Showing 341-360 of 746 for: Cochrane Systematic Reviews > Pharmacotherapeutics 
- Immunoglobulin for alloimmune hemolytic disease in neonates
Cochrane Systematic Reviews, 18-Mar-2018
Exchange transfusion and phototherapy have traditionally been used to treat jaundice and avoid the associated neurological complications. Because of the risks and burdens of exchange transfusion, intravenous immunoglobulin (IVIg) has been suggested as an
- Immunoglobulin for multifocal motor neuropathy
Cochrane Systematic Reviews, 11-Jan-2022
Multifocal motor neuropathy (MMN) is a rare, probably immune-mediated disorder characterised by slowly progressive, asymmetric, distal weakness of one or more limbs with no objective loss of sensation. It may cause prolonged periods of disability. Treatme
- Immunoglobulins, vaccines or interferon for preventing cytomegalovirus disease in solid organ transplant recipients
Cochrane Systematic Reviews, 17-Mar-2010
Cytomegalovirus (CMV) is the most common virus causing disease and death in solid organ transplant recipients during the first six months post-transplant. Previous systematic reviews have demonstrated the efficacy of antiviral medications used prophylacti
- Immunosuppressive agents for myasthenia gravis
Cochrane Systematic Reviews, 2-Nov-2008
The benefits of different immunosuppressants for myasthenia gravis (MG) are unclear.
- Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis
Cochrane Systematic Reviews, 19-Jul-2006
Immunosuppressive and cytotoxic agents have been used as both an alternative to oral corticosteroids, and as a means of maintaining a low dose of steroids in the treatment of pulmonary sarcoidosis.
- Immunotherapy for IgM anti‐myelin‐associated glycoprotein paraprotein‐associated peripheral neuropathies
Cochrane Systematic Reviews, 4-Oct-2016
Serum monoclonal anti-myelin-associated glycoprotein (anti-MAG) antibodies may be pathogenic in some people with immunoglobulin M (IgM) paraprotein and demyelinating neuropathy. Immunotherapies aimed at reducing the level of these antibodies might be expe
- Infusion techniques for peripheral arterial thrombolysis
Cochrane Systematic Reviews, 17-Nov-2021
Acute limb ischaemia usually is caused by a blood clot blocking an artery or a bypass graft. Severe acute ischaemia will lead to irreversible damage to muscles and nerves if blood flow is not restored in a few hours. Once irreversible damage occurs, amput
- Inhaled beta2‐agonists for asthma in mechanically ventilated patients
Cochrane Systematic Reviews, 23-Oct-2001
A small number of patients with acute severe asthma require intubation and positive pressure ventilation. The beneficial effects of inhaled bronchodilators on acute asthma in spontaneously breathing subjects are well established, but there remain importan
- Inhaled beta2-agonists for non-specific chronic cough in children
Cochrane Systematic Reviews, 29-Mar-2009
The pathophysiology of so called 'cough variant asthma' has not received a great deal of research interest and opinion lies divided as to whether it is really asthma or not. The proponents of cough variant asthma suggest a therapeutic trial of medications
- Inhaled bronchodilators for cystic fibrosis
Cochrane Systematic Reviews, 11-Feb-2016
Recurrent wheeze and breathlessness are common in people with cystic fibrosis, and bronchodilators are commonly prescribed. Despite their wide-scale and often long-term use, there is limited objective evidence about their efficacy in cystic fibrosis (CF).
- Inhaled corticosteroid effects on bone metabolism in asthma and mild chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 21-Jan-2002
Inhaled corticosteroids form the main therapy for asthma, but there is increasing concern about the potential systematic effects of long-term inhaled corticosteroids including their effect on bone metabolism and bone loss.
- Inhaled corticosteroids compared to placebo for prevention of exercise induced bronchoconstriction
Cochrane Systematic Reviews, 18-Jul-2007
The pathogenesis of exercise induced bronchoconstriction is likely multifactorial and is not completely understood. Inflammation plays an important role in the pathogenesis of exercise induced bronchoconstriction in asthmatic subjects but the evidence see
- Inhaled corticosteroids for bronchiectasis
Cochrane Systematic Reviews, 16-May-2018
Bronchiectasis is being increasingly diagnosed and recognised as an important contributor to chronic lung disease in both adults and children in high- and low-income countries. It is characterised by irreversible dilatation of airways and is generally ass
- Inhaled corticosteroids for cystic fibrosis
Cochrane Systematic Reviews, 4-Jul-2019
The reduction of lung inflammation is one of the goals of cystic fibrosis therapy. Inhaled corticosteroids are often used in this respect to treat children and adults with cystic fibrosis. The rationale for this is their potential to reduce lung damage ar
- Inhaled corticosteroids for non-specific chronic cough in children
Cochrane Systematic Reviews, 29-Mar-2009
Cough in isolation of other clinical features is known as non-specific cough, which has been defined as non-productive cough in the absence of identifiable respiratory disease or any known aetiology. In children with non-specific cough the possibility of
- Inhaled corticosteroids for stable chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 25-Aug-2016
The role of inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease (COPD) has been the subject of much controversy. Major international guidelines recommend selective use of ICS. Recently published meta-analyses have reported conflicting f
- Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma
Cochrane Systematic Reviews, 19-Apr-2006
Inhaled corticosteroids (ICS) and sodium cromoglycate (SCG) have become established as effective controller medications for children and adults with asthma, but their relative efficacy is not clear.
- Inhaled insulin in diabetes mellitus
Cochrane Systematic Reviews, 8-Oct-2008
Insulin therapy often relies on multiple daily injections of insulin. However this is a considerable burden to many people with diabetes and adherence to such an insulin regimen can be difficult to maintain, hence compromising optimal glycaemic control. A
- Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults
Cochrane Systematic Reviews, 27-Jun-2016
Acute hypoxaemic respiratory failure (AHRF) and mostly acute respiratory distress syndrome (ARDS) are critical conditions. AHRF results from several systemic conditions and is associated with high mortality and morbidity in individuals of all ages. Inhale
- Inhaled nitric oxide for respiratory failure in preterm infants
Cochrane Systematic Reviews, 3-Jan-2017
Inhaled nitric oxide (iNO) is effective in term infants with hypoxic respiratory failure. The pathophysiology of respiratory failure and the potential risks of iNO differ substantially in preterm infants, necessitating specific study in this population.
