Showing 381-400 of 723 for: Cochrane Systematic Reviews > Musculoskeletal 
- Intra-articular corticosteroid for knee osteoarthritis
Cochrane Systematic Reviews, 22-Oct-2015
Knee osteoarthritis is a leading cause of chronic pain, disability, and decreased quality of life. Despite the long-standing use of intra-articular corticosteroids, there is an ongoing debate about their benefits and safety. This is an update of a Cochran
- Intra-articular lignocaine versus intravenous analgesia with or without sedation for manual reduction of acute anterior shoulder dislocation in adults
Cochrane Systematic Reviews, 4-Jan-2013
There is conflicting evidence regarding the use of intra-articular lignocaine injection for the closed manual reduction of acute anterior shoulder dislocations. A systematic review may help cohere the conflicting evidence.
- Intra‐articular steroids and splints/rest for children with juvenile idiopathic arthritis and adults with rheumatoid arthritis
Cochrane Systematic Reviews, 25-Jan-2006
Resting or immobilizing a joint to enhance outcomes following intra-articular (IA) steroid injection is generally advocated. This systematic review aimed to determine the efficacy of IA steroid injections and the influence of post-injection rest.
- Intramedullary nailing for tibial shaft fractures in adults
Cochrane Systematic Reviews, 7-Dec-2011
Intramedullary nailing is commonly used for treating fractures of the tibial shaft. These fractures are one of the most common long bone fractures in adults.
- Intramedullary nails for extracapsular hip fractures in adults
Cochrane Systematic Reviews, 9-Sep-2014
Intramedullary nails may be used for the surgical fixation of extracapsular hip fractures in adults. This is an update of a Cochrane review first published in 2005 and last updated in 2008.
- Intranasal corticosteroids for asthma control in people with coexisting asthma and rhinitis
Cochrane Systematic Reviews, 21-Jul-2003
Allergic rhinitis and asthma are mediated by similar allergic mechanisms. They may represent two manifestations of the same united airway disease and therefore intranasal corticosteroids (INCS) could improve asthma. Nevertheless none of the asthma guideli
- Intranasal steroids for acute sinusitis
Cochrane Systematic Reviews, 2-Dec-2013
Acute sinusitis is a common reason for primary care visits. It causes significant symptoms and often results in time off work and school.
- Intravenous dexamethasone for extubation of newborn infants
Cochrane Systematic Reviews, 23-Oct-2001
Endotracheal tubes are foreign bodies that may injure the upper airway causing laryngeal edema. This in turn may result in failure of extubation in preterm infants. Corticosteroids have been used prophylactically to reduce upper airway obstruction and fac
- Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy
Cochrane Systematic Reviews, 20-Dec-2013
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) causes progressive or relapsing weakness and numbness of the limbs, developing over at least two months. Uncontrolled studies suggest that intravenous immunoglobulin (IVIg) helps. This revie
- Intravenous immunoglobulin for myasthenia gravis
Cochrane Systematic Reviews, 12-Dec-2012
Myasthenia gravis is an autoimmune disease in which autoantibodies interfere with neuromuscular transmission. As with other autoimmune diseases, people with myasthenia gravis would be expected to benefit from intravenous immunoglobulin (IVIg). This is an
- Intravenous immunoglobulin for the treatment of Kawasaki disease in children
Cochrane Systematic Reviews, 20-Oct-2003
Kawasaki disease is the most common cause of acquired heart disease in children in developed countries. The coronary arteries supplying the heart can be damaged in Kawasaki disease. The principal advantage of timely diagnosis is the potential to prevent t
- Intravenous lidocaine for the treatment of background or procedural burn pain
Cochrane Systematic Reviews, 16-Oct-2014
This is an update of the review on "Lidocaine for pain relief in burn injured patients" first published in Issue 3, 2007, and first updated in 2012. Pain is a major issue for people with many different types of wounds, in particular those people with burn
- Intravitreal steroids for macular edema in diabetes
Cochrane Systematic Reviews, 17-Nov-2020
Diabetic macular edema (DME) is secondary to leakage from diseased retinal capillaries with thickening of central retina, and is an important cause of poor central visual acuity in people with diabetic retinopathy. Intravitreal steroids have been used to
- Iron for the treatment of restless legs syndrome
Cochrane Systematic Reviews, 4-Jan-2019
Restless legs syndrome (RLS) is a common neurologic disorder that is associated with peripheral iron deficiency in a subgroup of patients. It is unclear whether iron therapy is effective treatment for RLS.
- Joint lavage for osteoarthritis of the knee
Cochrane Systematic Reviews, 13-Apr-2010
Osteoarthritis is the most common form of joint disorder and a leading cause of pain and physical disability. Observational studies suggested a benefit for joint lavage, but recent, sham-controlled trials yielded conflicting results, suggesting joint lava
- Ketanserin for Raynaud's phenomenon in progressive systemic sclerosis
Cochrane Systematic Reviews, 27-Apr-1998
Scleroderma is a connective tissue disease causing fibrosis and commonly affects the skin and internal organs such as the GI tract, lungs, kidney and heart. Most people with scleroderma also have Raynaud's phenomenon (RP). One of the possible treatment op
- Lacosamide for neuropathic pain and fibromyalgia in adults
Cochrane Systematic Reviews, 15-Feb-2012
Antiepileptic drugs have been used in pain management since the 1960s; some seem to be especially useful for neuropathic pain. Lacosamide is an antiepileptic drug that has recently been investigated for neuropathic pain relief, although it failed to get a
- Laparoscopic versus open surgical techniques for ventral or incisional hernia repair
Cochrane Systematic Reviews, 10-Feb-2011
There are many different techniques currently in use for ventral and incisional hernia repair. Laparoscopic techniques have become more common in recent years, although the evidence is sparse.
- Late (≥ 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants
Cochrane Systematic Reviews, 11-Nov-2021
Many infants born preterm develop bronchopulmonary dysplasia (BPD), with lung inflammation playing a role. Corticosteroids have powerful anti-inflammatory effects and have been used to treat individuals with established BPD. However, it is unclear whether
- Leflunomide for the treatment of rheumatoid arthritis
Cochrane Systematic Reviews, 22-Jul-2002
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease. Leflunomide is one of the more recent oral agents, classified as a disease-modifying antirheumatic drug (DMARD). It has a different mechanism of action than other existing DMARDs.
