Showing 301-320 of 753 for: Cochrane Systematic Reviews > Pharmacotherapeutics 
- Erythropoietin as an adjuvant treatment with (chemo) radiation therapy for head and neck cancer
Cochrane Systematic Reviews, 12-May-2009
Tumour hypoxia increases tumour invasiveness and has a negative impact on response to therapy. Hypoxic tumours are also associated with severely anaemic individuals. It has therefore been hypothesised that correcting anaemia, by increasing haemoglobin lev
- Erythropoietin or Darbepoetin for patients with cancer - meta-analysis based on individual patient data
Cochrane Systematic Reviews, 29-Sep-2010
Erythropoiesis-stimulating agents (ESAs) reduce anemia in cancer patients and may improve quality of life, but there are concerns that ESAs might increase mortality.
- Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
Cochrane Systematic Reviews, 24-May-2010
Osteoporosis is an abnormal reduction in bone mass and bone deterioration leading to increased fracture risk. Etidronate belongs to the bisphosphonate class of drugs which act to inhibit bone resorption by interfering with the activity of osteoclasts.
- Fibrinolytic therapy for intraventricular hemorrhage in adults
Cochrane Systematic Reviews, 24-Aug-2008
Spontaneous or secondary intraventricular hemorrhage is a marker of poor prognosis for hemorrhagic stroke. It can cause hydrocephalus and require ventricular shunt placement, result in permanent neurological deficits or death. Fibrinolytic agents injected
- Fish oil for induction of remission in ulcerative colitis
Cochrane Systematic Reviews, 26-May-2008
Fish oil supplements, which are rich in n-3 fatty acids, may reduce inflammation, decrease the need for anti-inflammatory drugs, and promote normal weight gain in people with ulcerative colitis.
- Fish oil for kidney transplant recipients
Cochrane Systematic Reviews, 12-May-2008
Calcineurin inhibitors used in kidney transplantation for immunosuppression have adverse effects that may contribute to nephrotoxicity and increased cardiovascular risk profile. Fish oils are rich in very long chain omega-3 fatty acids, which may reduce n
- Fluids and diuretics for acute ureteric colic
Cochrane Systematic Reviews, 10-Jan-2012
Acute ureteric colic is commonly associated with severe and debilitating pain. Theoretically, increasing fluid flow through the affected kidney might expedite stone passage, thereby improving symptoms more quickly. The efficacy and safety of interventions
- Fluoroquinolones for treating tuberculosis (presumed drug-sensitive)
Cochrane Systematic Reviews, 30-May-2013
Currently the World Health Organization only recommend fluoroquinolones for people with presumed drug-sensitive tuberculosis (TB) who cannot take standard first-line drugs. However, use of fluoroquinolones could shorten the length of treatment and improve
- Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever)
Cochrane Systematic Reviews, 16-Nov-2011
Typhoid and paratyphoid are febrile illnesses, due to a bacterial infection, which remain common in many low- and middle-income countries. The World Health Organization (WHO) currently recommends the fluoroquinolone antibiotics in areas with known resista
- Fluoxetine versus other types of pharmacotherapy for depression
Cochrane Systematic Reviews, 16-Jul-2013
Depression is common in primary care and is associated with marked personal, social and economic morbidity, thus creating significant demands on service providers. The antidepressant fluoxetine has been studied in many randomised controlled trials (RCTs)
- Flupenthixol decanoate (depot) for schizophrenia or other similar psychotic disorders
Cochrane Systematic Reviews, 23-May-2014
Long-acting depot injections of drugs such as flupenthixol decanoate are extensively used as a means of long-term maintenance treatment for schizophrenia.
- Fluphenazine decanoate (depot) and enanthate for schizophrenia
Cochrane Systematic Reviews, 25-Feb-2016
Intramuscular injections (depot preparations) offer an advantage over oral medication for treating schizophrenia by reducing poor compliance. The benefits gained by long-acting preparations, however, may be offset by a higher incidence of adverse effects.
- Fluticasone versus 'extrafine' HFA-beclomethasone dipropionate for chronic asthma in adults and children
Cochrane Systematic Reviews, 12-Jan-2010
The relative efficacy of fluticasone (FP) and beclomethasone (BDP) propelled with CFCs has been well established. The potency of HFA-BDP is thought to have been improved with new propellant and some studies suggest that extra-fine HFA-BDP may be equipoten
- Fully intermittent dosing with drugs for treating tuberculosis in adults
Cochrane Systematic Reviews, 25-Oct-2008
The number of people infected with tuberculosis continues to rise worldwide. Rifampicin-containing treatment regimens can achieve high cure rates. Intermittent drug treatment delivered in the community has the potential to improve adherence to treatment.
- Fundal pressure versus controlled cord traction as part of the active management of the third stage of labour
Cochrane Systematic Reviews, 16-Sep-2010
There are two basic interventions to help to deliver the placenta as part of the active management of the third stage of labour: (1) fundal pressure, and (2) controlled traction on the umbilical cord. Both of these methods may, in addition, have adverse o
- Fundoplication versus postoperative medication for gastro-oesophageal reflux in children with neurological impairment undergoing gastrostomy
Cochrane Systematic Reviews, 28-Aug-2013
Children with neurological impairments frequently experience feeding difficulties, which can lead to malnutrition and growth failure. Gastrostomy feeding is now the preferred method of providing nutritional support to children with neurological impairment
- Furosemide for prevention of morbidity in indomethacin-treated infants with patent ductus arteriosus
Cochrane Systematic Reviews, 12-Aug-2008
Inhibition of prostaglandin synthesis mediates closure of the ductus arteriosus and renal side effects after indomethacin administration. Because furosemide increases prostaglandin production, it could potentially help prevent indomethacin-related toxicit
- Gamma-aminobutyric acid agonists for neuroleptic-induced tardive dyskinesia
Cochrane Systematic Reviews, 18-Jan-2012
Chronic antipsychotic drug treatment may cause tardive dyskinesia (TD), a long-term movement disorder. Gamma-aminobutyric acid (GABA) agonist drugs, which have intense sedative properties and may exacerbate psychotic symptoms, have been used to treat TD.
- Gastro-oesophageal reflux treatment for asthma in adults and children
Cochrane Systematic Reviews, 29-Sep-2008
Asthma and gastro-oesophageal reflux are both common medical conditions and often co-exist. Studies have shown conflicting results concerning the effects of lower oesophageal acidification as a trigger of asthma. Furthermore, asthma might precipitate gast
- Glucocorticosteroids for primary biliary cirrhosis
Cochrane Systematic Reviews, 22-Sep-2008
Primary biliary cirrhosis is a chronic progressive cholestatic liver disease of presumed autoimmune etiology, characterised by the destruction of small intrahepatic bile ducts and the eventual development of cirrhosis and liver failure. Its progression ma
