Showing 321-340 of 374 for: Cochrane Systematic Reviews > Oncology 
- Splenectomy versus conservative management for acute sequestration crises in people with sickle cell disease
Cochrane Systematic Reviews, 7-Nov-2017
Acute splenic sequestration crises are a complication of sickle cell disease, with high mortality rates and frequent recurrence in survivors of first attacks. Splenectomy and blood transfusion, with their consequences, are the mainstay of long-term manage
- Stapled versus handsewn methods for colorectal anastomosis surgery
Cochrane Systematic Reviews, 18-Jan-2012
Previous systematic reviews comparing stapled and handsewn colorectal anastomosis that are available in the medical literature have not shown either technique to be superior. An update of this systematic review was performed to find out if there are any d
- Stapled versus handsewn methods for ileocolic anastomoses
Cochrane Systematic Reviews, 13-Jul-2011
Ileocolic anastomoses are commonly performed for right-sided colon cancer and Crohn's disease. The anastomosis may be constructed using a linear cutter stapler or by suturing. Individual trials comparing stapled versus handsewn ileocolic anastomoses have
- Statins and fibrates for preventing melanoma
Cochrane Systematic Reviews, 17-Nov-2014
Effective treatment for advanced melanoma is lacking. While no drug therapy currently exists for prevention of melanoma, in vitro, case-control, and animal model evidence suggest that lipid-lowering medications, commonly taken for high cholesterol, might
- Steroids, radiotherapy, chemotherapy and stents for superior vena caval obstruction in carcinoma of the bronchus
Cochrane Systematic Reviews, 9-Mar-2015
Superior vena caval obstruction (SVCO) is an uncommon manifestation of carcinoma of the bronchus characterised by neck swelling and distended veins over the chest. Treatment options include radiotherapy, chemotherapy, steroids and insertion of an expandab
- Strategies for detecting colon cancer and/or dysplasia in patients with inflammatory bowel disease
Cochrane Systematic Reviews, 17-Jul-2008
Patients with longstanding ulcerative colitis and colonic Crohn's disease have an increased risk of colorectal cancer compared with the general population. This review assesses the evidence that endoscopic surveillance may prolong life by allowing earlier
- Strategies for increasing the participation of women in community breast cancer screening
Cochrane Systematic Reviews, 15-Oct-2008
Strategies for reducing breast cancer mortality in western countries have focused on screening, at least for women aged 50 to 69 years. One of the requirements of any community screening program is to achieve a high participation rate, which is related to
- Supportive care for patients with gastrointestinal cancer
Cochrane Systematic Reviews, 6-Oct-2009
This review is an update of a previously published update review in The Cochrane Database of Systematic Reviews (Issue 4, 2006) on this topic. No new studies have been identified from the update search and the conclusions are not altered. Supportive care
- Surgery for cervical intraepithelial neoplasia
Cochrane Systematic Reviews, 2-Dec-2013
Cervical intraepithelial neoplasia (CIN) is the most common pre-malignant lesion. Atypical squamous changes occur in the transformation zone of the cervix with mild, moderate or severe changes described by their depth (CIN 1, 2 or 3). Cervical intraepithe
- Surgery for local and locally advanced non-small cell lung cancer
Cochrane Systematic Reviews, 14-Mar-2010
Surgical resection (usually lobectomy) is considered the treatment of choice for many individuals with early stage non-small cell lung cancer (NSCLC) . However much of the evidence is observational.
- Surgery for the resolution of symptoms in malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer
Cochrane Systematic Reviews, 21-Mar-2016
This is an update of the original Cochrane review published in Issue 4, 2000. Intestinal obstruction commonly occurs in progressive advanced gynaecological and gastrointestinal cancers. Management of these patients is difficult due to the patients' deteri
- Surgery versus primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus)
Cochrane Systematic Reviews, 18-May-2014
Several studies have evaluated the clinical effectiveness of endocrine therapy alone in women aged 70 years or over with operable breast cancer and who are fit for surgery.
- Surgery versus radiosurgery for patients with a solitary brain metastasis from non-small cell lung cancer
Cochrane Systematic Reviews, 22-Aug-2014
Non-small cell lung cancer is one of the leading causes of death in developed countries. Brain metastases are often seen in non-small cell lung cancer patients and although they are frequently multiple, a subset of patients with a solitary brain metastasi
- Surgery versus radiotherapy for muscle invasive bladder cancer
Cochrane Systematic Reviews, 5-Mar-2012
Muscle invasive bladder cancer is a serious clinical problem and is fatal for the majority of patients. Alternative treatments for this condition are radical cystectomy or radical radiotherapy. The choice of treatment varies according to the resident coun
- Surgical approach to hysterectomy for benign gynaecological disease
Cochrane Systematic Reviews, 10-Aug-2015
The four approaches to hysterectomy for benign disease are abdominal hysterectomy (AH), vaginal hysterectomy (VH), laparoscopic hysterectomy (LH) and robotic-assisted hysterectomy (RH).
- Surgical excision margins for primary cutaneous melanoma
Cochrane Systematic Reviews, 8-Nov-2009
Cutaneous melanoma accounts for 75% of skin cancer deaths. Standard treatment is surgical excision with a safety margin some distance from the borders of the primary tumour. The purpose of the safety margin is to remove both the complete primary tumour an
- Surgical interventions for early squamous cell carcinoma of the vulva
Cochrane Systematic Reviews, 3-Jul-2014
Radical surgery has been standard treatment for patients with early vulvar cancer since the mid 1900s. Survival figures are excellent, but complication rates are high. Since 1980, surgery has become more individualised in order to decrease complications i
- Surgical interventions for high-grade vulval intraepithelial neoplasia
Cochrane Systematic Reviews, 30-Dec-2015
This is an updated version of an original Cochrane review published in The Cochrane Library, 2011, Issue 1.
- Surgical management for upper urinary tract transitional cell carcinoma
Cochrane Systematic Reviews, 24-Feb-2011
Upper tract transitional cell carcinomas (TCC) are uncommon and aggressive tumours. There are a number of surgical approaches to manage this condition including open radical nephroureterectomy and laparoscopic procedures.
- Surgical management of localised renal cell carcinoma
Cochrane Systematic Reviews, 5-Mar-2016
Surgical excision remains the core to the management of localised renal cancer and several studies have evaluated the safety and clinical effectiveness of laparoscopic surgery and other recently introduced interventions for the localised disease.
