Showing 401-420 of 753 for: Cochrane Systematic Reviews > Pharmacotherapeutics 
- Interventions to improve safe and effective medicines use by consumers: an overview of systematic reviews
Cochrane Systematic Reviews, 29-Apr-2014
Many systematic reviews exist on interventions to improve safe and effective medicines use by consumers, but research is distributed across diseases, populations and settings. The scope and focus of such reviews also vary widely, creating challenges for d
- Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use
Cochrane Systematic Reviews, 26-Aug-2022
Heavy menstrual bleeding and pain are common reasons women discontinue intrauterine device (IUD) use. Copper IUD (Cu IUD) users tend to experience increased menstrual bleeding, whereas levonorgestrel IUD (LNG IUD) users tend to have irregular menstruation
- Intra-articular corticosteroid for knee osteoarthritis
Cochrane Systematic Reviews, 22-Oct-2015
Knee osteoarthritis is a leading cause of chronic pain, disability, and decreased quality of life. Despite the long-standing use of intra-articular corticosteroids, there is an ongoing debate about their benefits and safety. This is an update of a Cochran
- Intra-articular steroids and splints/rest for children with juvenile idiopathic arthritis and adults with rheumatoid arthritis
Cochrane Systematic Reviews, 2-Jul-2008
Resting or immobilizing a joint to enhance outcomes following intra-articular (IA) steroid injection is generally advocated. This systematic review aimed to determine the efficacy of IA steroid injections and the influence of post-injection rest.
- Intranasal corticosteroids for asthma control in people with coexisting asthma and rhinitis
Cochrane Systematic Reviews, 29-Mar-2009
Allergic rhinitis and asthma are mediated by similar allergic mechanisms. They may represent two manifestations of the same united airway disease and therefore intranasal corticosteroids (INCS) could improve asthma. Nevertheless none of the asthma guideli
- Intranasal steroids for acute sinusitis
Cochrane Systematic Reviews, 2-Dec-2013
Acute sinusitis is a common reason for primary care visits. It causes significant symptoms and often results in time off work and school.
- Intra-pleural fibrinolytic therapy versus conservative management in the treatment of adult parapneumonic effusions and empyema
Cochrane Systematic Reviews, 31-Mar-2009
Pleural effusions and empyema may complicate lower respiratory tract infections. Treatment of these collections of pus includes surgical drainage and the use of intra-pleural fibrinolysis to break down fibrin bands that may cause loculation.
- Intravenous dexamethasone for extubation of newborn infants
Cochrane Systematic Reviews, 1-Nov-2008
Endotracheal tubes are foreign bodies that may injure the upper airway causing laryngeal edema. This in turn may result in failure of extubation in preterm infants. Corticosteroids have been used prophylactically to reduce upper airway obstruction and fac
- Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy
Cochrane Systematic Reviews, 20-Dec-2013
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) causes progressive or relapsing weakness and numbness of the limbs, developing over at least two months. Uncontrolled studies suggest that intravenous immunoglobulin (IVIg) helps. This revie
- Intravenous immunoglobulin for Guillain-Barré syndrome
Cochrane Systematic Reviews, 19-Sep-2014
Guillain-Barré syndrome (GBS) is an acute, paralysing, inflammatory peripheral nerve disease. Intravenous immunoglobulin (IVIg) is beneficial in other autoimmune diseases. This is an update of a review first published in 2001 and previously updated in 200
- Intravenous immunoglobulin for multifocal motor neuropathy
Cochrane Systematic Reviews, 3-Nov-2008
Multifocal motor neuropathy is a rare, probably immune mediated disorder characterised by slowly progressive, asymmetric, distal weakness of one or more limbs with no objective loss of sensation. It may cause prolonged periods of disability. The treatment
- Intravenous immunoglobulin for myasthenia gravis
Cochrane Systematic Reviews, 14-Nov-2012
Myasthenia gravis is an autoimmune disease in which autoantibodies interfere with neuromuscular transmission. As with other autoimmune diseases, people with myasthenia gravis would be expected to benefit from intravenous immunoglobulin (IVIg). This is an
- Intravenous immunoglobulin for presumed viral myocarditis in children and adults
Cochrane Systematic Reviews, 5-May-2015
This is an update of a previous review. Case reports and case series have described dramatic responses to intravenous immunoglobulin (IVIG) in people with presumed viral myocarditis, and its administration has become commonplace.
- Intravenous immunoglobulin for preventing infection in preterm and/or low birth weight infants
Cochrane Systematic Reviews, 2-Jul-2013
Nosocomial infections continue to be a significant cause of morbidity and mortality among preterm and/or low birth weight (LBW) infants. Preterm infants are deficient in immunoglobulin G (IgG); therefore, administration of intravenous immunoglobulin (IVIG
- Intravenous immunoglobulin for suspected or proven infection in neonates
Cochrane Systematic Reviews, 27-Mar-2015
Neonates are at higher risk of infection due to immuno-incompetence. Maternal transport of immunoglobulins to the fetus mainly occurs after 32 weeks' gestation, and endogenous synthesis begins several months after birth. Administration of intravenous immu
- Intravenous immunoglobulin for the treatment of Kawasaki disease in children
Cochrane Systematic Reviews, 25-Aug-2008
Kawasaki disease is the most common cause of acquired heart disease in children in developed countries. The coronary arteries supplying the heart can be damaged in Kawasaki disease. The principal advantage of timely diagnosis is the potential to prevent t
- Intravenous immunoglobulin for treating sepsis, severe sepsis and septic shock
Cochrane Systematic Reviews, 13-Sep-2013
Mortality from sepsis and septic shock remains high. Results of trials on intravenous immunoglobulins (IVIG) as adjunctive therapy for sepsis have been conflicting. This is an update of a Cochrane review that was originally published in 1999 and updated i
- Intravenous immunoglobulins for multiple sclerosis
Cochrane Systematic Reviews, 19-Jan-2010
Animal experiments suggest that intravenous immunoglobulins can reverse some of the disease process of central nervous system demyelination. Subsequently, clinical trials of intravenous immunoglobulins have been conducted in people with multiple sclerosis
- Intravenous lidocaine for the treatment of background or procedural burn pain
Cochrane Systematic Reviews, 17-Oct-2014
This is an update of the review on "Lidocaine for pain relief in burn injured patients" first published in Issue 3, 2007, and first updated in 2012. Pain is a major issue for people with many different types of wounds, in particular those people with burn
- Intravenous or enteral loop diuretics for preterm infants with (or developing) chronic lung disease
Cochrane Systematic Reviews, 7-Aug-2011
Lung disease in preterm infants is often complicated with lung edema.
