- Hydergine for dementia
Cochrane Systematic Reviews, 24-Jul-2000
Currently hydergine is used almost exclusively for treating patients with either dementia, or 'age-related' cognitive symptoms. Since the early 1980s there have been over a dozen more clinical trials, yet hydergine's efficacy remains uncertain. Although p - Hydralazine for essential hypertension
Cochrane Systematic Reviews, 4-Oct-2011
Hypertension is associated with an increased risk of stroke, myocardial infarction and congestive heart failure. Hydralazine is a direct-acting vasodilator which has been used for the treatment of hypertension since the 1950's. Although it has largely bee - Hydralazine in infants with persistent hypoxemic respiratory failure
Cochrane Systematic Reviews, 7-Dec-2012
Most deaths of infants with chronic lung disease (CLD) are caused by respiratory failure, unremitting pulmonary artery hypertension (PAH) with cor pulmonale, or infection. Although the exact prevalence of PAH in infants with CLD is unknown, infants with C - Hydration for treatment of preterm labour
Cochrane Systematic Reviews, 19-Dec-2013
Hydration has been proposed as a treatment for women with preterm labour. Theoretically, hydration may reduce uterine contractility by increasing uterine blood flow and by decreasing pituitary secretion of antidiuretic hormone and oxytocin. - Hydrocolloid dressings for healing diabetic foot ulcers
Cochrane Systematic Reviews, 6-Aug-2013
Foot ulcers in people with diabetes are a prevalent and serious global health issue. Wound dressings are regarded as important components of ulcer treatment, with clinicians and patients having many different types to choose from including hydrocolloid dr - Hydrogel dressings for healing diabetic foot ulcers
Cochrane Systematic Reviews, 12-Jul-2013
Foot ulcers in people with diabetes are a prevalent and serious global health issue. Dressings form a key part of ulcer treatment, with clinicians and patients having many different types to choose from including hydrogel dressings. A clear and current ov - Hydrogel dressings for treating pressure ulcers
Cochrane Systematic Reviews, 11-Feb-2015
Pressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Dressings are widely used to treat pressure ulcers and there are many different dressing options - Hydrogel dressings for venous leg ulcers
Cochrane Systematic Reviews, 5-Aug-2022
Venous leg ulcers are a chronic health problem that cause considerable economic impact and affect quality of life for those who have them. Primary wound contact dressings are usually applied to ulcers beneath compression therapy to aid healing, promote co - Hydromorphone for acute and chronic pain
Cochrane Systematic Reviews, 25-Oct-2013
This is an updated version of the original review, published in Issue 1, 2002. Some patients with severe cancer pain either do not achieve adequate analgesia with morphine, or suffer intolerable toxicity. For these patients alternatives such as hydromorph - Hydromorphone for cancer pain
Cochrane Systematic Reviews, 5-Aug-2021
This is an update of the original Cochrane Review first published in Issue 10, 2016. For people with advanced cancer, the prevalence of pain can be as high as 90%. Cancer pain is a distressing symptom that tends to worsen as the disease progresses. Eviden - Hydromorphone for neuropathic pain in adults
Cochrane Systematic Reviews, 24-May-2016
Opioid drugs, including hydromorphone, are commonly used to treat neuropathic pain, and are considered effective by some professionals. Most reviews have examined all opioids together. This review sought evidence specifically for hydromorphone, at any dos - Hydrosurgical debridement versus conventional surgical debridement for acute partial‐thickness burns
Cochrane Systematic Reviews, 3-Sep-2020
Burn injuries are the fourth most common traumatic injury, causing an estimated 180,000 deaths annually worldwide. Superficial burns can be managed with dressings alone, but deeper burns or those that fail to heal promptly are usually treated surgically. - Hydroxyethyl starch (HES) versus other fluid therapies: effects on kidney function
Cochrane Systematic Reviews, 17-Jul-2013
Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume, yet they have been increasingly associated with adverse effects on kidney function. This is an update of a Cochrane review first publ - Hydroxyurea (hydroxycarbamide) for sickle cell disease
Cochrane Systematic Reviews, 1-Sep-2022
Sickle cell disease (SCD) is one of the most common inherited diseases worldwide. It is associated with lifelong morbidity and a reduced life expectancy. Hydroxyurea (hydroxycarbamide), an oral chemotherapeutic drug, ameliorates some of the clinical probl - Hydroxyurea (hydroxycarbamide) for transfusion‐dependent β‐thalassaemia
Cochrane Systematic Reviews, 16-Mar-2019
Hydroxyurea (hydroxycarbamide) promotes the production of foetal haemoglobin (HbF) by reactivating gamma-genes. Evidence has shown clinical benefits of hydroxyurea in people with sickle cell anemia; however, only a few studies have assessed this treatment - Hydroxyurea for reducing blood transfusion in non-transfusion dependent beta thalassaemias
Cochrane Systematic Reviews, 8-Aug-2016
Non-transfusion dependent beta thalassaemia is a subset of inherited haemoglobin disorders characterised by reduced production of the beta globin chain of the haemoglobin molecule leading to anaemia of varying severity. Although blood transfusion is not a - Hydroxyzine for generalised anxiety disorder
Cochrane Systematic Reviews, 9-Nov-2010
Generalised anxiety disorder (GAD) is a common chronic long-term psychiatric disorder, particularly frequent in primary care. There are several treatment options available, both non-pharmacological (i.e. cognitive behavioral therapy) and pharmacological. - Hygiene and emollient interventions for maintaining skin integrity in older people in hospital and residential care settings
Cochrane Systematic Reviews, 23-Jan-2020
Ageing has a degenerative effect on the skin, leaving it more vulnerable to damage. Hygiene and emollient interventions may help maintain skin integrity in older people in hospital and residential care settings; however, at present, most care is based on - Hyperbaric oxygen as an adjuvant treatment for malignant otitis externa
Cochrane Systematic Reviews, 31-May-2013
Malignant, or necrotising, otitis externa is a potentially fatal infection of the external ear canal and surrounding soft tissue and bone. It may be complicated by involvement of cranial nerves, principally the facial nerves and the contents of the jugula - Hyperbaric oxygen for carbon monoxide poisoning
Cochrane Systematic Reviews, 13-Apr-2011
Poisoning with carbon monoxide (CO) remains an important cause of accidental and intentional injury worldwide. Several unblinded non-randomized trials have suggested that the use of hyperbaric oxygen (HBO) prevents the development of neurological sequelae
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