response. This fails to eliminate the bacteria, and the large concentration of host-der
- Inhaled magnesium sulfate in the treatment of acute asthma
Cochrane Systematic Reviews, 28-Nov-2017
Asthma exacerbations can be frequent and range in severity from mild to life-threatening. The use of magnesium sulfate (MgSO4) is one of numerous treatment options available during acute exacerbations. While the efficacy of intravenous MgSO4 has been demo
- Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults
Cochrane Systematic Reviews, 27-Jun-2016
Acute hypoxaemic respiratory failure (AHRF) and mostly acute respiratory distress syndrome (ARDS) are critical conditions. AHRF results from several systemic conditions and is associated with high mortality and morbidity in individuals of all ages. Inhale
- Inhaled nitric oxide for respiratory failure in preterm infants
Cochrane Systematic Reviews, 3-Jan-2017
Inhaled nitric oxide (iNO) is effective in term infants with hypoxic respiratory failure. The pathophysiology of respiratory failure and the potential risks of iNO differ substantially in preterm infants, necessitating specific study in this population.
- Inhaled nitric oxide for the postoperative management of pulmonary hypertension in infants and children with congenital heart disease
Cochrane Systematic Reviews, 3-Jul-2014
Nitric oxide (NO) is a prevalent molecule in humans that is responsible for many physiologic activities including pulmonary vasodilation. An exogenous, inhaled form (iNO) exists that mimics this action without affecting systemic blood pressure. This thera
- Inhaled non‐steroid anti‐inflammatories for children and adults with bronchiectasis
Cochrane Systematic Reviews, 27-Jan-2016
Chronic neutrophilic inflammation, in both the presence and absence of infection, is a feature of bronchiectasis in adults and children. The anti-inflammatory properties of non-steroid anti-inflammatory drugs (NSAIDs) may be beneficial in reducing airway
- Inhaled short acting beta2‐agonist use in chronic asthma: regular versus as needed treatment
Cochrane Systematic Reviews, 20-Jan-2003
Inhaled short-acting beta-2 agonists are the major class of bronchodilators used for relief of symptoms in asthma. There has been concern that excessive uncontrolled use of beta-2 agonists might have contributed to rises in asthma mortality seen in some c
- Inhaled short‐acting beta2‐agonists versus ipratropium for acute exacerbations of chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 22-Jan-2001
Inhaled short acting beta2 adrenergic agonists and ipratropium bromide are both used in the treatment of acute exacerbations of chronic obstructive pulmonary disease.
- Inhaled sodium cromoglycate for asthma in children
Cochrane Systematic Reviews, 8-Oct-2008
Sodium cromoglycate has been recommended as maintenance treatment for childhood asthma for many years. Its use has decreased since 1990, when inhaled corticosteroids became popular, but it is still used in many countries.
- Inhaled steroids for acute asthma following emergency department discharge
Cochrane Systematic Reviews, 12-Dec-2012
Patients with acute asthma treated in the emergency department (ED) are frequently treated with inhaled beta2-agonists and systemic corticosteroids after discharge. The use of inhaled corticosteroids (ICS) following discharge may also be beneficial in imp
- Inhaled steroids for episodic viral wheeze of childhood
Cochrane Systematic Reviews, 24-Jan-2000
Recurrent episodic wheeze in association with viral upper respiratory tract infection (URTI) is a specific clinical illness distinct from persistent atopic asthma.
- Inhaled steroids with and without regular formoterol for asthma: serious adverse events
Cochrane Systematic Reviews, 25-Sep-2019
Epidemiological evidence has suggested a link between beta2-agonists and increases in asthma mortality. There has been much debate about whether regular (daily) long-acting beta2-agonists (LABA) are safe when used in combination with inhaled corticosteroi
