- Intravenous immunoglobulin for Guillain‐Barré syndrome
Cochrane Systematic Reviews, 19-Sep-2014
Guillain-Barré syndrome (GBS) is an acute, paralysing, inflammatory peripheral nerve disease. Intravenous immunoglobulin (IVIg) is beneficial in other autoimmune diseases. This is an update of a review first published in 2001 and previously updated in 200 - Intravenous immunoglobulin for myasthenia gravis
Cochrane Systematic Reviews, 12-Dec-2012
Myasthenia gravis is an autoimmune disease in which autoantibodies interfere with neuromuscular transmission. As with other autoimmune diseases, people with myasthenia gravis would be expected to benefit from intravenous immunoglobulin (IVIg). This is an - Intravenous immunoglobulin for presumed viral myocarditis in children and adults
Cochrane Systematic Reviews, 19-Aug-2020
This is an update of a previous review. Case reports and case series have described dramatic responses to intravenous immunoglobulin (IVIG) in people with presumed viral myocarditis, and its administration has become commonplace. - Intravenous immunoglobulin for preventing infection in preterm and/or low birth weight infants
Cochrane Systematic Reviews, 29-Jan-2020
Nosocomial infections continue to be a significant cause of morbidity and mortality among preterm and/or low birth weight (LBW) infants. Preterm infants are deficient in immunoglobulin G (IgG); therefore, administration of intravenous immunoglobulin (IVIG - Intravenous immunoglobulin for suspected or proven infection in neonates
Cochrane Systematic Reviews, 29-Jan-2020
Neonates are at higher risk of infection due to immuno-incompetence. Maternal transport of immunoglobulins to the fetus mainly occurs after 32 weeks' gestation, and endogenous synthesis begins several months after birth. Administration of intravenous immu - Intravenous immunoglobulin for the treatment of childhood encephalitis
Cochrane Systematic Reviews, 28-Sep-2017
Encephalitis is a syndrome of neurological dysfunction due to inflammation of the brain parenchyma, caused by an infection or an exaggerated host immune response, or both. Attenuation of brain inflammation through modulation of the immune response could i - Intravenous immunoglobulin for the treatment of Kawasaki disease
Cochrane Systematic Reviews, 25-Jan-2023
Kawasaki disease (KD) is an acute systemic vasculitis (inflammation of the blood vessels) that mainly affects children. Symptoms include fever, chapped lips, strawberry tongue, red eyes (bulbar conjunctival injection), rash, redness, swollen hands and fee - Intravenous immunoglobulin for the treatment of Kawasaki disease in children
Cochrane Systematic Reviews, 20-Oct-2003
Kawasaki disease is the most common cause of acquired heart disease in children in developed countries. The coronary arteries supplying the heart can be damaged in Kawasaki disease. The principal advantage of timely diagnosis is the potential to prevent t - Intravenous immunoglobulin for treating sepsis, severe sepsis and septic shock
Cochrane Systematic Reviews, 16-Sep-2013
Mortality from sepsis and septic shock remains high. Results of trials on intravenous immunoglobulins (IVIG) as adjunctive therapy for sepsis have been conflicting. This is an update of a Cochrane review that was originally published in 1999 and updated i - Intravenous immunoglobulins for epilepsy
Cochrane Systematic Reviews, 2-Dec-2019
Epilepsy is a common neurological condition, with an estimated incidence of 50 per 100,000 persons. People with epilepsy may present with various types of immunological abnormalities, such as low serum immunoglobulin A (IgA) levels, lack of the immunoglob - Intravenous immunoglobulins for multiple sclerosis
Cochrane Systematic Reviews, 21-Jul-2003
Animal experiments suggest that intravenous immunoglobulins can reverse some of the disease process of central nervous system demyelination. Subsequently, clinical trials of intravenous immunoglobulins have been conducted in people with multiple sclerosis - Intravenous in‐line filters for preventing morbidity and mortality in neonates
Cochrane Systematic Reviews, 6-Aug-2015
Venous access is an essential part of caring for the sick neonate. However, problems such as contamination of fluids with bacteria, endotoxins and particulates have been associated with intravenous infusion therapy. Intravenous in-line filters claim to be - Intravenous iron therapy for non‐anaemic, iron‐deficient adults
Cochrane Systematic Reviews, 20-Dec-2019
Iron deficiency is one of the most common nutritional deficiencies, and has a number of physiological manifestations. Early, or non-anaemic iron deficiency can result in fatigue and diminished exercise capacity. Oral iron preparations have a high incidenc - Intravenous iron versus oral iron versus no iron with or without erythropoiesis‐ stimulating agents (ESA) for cancer patients with anaemia: a systematic review and network meta‐analysis
Cochrane Systematic Reviews, 20-Jun-2022
Anaemia is common among cancer patients and they may require red blood cell transfusions. Erythropoiesis-stimulating agents (ESAs) and iron might help in reducing the need for red blood cell transfusions. However, it remains unclear whether the combinatio - Intravenous lidocaine for the treatment of background or procedural burn pain
Cochrane Systematic Reviews, 16-Oct-2014
This is an update of the review on "Lidocaine for pain relief in burn injured patients" first published in Issue 3, 2007, and first updated in 2012. Pain is a major issue for people with many different types of wounds, in particular those people with burn - Intravenous magnesium for acute myocardial infarction
Cochrane Systematic Reviews, 18-Apr-2007
Mortality and morbidity from acute myocardial infarction (AMI) remain high. Intravenous magnesium started early after the onset of AMI is thought to be a promising adjuvant treatment. Conflicting results from earlier trials and meta-analyses warrant a sys - Intravenous magnesium sulfate for treating adults with acute asthma in the emergency department
Cochrane Systematic Reviews, 21-May-2014
Asthma is a chronic respiratory condition characterised by airways inflammation, constriction of airway smooth muscle and structural alteration of the airways that is at least partially reversible. Exacerbations of asthma can be life threatening and place - Intravenous magnesium sulfate for treating children with acute asthma in the emergency department
Cochrane Systematic Reviews, 28-Apr-2016
Acute asthma in children can be life-threatening and must be treated promptly in the emergency setting. Intravenous magnesium sulfate is recommended by various guidelines for cases of acute asthma that have not responded to first-line treatment with bronc - Intravenous midazolam infusion for sedation of infants in the neonatal intensive care unit
Cochrane Systematic Reviews, 31-Jan-2017
Proper sedation for neonates undergoing uncomfortable procedures may reduce stress and avoid complications. Midazolam is a short-acting benzodiazepine that is used increasingly in neonatal intensive care units (NICUs). However, its effectiveness as a seda - Intravenous naftidrofuryl for critical limb ischaemia
Cochrane Systematic Reviews, 11-Jul-2012
Peripheral arterial disease affects five per cent of men and women by late middle age. Approximately 25% of those affected will develop critical limb ischaemia (rest pain, ulceration and gangrene) within five years. Naftidrofuryl is a vasoactive drug whic
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