Showing 21-40 of 374 for: Cochrane Systematic Reviews > Oncology 
- Amphotericin B versus fluconazole for controlling fungal infections in neutropenic cancer patients
Cochrane Systematic Reviews, 3-Sep-2014
Systemic fungal infection is considered to be an important cause of morbidity and mortality in cancer patients, particularly those with neutropenia. Antifungal drugs are often given prophylactically, or empirically to patients with persistent fever.
- Angiogenesis inhibitors for the treatment of ovarian cancer
Cochrane Systematic Reviews, 20-Jul-2011
Many women with ovarian cancer eventually develop resistance to conventional chemotherapy drugs, and so novel agents are being developed to target specific molecular pathways. One such class of drugs inhibits angiogenesis (the development of new blood ves
- Angiogenesis-inhibitors for metastatic thyroid cancer
Cochrane Systematic Reviews, 16-Feb-2010
Systemic cytostatic therapies for advanced, metastatic thyroid carcinomas have been poorly effective. Tumor growth and metastasis depend on blood supply and blood vessel formation (angiogenesis). Therefore, inhibition of angiogenesis may represent a promi
- Anti-angiogenic therapies for metastatic colorectal cancer
Cochrane Systematic Reviews, 12-May-2009
Angiogenesis inhibitors have been developed to block tumour angiogenesis and target vascular endothelial cells. While some of them have already been approved by the health authorities and are successfully integrated into patient care, many others are stil
- Antibiotic prophylaxis for bacterial infections in afebrile neutropenic patients following chemotherapy
Cochrane Systematic Reviews, 24-Feb-2015
Bacterial infections are a major cause of morbidity and mortality in patients who are neutropenic following chemotherapy for malignancy. Trials have shown the efficacy of antibiotic prophylaxis in reducing the incidence of bacterial infections but not in
- Anticoagulation for the initial treatment of venous thromboembolism in patients with cancer
Cochrane Systematic Reviews, 11-Feb-2015
Compared with patients without cancer, patients with cancer who receive anticoagulant treatment for venous thromboembolism (VTE) are more likely to develop recurrent VTE.
- Anticoagulation for the long‐term treatment of venous thromboembolism in people with cancer
Cochrane Systematic Reviews, 19-Jun-2018
Cancer increases the risk of thromboembolic events, especially in people receiving anticoagulation treatments.
- Antiemetic medication for prevention and treatment of chemotherapy-induced nausea and vomiting in childhood
Cochrane Systematic Reviews, 22-Dec-2015
Nausea and vomiting remain a problem for children undergoing treatment for malignancies despite new antiemetic therapies. Optimising antiemetic regimens could improve quality of life by reducing nausea, vomiting, and associated clinical problems. This is
- Antiepileptic drugs for preventing seizures in people with brain tumors
Cochrane Systematic Reviews, 19-Oct-2008
Seizures can present at any time before or after diagnosis of a brain tumor. The risk of seizures varies by tumor type and its location in the brain. For a long time we believed that preventing seizures with antiepileptic drugs (seizure prophylaxis) was e
- Antiepileptic drugs for treating seizures in adults with brain tumours
Cochrane Systematic Reviews, 4-Jul-2011
Seizures are a common symptom of brain tumours. The mainstay of treatment for seizures is medical therapy with antiepileptic drugs.
- Antigen-specific active immunotherapy for ovarian cancer
Cochrane Systematic Reviews, 10-Sep-2014
Despite advances in chemotherapy, prognosis of ovarian cancer remains poor. Antigen-specific active immunotherapy aims to induce tumour-antigen-specific anti-tumour immune responses as an alternative treatment for ovarian cancer.
- Antioxidant supplements for preventing gastrointestinal cancers
Cochrane Systematic Reviews, 25-May-2008
Oxidative stress may cause gastrointestinal cancers. The evidence on whether antioxidant supplements are effective in preventing gastrointestinal cancers is contradictory.
- Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases
Cochrane Systematic Reviews, 14-Mar-2012
Our systematic review has demonstrated that antioxidant supplements may increase mortality. We have now updated this review.
- Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia
Cochrane Systematic Reviews, 15-Mar-2013
Polycythaemia vera and essential thrombocythaemia are chronic Philadelphia-negative myeloproliferative neoplasms that increase the risk of arterial and venous thrombosis, as well as bleeding. In addition to the different therapeutic strategies available,
- Antitumour antibiotic containing regimens for metastatic breast cancer
Cochrane Systematic Reviews, 6-Aug-2008
Antitumour antibiotics are used in the management of metastatic breast cancer. Some of these agents have demonstrated higher tumour response rates than non-antitumour antibiotic regimens, however a survival benefit has not been established in this setting
- Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women
Cochrane Systematic Reviews, 5-Aug-2009
Endocrine therapy removes the influence of oestrogen on breast cancer cells and so hormonal treatments such as tamoxifen, megestrol acetate and medroxyprogesterone acetate have been in use for many years for advanced breast cancer. Aromatase inhibitors (A
- Aromatherapy and massage for symptom relief in patients with cancer
Cochrane Systematic Reviews, 11-Jun-2013
Aromatherapy massage is a commonly used complementary therapy, and is employed in cancer and palliative care largely to improve quality of life and reduce psychological distress.
- Autologous hematopoietic stem cell transplantation following high dose chemotherapy for non-rhabdomyosarcoma soft tissue sarcomas
Cochrane Systematic Reviews, 1-Apr-2015
Soft tissue sarcomas (STS) are a highly heterogeneous group of rare malignant solid tumors. Non-rhabdomyosarcoma soft tissue sarcomas (NRSTS) comprise all STS except rhabdomyosarcoma. In patients with advanced local or metastatic disease, autologous hemat
- Azathioprine for primary biliary cirrhosis
Cochrane Systematic Reviews, 15-Oct-2008
Azathioprine is used for patients with primary biliary cirrhosis, but the therapeutic responses in randomised clinical trials have been conflicting.
- Beta-lactam versus beta-lactam-aminoglycoside combination therapy in cancer patients with neutropenia
Cochrane Systematic Reviews, 11-Feb-2015
Continued controversy surrounds the optimal empirical treatment for febrile neutropenia. New broad-spectrum beta-lactams have been introduced as single treatment, and classically, a combination of a beta-lactam with an aminoglycoside has been used.
