- Immunosuppressive agents for treating IgA nephropathy
Cochrane Systematic Reviews, 12-Mar-2020
IgA nephropathy is the most common glomerulonephritis world-wide. IgA nephropathy causes end-stage kidney disease (ESKD) in 15% to 20% of affected patients within 10 years and in 30% to 40% of patients within 20 years from the onset of disease. This is an - Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis
Cochrane Systematic Reviews, 19-Jul-2006
Immunosuppressive and cytotoxic agents have been used as both an alternative to oral corticosteroids, and as a means of maintaining a low dose of steroids in the treatment of pulmonary sarcoidosis. - Immunosuppressive drug therapy for preventing rejection following lung transplantation in cystic fibrosis
Cochrane Systematic Reviews, 19-Jun-2018
For people with cystic fibrosis and advanced pulmonary damage, lung transplantation is an available and viable option. However, graft rejection is an important potential consequence after lung transplantation. Immunosuppressive therapy is needed to preven - Immunosuppressive T-cell antibody induction for heart transplant recipients
Cochrane Systematic Reviews, 1-Dec-2013
Heart transplantation has become a valuable and well-accepted treatment option for end-stage heart failure. Rejection of the transplanted heart by the recipient's body is a risk to the success of the procedure, and life-long immunosuppression is necessary - Immunosuppressive treatment for non-systemic vasculitic neuropathy
Cochrane Systematic Reviews, 3-Apr-2013
Non-systemic vasculitic neuropathy is a rare disabling disease that usually has a subacute onset of progressive or relapsing-remitting sensory or sensorimotor deficits. Asymmetry, pain and weakness are key features. The diagnosis can only be made by exclu - Immunosuppressive treatment for primary membranous nephropathy in adults with nephrotic syndrome
Cochrane Systematic Reviews, 15-Nov-2021
Primary membranous nephropathy (PMN) is a common cause of nephrotic syndrome in adults. Without treatment, approximately 30% of patients will experience spontaneous remission and one third will have persistent proteinuria. Approximately one-third of patie - Immunosuppressive treatment for proliferative lupus nephritis
Cochrane Systematic Reviews, 29-Jun-2018
Cyclophosphamide, in combination with corticosteroids, has been first-line treatment for inducing disease remission for proliferative lupus nephritis, reducing death at five years from over 50% in the 1950s and 1960s to less than 10% in recent years. Seve - Immunotherapy (excluding checkpoint inhibitors) for stage I to III non‐small cell lung cancer treated with surgery or radiotherapy with curative intent
Cochrane Systematic Reviews, 6-Dec-2021
Non-small cell lung cancer (NSCLC) is the most common lung cancer, accounting for approximately 80% to 85% of all cases. For people with localised NSCLC (stages I to III), it has been speculated that immunotherapy may be helpful for reducing postoperative - Immunotherapy (oral and sublingual) for food allergy to fruits
Cochrane Systematic Reviews, 9-Nov-2015
Food allergy is an abnormal immunological response following exposure (usually ingestion) to a food. Elimination of the allergen is the principle treatment for food allergy, including allergy to fruit. Accidental ingestion of allergenic foods can result i - Immunotherapy for advanced renal cell cancer
Cochrane Systematic Reviews, 29-Dec-2015
The course of advanced renal cell carcinoma is extremely variable, ranging from spontaneous remission to disease progression refractory to chemotherapy. Immunotherapy has held promise of improved outcomes based on uncontrolled studies and randomized contr - Immunotherapy for diabetic amyotrophy
Cochrane Systematic Reviews, 26-Jul-2017
People with diabetes mellitus (DM) sometimes present with acute or subacute, progressive, asymmetrical pain and weakness of the proximal lower limb muscles. The various names for the condition include diabetic amyotrophy, diabetic lumbosacral radiculoplex - Immunotherapy for idiopathic lumbosacral plexopathy
Cochrane Systematic Reviews, 21-Dec-2013
Idiopathic lumbosacral plexopathy (ILSP), also called lumbosacral plexitis or non-diabetic lumbosacral (radiculo)plexus neuropathy is a rare clinical entity. The core features are (sub)acute, severe, asymmetrical leg pain, followed by asymmetrical multifo - Immunotherapy for IgM anti‐myelin‐associated glycoprotein paraprotein‐associated peripheral neuropathies
Cochrane Systematic Reviews, 4-Oct-2016
Serum monoclonal anti-myelin-associated glycoprotein (anti-MAG) antibodies may be pathogenic in some people with immunoglobulin M (IgM) paraprotein and demyelinating neuropathy. Immunotherapies aimed at reducing the level of these antibodies might be expe - Immunotherapy for metastatic renal cell carcinoma
Cochrane Systematic Reviews, 15-May-2017
Since the mid-2000s, the field of metastatic renal cell carcinoma (mRCC) has experienced a paradigm shift from non-specific therapy with broad-acting cytokines to specific regimens, which directly target the cancer, the tumour microenvironment, or both. - Immunotherapy for recurrent miscarriage
Cochrane Systematic Reviews, 21-Oct-2014
Because immunological aberrations might be the cause of miscarriage in some women, several immunotherapies have been used to treat women with otherwise unexplained recurrent pregnancy loss. - Impact of diagnostic strategies for tuberculosis using lateral flow urine lipoarabinomannan assay in people living with HIV
Cochrane Systematic Reviews, 20-Aug-2021
Tuberculosis is the primary cause of hospital admission in people living with HIV, and the likelihood of death in the hospital is unacceptably high. The Alere Determine TB LAM Ag test (AlereLAM) is a point-of-care test and the only lateral flow lipoarabin - Impact of Haemophilus influenzae type B (Hib) and viral influenza vaccinations in pregnancy for improving maternal, neonatal and infant health outcomes
Cochrane Systematic Reviews, 5-Jun-2015
Infections during pregnancy confers increased risk of maternal and perinatal morbidity and mortality. However, the case for advocating Haemophilus influenzae type B (Hib) and viral Influenza vaccinations in pregnancy is still debatable. - Impact of institutional smoking bans on reducing harms and secondhand smoke exposure
Cochrane Systematic Reviews, 25-May-2016
Smoking bans or restrictions can assist in eliminating nonsmokers' exposure to the dangers of secondhand smoke and can reduce tobacco consumption amongst smokers themselves. Evidence exists identifying the impact of tobacco control regulations and interve - Impact of low‐dose computed tomography (LDCT) screening on lung cancer‐related mortality
Cochrane Systematic Reviews, 3-Aug-2022
Lung cancer is the most common cause of cancer-related death in the world, however lung cancer screening has not been implemented in most countries at a population level. A previous Cochrane Review found limited evidence for the effectiveness of lung canc - Impact of medication reconciliation for improving transitions of care
Cochrane Systematic Reviews, 23-Aug-2018
Transitional care provides for the continuity of care as patients move between different stages and settings of care. Medication discrepancies arising at care transitions have been reported as prevalent and are linked with adverse drug events (ADEs) (e.g.
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