Showing 3781-3800 of 7110 for: Cochrane Systematic Reviews Back
- Local versus general anaesthesia for carotid endarterectomy
Cochrane Systematic Reviews, 13-Oct-2021
Carotid endarterectomy may significantly reduce the risk of stroke in people with recently symptomatic, severe carotid artery stenosis. However, there are significant perioperative risks that may be minimised by performing the operation under local rather
- Localization techniques for guided surgical excision of non-palpable breast lesions
Cochrane Systematic Reviews, 2-Mar-2016
Breast cancer is the most common form of cancer and the second leading cause of death amongst women in Europe. Amongst five invasive cancers per 1000 women detected in screening, 2.7 were < 15 mm in diameter; and others reported that over one third of exc
- Locomotor training for walking after spinal cord injury
Cochrane Systematic Reviews, 18-Oct-2012
A traumatic spinal cord injury (SCI) is a lesion of neural elements of the spinal cord that can result in any degree of sensory and motor deficit, autonomic or bowel dysfunction. Improvement of locomotor function is one of the primary goals for people wit
- Long term hormone therapy for perimenopausal and postmenopausal women
Cochrane Systematic Reviews, 13-Jun-2012
Hormone therapy (HT) is widely used for controlling menopausal symptoms and has also been used for the management and prevention of cardiovascular disease, osteoporosis and dementia in older women. This is an updated version of a Cochrane review first pub
- Long versus short course treatment with metformin and clomiphene citrate for ovulation induction in women with PCOS
Cochrane Systematic Reviews, 15-Nov-2012
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy among reproductive-aged women. Apart from infertility, women with PCOS often have other endocrine disorders, including insulin resistance, hyperinsulinaemia and hyperandrogenism. Metformin
- Long versus short inspiratory times in neonates receiving mechanical ventilation
Cochrane Systematic Reviews, 11-Nov-2008
When intermittent positive pressure ventilation (IPPV) was introduced in newborn infants with hypoxic respiratory failure from hyaline membrane disease (HMD), mortality was high and air leaks problematic. This barotrauma was caused by the high peak inspir
- Long-acting beta2-agonist in addition to tiotropium versus either tiotropium or long-acting beta2-agonist alone for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 21-Oct-2015
Long-acting bronchodilators, comprising long-acting beta2-agonists (LABA) and long-acting anti-muscarinic agents (LAMA, principally tiotropium), are commonly used for managing persistent symptoms of chronic obstructive pulmonary disease (COPD). Combining
- Long-acting beta2-agonists as an inhaled corticosteroid-sparing agent for chronic asthma in adults and children
Cochrane Systematic Reviews, 29-Mar-2009
The addition of a long acting beta agonist (LABA) to inhaled corticosteroid (ICS) therapy can improve asthma symptoms and reduce exacerbations. The addition of LABA may also have an ICS-sparing effect and permit a reduction in ICS maintenance dose.
- Long-acting beta2-agonists for bronchiectasis
Cochrane Systematic Reviews, 9-Aug-2010
Symptoms of bronchiectasis include chronic productive cough, wheeze, breathlessness and recurrent infections of the lower respiratory tract. Long-acting bronchodilators are being used more frequently in the management of people with this condition.
- Long-acting beta2-agonists for chronic asthma in adults and children where background therapy contains varied or no inhaled corticosteroid
Cochrane Systematic Reviews, 22-Jul-2014
Asthma is a common respiratory disease among both adults and children and short acting inhaled beta-2 agonists are used widely for 'reliever' bronchodilator therapy. Long acting beta-2 agonists (LABA) were introduced as prospective 'symptom controllers' i
- Long-acting beta2-agonists for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 11-Oct-2013
Chronic obstructive pulmonary disease (COPD) is a respiratory disease that causes progressive symptoms of breathlessness, cough and mucus build-up. It is the fourth or fifth most common cause of death worldwide and is associated with significant healthcar
- Long-acting beta2-agonists for poorly reversible chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 21-Nov-2012
Chronic obstructive pulmonary disease (COPD) is characterised by partially reversible airflow limitation. Many patients have little reversibility to short acting bronchodilators, but long acting bronchodilators are frequently advocated.
- Long-acting beta2-agonists versus theophylline for maintenance treatment of asthma
Cochrane Systematic Reviews, 29-Mar-2009
Theophylline and long acting beta-2 agonists are bronchodilators used for the management of persistent asthma symptoms, especially nocturnal asthma. They represent different classes of drug with differing side-effect profiles.
- Long-acting FSH versus daily FSH for women undergoing assisted reproduction
Cochrane Systematic Reviews, 17-Feb-2016
Assisted reproduction techniques (ART), such as in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI), can help subfertile couples to create a family. It is necessary to induce multiple follicles, which is achieved by follicle stimulati
- Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis
Cochrane Systematic Reviews, 24-Mar-2014
Pharmacological therapy for chronic obstructive pulmonary disease (COPD) is aimed at relieving symptoms, improving quality of life and preventing or treating exacerbations.
- Long-acting insulin analogues versus NPH insulin (human isophane insulin) for type 2 diabetes mellitus
Cochrane Systematic Reviews, 16-Aug-2009
Despite indications from epidemiological trials that higher blood glucose concentrations are associated with a higher risk for developing micro- and macrovascular complications, evidence for a beneficial effect of antihyperglycaemic therapy in patients wi
- Long-acting muscarinic antagonists (LAMA) added to combination long-acting beta2-agonists and inhaled corticosteroids (LABA/ICS) versus LABA/ICS for adults with asthma
Cochrane Systematic Reviews, 21-Jan-2016
Maintenance treatment with long-acting beta2-agonists and inhaled corticosteroids (LABA/ICS) can relieve asthma symptoms and reduce the frequency of exacerbations, but there are limited treatment options for people who do not gain control on combination L
- Long‐acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus addition of long‐acting beta2‐agonists (LABA) for adults with asthma
Cochrane Systematic Reviews, 2-Jun-2015
Poorly controlled asthma and preventable exacerbations place a significant strain on healthcare, often requiring additional medications, hospital stays or treatment in the emergency department.
- Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus higher dose ICS for adults with asthma
Cochrane Systematic Reviews, 16-Jul-2015
Long-acting muscarinic antagonists (LAMA), a class of drugs with proven effectiveness in chronic obstructive pulmonary disease (COPD), are being considered as an add-on option for adults with asthma whose condition is uncontrolled on inhaled corticosteroi
- Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus the same dose of ICS alone for adults with asthma
Cochrane Systematic Reviews, 21-Aug-2015
Despite the availability of several evidence-based therapies and non-pharmacological strategies to improve control of symptoms and prevent exacerbations of asthma, patients with asthma continue to be at risk for mortality and morbidity.