- Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis
Cochrane Systematic Reviews, 4-Jan-2021
Multiple studies have identified the prognostic relevance of extent of resection in the management of glioma. Different intraoperative technologies have emerged in recent years with unknown comparative efficacy in optimising extent of resection. One previ - Intraoperative interventions for preventing surgical site infection: an overview of Cochrane Reviews
Cochrane Systematic Reviews, 6-Feb-2018
Surgical site infection (SSI) rates vary from 1% to 5% in the month following surgery. Due to the large number of surgical procedures conducted annually, the costs of these SSIs can be considerable in financial and social terms. Many interventions are use - Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental treatment in children and adolescents
Cochrane Systematic Reviews, 23-Dec-2014
Whilst carrying out dental procedures under general anaesthesia (GA), practitioners routinely give local anaesthetics (LA) intraoperatively to children. Local anaesthetics are used to help manage postoperative pain and reduce bleeding and the physiologica - Intraoperative mild hypothermia for postoperative neurological deficits in people with intracranial aneurysm
Cochrane Systematic Reviews, 22-Mar-2016
Rupture of an intracranial aneurysm causes aneurysmal subarachnoid haemorrhage, which is one of the most devastating clinical conditions. It can be classified into five Grades using the Hunt-Hess or World Federation of Neurological Surgeons (WFNS) scale. - Intraoperative Mitomycin C for glaucoma surgery
Cochrane Systematic Reviews, 19-Oct-2005
Trabeculectomy is performed as a treatment for glaucoma to lower the intraocular pressure (IOP). Mitomycin C (MMC) is an antimetabolite used during the initial stages of a trabeculectomy to prevent excessive postoperative scarring and thus reduce the risk - Intraoperative neuromonitoring versus visual nerve identification for prevention of recurrent laryngeal nerve injury in adults undergoing thyroid surgery
Cochrane Systematic Reviews, 19-Jan-2019
Injuries to the recurrent inferior laryngeal nerve (RILN) remain one of the major post-operative complications after thyroid and parathyroid surgery. Damage to this nerve can result in a temporary or permanent palsy, which is associated with vocal cord pa - Intraoperative use of low volume ventilation to decrease postoperative mortality, mechanical ventilation, lengths of stay and lung injury in adults without acute lung injury
Cochrane Systematic Reviews, 9-Jul-2018
Since the 2000s, there has been a trend towards decreasing tidal volumes for positive pressure ventilation during surgery. This an update of a review first published in 2015, trying to determine if lower tidal volumes are beneficial or harmful for patient - Intrapartum antibiotics for known maternal Group B streptococcal colonization
Cochrane Systematic Reviews, 10-Jun-2014
Maternal colonization with group B streptococcus (GBS) during pregnancy increases the risk of neonatal infection by vertical transmission. Administration of intrapartum antibiotic prophylaxis (IAP) during labor has been associated with a reduction in earl - Intrapartum fetal scalp lactate sampling for fetal assessment in the presence of a non‐reassuring fetal heart rate trace
Cochrane Systematic Reviews, 1-May-2015
Fetal scalp blood sampling for lactate estimation may be considered following identification of an abnormal or non-reassuring fetal heart rate pattern. The smaller volume of blood required for this test, compared with the more traditional pH estimation, m - Intrapartum interventions for preventing shoulder dystocia
Cochrane Systematic Reviews, 18-Oct-2006
The early management of shoulder dystocia involves the administration of various manoeuvres which aim to relieve the dystocia by manipulating the fetal shoulders and increasing the functional size of the maternal pelvis. - Intraperitoneal chemotherapy for the initial management of primary epithelial ovarian cancer
Cochrane Systematic Reviews, 12-Jan-2016
Ovarian cancer tends to be chemosensitive and confine itself to the surface of the peritoneal cavity for much of its natural history. These features have made it an obvious target for intraperitoneal (IP) chemotherapy. Chemotherapy for ovarian cancer is u - Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for laparoscopic cholecystectomy
Cochrane Systematic Reviews, 25-Oct-2021
Pain is one of the important reasons for delayed discharge after laparoscopic cholecystectomy. Use of intraperitoneal local anaesthetic for laparoscopic cholecystectomy may be a way of reducing pain. A previous version of this Cochrane Review found very l - Intra‐peritoneal prophylactic agents for preventing adhesions and adhesive intestinal obstruction after non‐gynaecological abdominal surgery
Cochrane Systematic Reviews, 21-Jan-2009
Intra-abdominal adhesions are common and challenge patients, surgeons and other healthcare providers. They are potentially preventable and several agents that act as barriers between adjacent peritoneal surfaces have been evaluated for prophylaxis. Effica - Intra‐pleural fibrinolytic therapy versus placebo, or a different fibrinolytic agent, in the treatment of adult parapneumonic effusions and empyema
Cochrane Systematic Reviews, 30-Oct-2019
Pleural infection, including parapneumonic effusions and thoracic empyema, may complicate lower respiratory tract infections. Standard treatment of these collections in adults involves antibiotic therapy, effective drainage of infected fluid and surgical - Intrarectal quinine versus intravenous or intramuscular quinine for treating Plasmodium falciparum malaria
Cochrane Systematic Reviews, 21-Jan-2009
In children with falciparum malaria, a proprietary quinine preparation (adjusted to make it less acidic) administered rectally may be easier to use and less painful than intramuscular or intravenous administration. However, rectal quinine may be less effe - Intrastromal corneal ring segments for treating keratoconus
Cochrane Systematic Reviews, 9-May-2019
Keratoconus is a degenerative condition of the cornea that profoundly affects vision and vision-specific quality of life. The axial cornea thins and protrudes, resulting in irregularity and, eventually, scarring of the cornea. There are multiple options a - Intrathecal baclofen for treating spasticity in children with cerebral palsy
Cochrane Systematic Reviews, 12-Nov-2015
Cerebral palsy is a disorder of movement and posture arising from a non-progressive lesion in the developing brain. Spasticity, a disorder of increased muscle tone, is the most common motor difficulty and is associated with activity limitation to varying - Intratracheal Clara cell secretory protein (CCSP) administration in preterm infants with or at risk of respiratory distress syndrome
Cochrane Systematic Reviews, 11-May-2011
Clara cell secretory protein (CCSP) is an immune-modulating and anti-inflammatory agent. CCSP is available synthetically as recombinant human Clara cell protein (rhCC10). It has been shown in animal models to reduce lung injury, improve pulmonary complian - Intratympanic corticosteroids for Ménière’s disease
Cochrane Systematic Reviews, 27-Feb-2023
Ménière's disease is a condition that causes recurrent episodes of vertigo, associated with hearing loss and tinnitus. Corticosteroids are sometimes administered directly into the middle ear to treat this condition (through the tympanic membrane). The und - Intratympanic corticosteroids for sudden sensorineural hearing loss
Cochrane Systematic Reviews, 22-Jul-2022
Idiopathic sudden sensorineural hearing loss (ISSNHL) is common, and defined as a sudden decrease in sensorineural hearing sensitivity of unknown aetiology. Systemic corticosteroids are widely used, however their value remains unclear. Intratympanic injec
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