- Low‐molecular‐weight heparins or heparinoids versus standard unfractionated heparin for acute ischaemic stroke
Cochrane Systematic Reviews, 4-Apr-2017
Low-molecular-weight heparins (LMWHs) and heparinoids are anticoagulants that may have more powerful antithrombotic effects than standard unfractionated heparin (UFH) but a lower risk of bleeding complications. This is an update of the original Cochrane R - Loxapine for schizophrenia
Cochrane Systematic Reviews, 14-Oct-2015
Some authors have suggested that loxapine is more effective than typical antipsychotics in reducing the negative symptoms of schizophrenia, that extrapyramidal adverse effects are not usually seen at clinically effective antipsychotic doses and that it sh - Lubeluzole for acute ischaemic stroke
Cochrane Systematic Reviews, 30-Aug-2010
Experimental studies have shown that ischaemic insults cause excess release of excitatory amino acid (EAA) neurotransmitters, particularly glutamate. Glutamate re-uptake is impaired under ischaemic conditions. In preclinical models of stroke, antagonists - Lumbar supports for prevention and treatment of low back pain
Cochrane Systematic Reviews, 18-Jan-2011
Lumbar supports are used in the treatment of low-back pain patients, to prevent the onset of low-back pain (primary prevention) or to prevent recurrences of a low-back pain episode (secondary prevention). - Lung lavage for meconium aspiration syndrome in newborn infants
Cochrane Systematic Reviews, 29-Mar-2013
Meconium aspiration syndrome (MAS) can occur when a newborn infant inhales a mixture of meconium and amniotic fluid into the lungs around the time of delivery. Other than supportive measures, little effective therapy is available. Lung lavage may be a pot - Lung protective ventilation strategy for the acute respiratory distress syndrome
Cochrane Systematic Reviews, 14-Jan-2013
Patients with acute respiratory distress syndrome and acute lung injury require mechanical ventilatory support. Acute respiratory distress syndrome and acute lung injury are further complicated by ventilator-induced lung injury. Lung protective ventilatio - Lung volume reduction surgery for diffuse emphysema
Cochrane Systematic Reviews, 12-Oct-2008
Lung volume reduction surgery (LVRS) has been re-introduced for treating patients with severe diffuse emphysema. It is a procedure that aims to improve long-term daily functioning, although it is costly and may also be associated with a high risk of morta - Luteal phase support for assisted reproduction cycles
Cochrane Systematic Reviews, 6-Nov-2015
Progesterone prepares the endometrium for pregnancy by stimulating proliferation in response to human chorionic gonadotropin (hCG) produced by the corpus luteum in the luteal phase of the menstrual cycle. In assisted reproduction techniques (ART), progest - Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse
Cochrane Systematic Reviews, 24-Aug-2022
Ovulation induction may impact endometrial receptivity due to insufficient progesterone secretion. Low progesterone is associated with poor pregnancy outcomes. - Luteal phase support in assisted reproduction cycles
Cochrane Systematic Reviews, 17-Jul-2008
The aspiration of the granulosa cells that surround the oocyte and the use of gonadotropin releasing hormone agonists (GnRHa) during assisted reproduction technology (ART) treatment can interfere with the production, during the luteal phase, of progestero - Lycopene for the prevention of prostate cancer
Cochrane Systematic Reviews, 25-Oct-2011
Prostate cancer is a common cause of death in developed countries, yet the benefits of screening for prostate cancer still remain controversial. A prostate-specific antigen (PSA) test result greater than 4 ng/mL (nanograms/millilitre) has commonly been us - Lymphadenectomy for the management of endometrial cancer
Cochrane Systematic Reviews, 15-Sep-2015
This is an update of a previous Cochrane review published in Issue 1, 2010. The role of lymphadenectomy in surgical management of endometrial cancer remains controversial. Lymph node metastases can be found in approximately 10% of women who clinically bef - Macrolide antibiotics for cystic fibrosis
Cochrane Systematic Reviews, 12-Sep-2012
Macrolide antibiotics may have a modifying role in diseases which involve airway infection and inflammation, like cystic fibrosis. - Macrolides for diffuse panbronchiolitis
Cochrane Systematic Reviews, 22-Jan-2015
Diffuse panbronchiolitis (DPB) is a chronic airways disease predominantly affecting East Asians. Macrolides, a class of antibiotics, have been used as the main treatment for DPB, based on evidence from retrospective and non-randomised studies. - Macrolides versus placebo for chronic asthma
Cochrane Systematic Reviews, 22-Nov-2021
Asthma is a chronic disease in which inflammation of the airways causes symptomatic wheezing, coughing and difficult breathing. Macrolides are antibiotics with antimicrobial and anti-inflammatory activities that have been explored for the long-term contro - Macular grid laser photocoagulation for branch retinal vein occlusion
Cochrane Systematic Reviews, 11-May-2015
Branch retinal vein occlusion (BRVO) is the second most common cause of retinal vascular abnormality after diabetic retinopathy. Persistent macular oedema develops in 60% of eyes with a BRVO. Untreated, only 14% of eyes with chronic macular oedema will ha - Macular translocation for neovascular age-related macular degeneration
Cochrane Systematic Reviews, 6-Apr-2009
Macular translocation has been proposed by vitreoretinal surgeons to displace the neuroretinal tissue onto healthy retinal pigment epithelium and choroid when the macula has been invaded by subretinal neovascularisation. - Magnesium for acute traumatic brain injury
Cochrane Systematic Reviews, 14-Aug-2008
Acute traumatic brain injury is a leading cause of death and disability in young adults. Numerous pharmacological and non-pharmacological tools have been investigated and considered as potential mechanisms for improving neurological outcome. Magnesium has - Magnesium for alcohol withdrawal
Cochrane Systematic Reviews, 28-May-2013
Patients have been given magnesium to treat or prevent alcohol withdrawal syndrome (AWS). Evidence to support this practice is limited, and is often based on the controversial link between hypomagnesaemia and AWS. - Magnesium for skeletal muscle cramps
Cochrane Systematic Reviews, 21-Sep-2020
Skeletal muscle cramps are common and often occur in association with pregnancy, advanced age, exercise or motor neuron disorders (such as amyotrophic lateral sclerosis). Typically, such cramps have no obvious underlying pathology, and so are termed idiop
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