Showing 361-374 of 374 for: Cochrane Systematic Reviews > Oncology 
- Trastuzumab containing regimens for early breast cancer
Cochrane Systematic Reviews, 12-Mar-2012
Approximately one-fifth of women who develop early breast cancer have HER2-positive tumours, which if untreated, have a worse prognosis than HER2-negative tumours. Trastuzumab is a selective treatment targeting the HER2 pathway. Although the results on ef
- Treatment of severe or progressive Kaposi's sarcoma in HIV-infected adults
Cochrane Systematic Reviews, 29-Aug-2014
Kaposi's sarcoma remains the most common cancer in Sub-Saharan Africa and the second most common cancer in HIV-infected patients worldwide. Since the introduction of highly active antiretroviral therapy (HAART), there has been a decline in its incidence.
- Ultra‐radical (extensive) surgery versus standard surgery for the primary cytoreduction of advanced epithelial ovarian cancer
Cochrane Systematic Reviews, 30-Aug-2022
Ovarian cancer is the seventh most common cancer among women and the leading cause of death in women with gynaecological malignancies. Opinions differ regarding the role of ultra-radical (extensive) cytoreductive surgery in ovarian cancer treatment.
- Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer
Cochrane Systematic Reviews, 7-Aug-2014
Tumour lysis syndrome (TLS) is a serious complication of malignancies and can result in renal failure or death. Preliminary reports suggest that urate oxidase is effective in reducing serum uric acid, the build-up of which causes TLS. It is uncertain whet
- Urinary diversion and bladder reconstruction/replacement using intestinal segments for intractable incontinence or following cystectomy
Cochrane Systematic Reviews, 18-Jan-2012
Surgery performed to improve or replace the function of the diseased urinary bladder has been carried out for over a century. Main reasons for improving or replacing the function of the urinary bladder are bladder cancer, neurogenic bladder dysfunction, d
- Ursodeoxycholic acid and/or antibiotics for prevention of biliary stent occlusion
Cochrane Systematic Reviews, 10-Nov-2008
Malignant biliary obstruction, which requires endoscopic stenting as palliative therapy, is often complicated by clogging of the stent with subsequent jaundice and/or cholangitis. Stent clogging may be caused by microbiological adhesion and biliary stasis
- Uterine artery embolization for symptomatic uterine fibroids
Cochrane Systematic Reviews, 23-Dec-2014
Uterine fibroids cause heavy prolonged bleeding, pain, pressure symptoms and subfertility. The traditional method of treatment has been surgery as medical therapies have not proven effective. Uterine artery embolization has been reported to be an effectiv
- Vaccines for prophylaxis of viral infections in patients with hematological malignancies
Cochrane Systematic Reviews, 26-Jan-2011
Viral infections cause significant morbidity and mortality in patients with hematological malignancies. It remains uncertain whether viral vaccinations in these patients are supported by good evidence.
- Vaginal dilator therapy for women receiving pelvic radiotherapy
Cochrane Systematic Reviews, 1-Sep-2014
Vaginal dilation therapy is advocated after pelvic radiotherapy to prevent stenosis (abnormal narrowing of the vagina), but can be uncomfortable and psychologically distressing.
- Vascular-endothelial-growth-factor (VEGF) targeting therapies for endocrine refractory or resistant metastatic breast cancer
Cochrane Systematic Reviews, 29-May-2012
Vascular-endothelial-growth-factor (VEGF) is a key mediator of angiogenesis. VEGF-targeting therapies have shown significant benefits and been successfully integrated in routine clinical practice for other types of cancer, such as metastatic colorectal ca
- Voriconazole versus amphotericin B or fluconazole in cancer patients with neutropenia
Cochrane Systematic Reviews, 11-Feb-2015
Opportunistic fungal infections are a major cause of morbidity and mortality in neutropenic cancer patients and antifungal therapy is used both empirically and therapeutically in these patients.
- Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases
Cochrane Systematic Reviews, 24-Feb-2015
Historically, whole brain radiation therapy (WBRT) has been the main treatment for brain metastases. Stereotactic radiosurgery (SRS) delivers high-dose focused radiation and is being increasingly utilized to treat brain metastases. The benefit of adding S
- Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases
Cochrane Systematic Reviews, 8-Mar-2012
Brain metastases represent a significant healthcare problem. It is estimated that 20% to 40% of patients with cancer will develop metastatic cancer to the brain during the course of their illness. The burden of brain metastases impacts on quality and leng
- Workload and surgeon´s specialty for outcome after colorectal cancer surgery
Cochrane Systematic Reviews, 14-Feb-2012
A large body of research has focused on investigating the effects of healthcare provider volume and specialization on patient outcomes including outcomes of colorectal cancer surgery. However there is conflicting evidence about the role of such healthcare
