- Inhaled nitric oxide for treating pain crises in people with sickle cell disease
Cochrane Systematic Reviews, 8-Jul-2022
In people with sickle cell disease, sickled red blood cells cause the occlusion of small blood vessels, which presents as episodes of severe pain known as pain crises or vaso-occlusive crises. The pain can occur in the bones, chest, or other parts of the - Inhaled non‐steroid anti‐inflammatories for children and adults with bronchiectasis
Cochrane Systematic Reviews, 27-Jan-2016
Chronic neutrophilic inflammation, in both the presence and absence of infection, is a feature of bronchiectasis in adults and children. The anti-inflammatory properties of non-steroid anti-inflammatory drugs (NSAIDs) may be beneficial in reducing airway - Inhaled short acting beta2‐agonist use in chronic asthma: regular versus as needed treatment
Cochrane Systematic Reviews, 20-Jan-2003
Inhaled short-acting beta-2 agonists are the major class of bronchodilators used for relief of symptoms in asthma. There has been concern that excessive uncontrolled use of beta-2 agonists might have contributed to rises in asthma mortality seen in some c - Inhaled short‐acting beta2‐agonists versus ipratropium for acute exacerbations of chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 22-Jan-2001
Inhaled short acting beta2 adrenergic agonists and ipratropium bromide are both used in the treatment of acute exacerbations of chronic obstructive pulmonary disease. - Inhaled sodium cromoglycate for asthma in children
Cochrane Systematic Reviews, 8-Oct-2008
Sodium cromoglycate has been recommended as maintenance treatment for childhood asthma for many years. Its use has decreased since 1990, when inhaled corticosteroids became popular, but it is still used in many countries. - Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 10-Mar-2014
Inhaled corticosteroids (ICS) are anti-inflammatory drugs that have proven benefits for people with worsening symptoms of chronic obstructive pulmonary disease (COPD) and repeated exacerbations. They are commonly used as combination inhalers with long-act - Inhaled steroids for acute asthma following emergency department discharge
Cochrane Systematic Reviews, 12-Dec-2012
Patients with acute asthma treated in the emergency department (ED) are frequently treated with inhaled beta2-agonists and systemic corticosteroids after discharge. The use of inhaled corticosteroids (ICS) following discharge may also be beneficial in imp - Inhaled steroids for episodic viral wheeze of childhood
Cochrane Systematic Reviews, 24-Jan-2000
Recurrent episodic wheeze in association with viral upper respiratory tract infection (URTI) is a specific clinical illness distinct from persistent atopic asthma. - Inhaled steroids with and without regular formoterol for asthma: serious adverse events
Cochrane Systematic Reviews, 25-Sep-2019
Epidemiological evidence has suggested a link between beta2-agonists and increases in asthma mortality. There has been much debate about whether regular (daily) long-acting beta2-agonists (LABA) are safe when used in combination with inhaled corticosteroi - Inhaled steroids with and without regular salmeterol for asthma: serious adverse events
Cochrane Systematic Reviews, 3-Dec-2018
Epidemiological evidence has suggested a link between use of beta2-agonists and increased asthma mortality. Much debate has surrounded possible causal links for this association, and whether regular (daily) long-acting beta2-agonists (LABAs) are safe, par - Inhaled versus oral steroids for adults with chronic asthma
Cochrane Systematic Reviews, 22-Jan-2001
Steroids are a common treatment of chronic asthma as a maintenance therapy in both developed and developing countries across the world. The cost of inhaled steroids means that in developing countries their availability is limited, leading to poorly contro - Inhaled versus systemic corticosteroids for preventing bronchopulmonary dysplasia in ventilated very low birth weight preterm neonates
Cochrane Systematic Reviews, 17-Oct-2017
Bronchopulmonary dysplasia (BPD) remains an important cause of mortality and morbidity in preterm infants and inflammation plays a significant role in its pathogenesis. The use of inhaled corticosteroids may modulate the inflammatory process without conco - Inhaled versus systemic corticosteroids for the treatment of bronchopulmonary dysplasia in ventilated very low birth weight preterm infants
Cochrane Systematic Reviews, 16-Oct-2017
This is an update of a review published in 2012. A related review "Inhaled versus systemic corticosteroids for preventing bronchopulmonary dysplasia in ventilated very low birth weight preterm neonates" has been updated as well. Bronchopulmonary dysplasia - In‐hospital care pathways for stroke
Cochrane Systematic Reviews, 18-Oct-2004
Stroke care pathways have the potential to promote organised and efficient patient care that is based on best evidence and guidelines, but evidence to support their use is unclear. - Initial arch wires used in orthodontic treatment with fixed appliances
Cochrane Systematic Reviews, 31-Jul-2018
Initial arch wires are the first arch wires to be inserted into the fixed appliance at the beginning of orthodontic treatment and are used mainly for the alignment of teeth by correcting crowding and rotations. With a number of different types of orthodon - Initial management strategies for dyspepsia
Cochrane Systematic Reviews, 23-Jul-2009
This review considers management strategies (combinations of initial investigation and empirical treatments) for dyspeptic patients. Dyspepsia was defined to include both epigastric pain and heartburn. - Injectable gold for rheumatoid arthritis
Cochrane Systematic Reviews, 20-Oct-1997
Gold compounds have been used in several conditions affecting man since the 18th century (tuberculosis, lupus vulgaris, bacterial endocarditis, etc.) however, in the past decade the use of injectable gold for rheumatoid arthritis has markedly declined, an - Injectable local anaesthetic agents for dental anaesthesia
Cochrane Systematic Reviews, 10-Jul-2018
Pain during dental treatment, which is a common fear of patients, can be controlled successfully by local anaesthetic. Several different local anaesthetic formulations and techniques are available to dentists. - Injected corticosteroids for treating plantar heel pain in adults
Cochrane Systematic Reviews, 11-Jun-2017
Plantar heel pain, commonly resulting from plantar fasciitis, often results in significant morbidity. Treatment options include nonsteroidal anti-inflammatory drugs (NSAIDs), orthoses, physical therapy, physical agents (e.g. extracorporeal shock wave ther - Injection allergen immunotherapy for asthma
Cochrane Systematic Reviews, 28-Jun-2010
Allergen specific immunotherapy has long been a controversial treatment for asthma. Although beneficial effects upon clinically relevant outcomes have been demonstrated in randomised controlled trials, there remains a risk of severe and sometimes fatal an
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