- High initial concentration versus low initial concentration sevoflurane for inhalational induction of anaesthesia
Cochrane Systematic Reviews, 29-Jun-2016
Sevoflurane induction for general anaesthesia has been reported to be safe, reliable and well accepted by patients. Sevoflurane induction uses either low or high initial concentrations. The low initial concentration technique involves initially administer - High protein supplementation in pregnancy
Cochrane Systematic Reviews, 23-Oct-2008
Background pending. - High versus low blood pressure targets for cardiac surgery while on cardiopulmonary bypass
Cochrane Systematic Reviews, 30-Nov-2022
Cardiac surgery is performed worldwide. Most types of cardiac surgery are performed using cardiopulmonary bypass (CPB). Cardiac surgery performed with CPB is associated with morbidities. CPB needs an extracorporeal circulation that replaces the heart and - High versus low dose of initial thyroid hormone replacement for congenital hypothyroidism
Cochrane Systematic Reviews, 20-Jan-2009
Congenital hypothyroidism (CHT) affects approximately one in 3000 to 4000 infants. CHT is one of the most common preventable causes of learning difficulties. Optimal management of CHT requires early diagnosis and prompt treatment to avoid abnormal neurode - High versus low medium chain triglyceride content of formula for promoting short‐term growth of preterm infants
Cochrane Systematic Reviews, 23-Feb-2021
In-hospital growth of preterm infants remains a challenge in clinical practice. The high nutrient demands of preterm infants often lead to growth faltering. For preterm infants who cannot be fed maternal or donor breast milk or may require supplementation - High versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute lung injury and acute respiratory distress syndrome
Cochrane Systematic Reviews, 30-Mar-2021
In patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), mortality remains high. These patients require mechanical ventilation, which has been associated with ventilator-induced lung injury. High levels of positive end-expi - High versus low‐added sugar consumption for the primary prevention of cardiovascular disease
Cochrane Systematic Reviews, 5-Jan-2022
High intake of added sugar have been suggested to impact the risk for cardiovascular disease (CVD). Knowledge on the subject can contribute to preventing CVD. - High versus standard volume enteral feeds to promote growth in preterm or low birth weight infants
Cochrane Systematic Reviews, 12-Mar-2021
Human milk is the best enteral nutrition for preterm infants. However, human milk, given at standard recommended volumes, is not adequate to meet the protein, energy, and other nutrient requirements of preterm or low birth weight infants. One strategy tha - High-carbohydrate, high-protein, low-fat versus low-carbohydrate, high-protein, high-fat enteral feeds for burns
Cochrane Systematic Reviews, 18-Jan-2012
Severe burn injuries increase patients' metabolic needs. Aggressive high-protein enteral feeding is used in the post-burn period to improve recovery and healing. - High‐dose chemotherapy and autologous bone marrow or stem cell transplantation versus conventional chemotherapy for women with early poor prognosis breast cancer
Cochrane Systematic Reviews, 20-May-2016
Overall survival rates are disappointing for women with early poor prognosis breast cancer. Autologous transplantation of bone marrow or peripheral stem cells (in which the woman is both donor and recipient) has been considered a promising technique becau - High‐dose chemotherapy and autologous bone marrow or stem cell transplantation versus conventional chemotherapy for women with metastatic breast cancer
Cochrane Systematic Reviews, 20-Jul-2005
Although metastatic breast cancer is often responsive to conventional chemotherapy, it remains ultimately incurable. Autologous transplantation of bone marrow or peripheral stem cells (in which the patient is both donor and recipient) has been considered - High‐dose chemotherapy and autologous haematopoietic stem cell rescue for children with high‐risk neuroblastoma
Cochrane Systematic Reviews, 5-Oct-2015
Despite the development of new treatment options, the prognosis of high-risk neuroblastoma patients is still poor; more than half of patients experience disease recurrence. High-dose chemotherapy and haematopoietic stem cell rescue (i.e. myeloablative the - High‐dose chemotherapy followed by autologous haematopoietic cell transplantation for children, adolescents, and young adults with first recurrence of Ewing sarcoma
Cochrane Systematic Reviews, 2-Sep-2021
Ewing sarcoma is a solid tumour, which is the second most common primary bone malignancy in children, often occurring in the long bones and pelvis. An incidence rate of 4.5 per million a year is reported, with a peak incidence of 11 per million at the age - High‐dose chemotherapy followed by autologous haematopoietic cell transplantation for children, adolescents, and young adults with primary metastatic Ewing sarcoma
Cochrane Systematic Reviews, 2-Sep-2021
Ewing sarcomas are solid tumours of the bone and soft tissue, that usually affect children, adolescents, and young adults. The incidence is about three cases per million a year, with a peak incidence at 12 years of age. Metastatic disease is detected in a - High-dose chemotherapy followed by autologous stem cell transplantation for patients with relapsed/refractory Hodgkin lymphoma
Cochrane Systematic Reviews, 19-Jun-2013
Hodgkin lymphoma (HL) is one of the most common malignancies in young adults and has become curable for the majority of patients, even in advanced stage. After first-line therapy, 15% to 20% do not respond to treatment and relapse. For those patients, hig - High-dose chemotherapy for children and young adults with stage IV rhabdomyosarcoma
Cochrane Systematic Reviews, 8-Nov-2010
Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood. Prognosis for patients with metastatic disease has not improved significantly in the past decades. High-dose chemotherapy (HDC) seems to be an attractive option to treat minimal residua - High-dose chemotherapy with autologous stem cell transplantation in the first line treatment of aggressive Non-Hodgkin Lymphoma (NHL) in adults
Cochrane Systematic Reviews, 2-Apr-2011
High-dose chemotherapy with autologous stem cell support (HDT) has been proven effective in relapsed aggressive non-Hodgkin lymphoma (NHL). However, conflicting results of HDT as part of first-line treatment have been reported in randomised controlled tri - High‐dose opioids for chronic non‐cancer pain: an overview of Cochrane Reviews
Cochrane Systematic Reviews, 30-Oct-2017
Chronic pain is typically described as pain on most days for at least three months. Chronic non-cancer pain (CNCP) is any chronic pain that is not due to a malignancy. Chronic non-cancer pain in adults is a common and complex clinical issue where opioids - High-dose therapy with autologous stem cell transplantation versus chemotherapy or immuno-chemotherapy for follicular lymphoma in adults
Cochrane Systematic Reviews, 15-Nov-2011
Follicular lymphoma (FL) is the most common indolent and second most common Non-Hodgkin`s lymphoma (NHL) in the Western world. Standard treatment usually includes rituximab and chemotherapy. High-dose therapy (HDT) followed by autologous stem cell transpl - High‐dose versus low‐dose oxytocin for augmentation of delayed labour
Cochrane Systematic Reviews, 13-Jul-2013
A major cause of failure to achieve spontaneous vaginal birth is delay in labour due to presumed inefficient uterine action. Oxytocin is given to increase contractions and high-dose regimens may potentially increase the number of spontaneous vaginal birth
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