Showing 441-460 of 753 for: Cochrane Systematic Reviews > Pharmacotherapeutics 
- Long-acting beta2-agonists versus theophylline for maintenance treatment of asthma
Cochrane Systematic Reviews, 29-Mar-2009
Theophylline and long acting beta-2 agonists are bronchodilators used for the management of persistent asthma symptoms, especially nocturnal asthma. They represent different classes of drug with differing side-effect profiles.
- Long-term antibiotics for preventing recurrent urinary tract infection in children
Cochrane Systematic Reviews, 16-Feb-2011
Urinary tract infection (UTI) is common in children. Symptoms include fever, lethargy, anorexia, and vomiting. UTI is caused by Escherichia coli in over 80% of cases and treatment is a course of antibiotics. Due to acute illness caused by UTI and the risk
- Long-term effects of weight-reducing drugs in people with hypertension
Cochrane Systematic Reviews, 29-Feb-2016
All major guidelines on antihypertensive therapy recommend weight loss; anti-obesity drugs may be able to help in this respect.
- Long-term opioid management for chronic noncancer pain
Cochrane Systematic Reviews, 14-Jan-2016
Opioid therapy for chronic noncancer pain (CNCP) is controversial due to concerns regarding long-term effectiveness and safety, particularly the risk of tolerance, dependence, or abuse.
- Low dosage tricyclic antidepressants for depression
Cochrane Systematic Reviews, 1-Nov-2008
Tricyclic antidepressants are still extensively prescribed worldwide. Evidence for the recommended dosage of tricyclics, however, is poor.
- Low molecular weight heparins versus unfractionated heparin for acute coronary syndromes
Cochrane Systematic Reviews, 2-Aug-2010
Acute coronary syndromes (ACS) are an important source of morbidity and mortality. Despite weak evidence for the use of unfractionated heparin (UFH) for acute coronary syndromes it is considered an accepted treatment for unstable angina and non-ST segment
- Low‐molecular‐weight heparins or heparinoids versus standard unfractionated heparin for acute ischaemic stroke
Cochrane Systematic Reviews, 4-Apr-2017
Low-molecular-weight heparins (LMWHs) and heparinoids are anticoagulants that may have more powerful antithrombotic effects than standard unfractionated heparin (UFH) but a lower risk of bleeding complications. This is an update of the original Cochrane R
- Loxapine for schizophrenia
Cochrane Systematic Reviews, 14-Oct-2015
Some authors have suggested that loxapine is more effective than typical antipsychotics in reducing the negative symptoms of schizophrenia, that extrapyramidal adverse effects are not usually seen at clinically effective antipsychotic doses and that it sh
- Macrolide antibiotics for cystic fibrosis
Cochrane Systematic Reviews, 12-Sep-2012
Macrolide antibiotics may have a modifying role in diseases which involve airway infection and inflammation, like cystic fibrosis.
- Macrolides versus placebo for chronic asthma
Cochrane Systematic Reviews, 22-Nov-2021
Asthma is a chronic disease in which inflammation of the airways causes symptomatic wheezing, coughing and difficult breathing. Macrolides are antibiotics with antimicrobial and anti-inflammatory activities that have been explored for the long-term contro
- Magnesium sulphate and other anticonvulsants for women with pre-eclampsia
Cochrane Systematic Reviews, 29-Sep-2010
Eclampsia, the occurrence of a seizure (fit) in association with pre-eclampsia, is rare but potentially life-threatening. Magnesium sulphate is the drug of choice for treating eclampsia. This review assesses its use for preventing eclampsia.
- Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus
Cochrane Systematic Reviews, 22-Sep-2009
Epidemiological and basic science evidence suggests that magnesium sulphate before birth may be neuroprotective for the fetus.
- Magnesium sulphate versus lytic cocktail for eclampsia
Cochrane Systematic Reviews, 14-Mar-2011
Eclampsia, the occurrence of a seizure in association with pre-eclampsia, is a rare but serious complication of pregnancy. A number of different anticonvulsants have been used to control eclamptic fits and to prevent further seizures.
- Magnesium supplementation in pregnancy
Cochrane Systematic Reviews, 2-Apr-2014
Magnesium is an essential mineral required for regulation of body temperature, nucleic acid and protein synthesis and in maintaining nerve and muscle cell electrical potentials. Many women, especially those from disadvantaged backgrounds, have low intakes
- Maintenance therapy with calcium channel blockers for preventing preterm birth after threatened preterm labour
Cochrane Systematic Reviews, 30-Oct-2013
Calcium channel blocker maintenance therapy is one of the types of tocolytic therapy that may be used after an episode of threatened preterm labour (and usually an initial dose of tocolytic therapy) in an attempt to prevent the onset of further preterm co
- Management of sexual dysfunction due to antipsychotic drug therapy
Cochrane Systematic Reviews, 17-Oct-2012
Psychotropic drugs are associated with sexual dysfunction. Symptoms may concern penile erection, lubrication, orgasm, libido, retrograde ejaculation, sexual arousal, or overall sexual satisfaction. These are major aspects of tolerability and can highly af
- Mast-cell stabilising agents to prevent exercise-induced bronchoconstriction
Cochrane Systematic Reviews, 26-Apr-2009
Exercise-induced bronchoconstriction (or asthma) following strenuous physical exertion is common and can cause sub-optimal performance, symptoms such as cough, dyspnea, wheeze, chest tightness, and can lead people to avoid physical activity. Management fo
- Medical adjuvant treatment to increase patency of arteriovenous fistulae and grafts
Cochrane Systematic Reviews, 16-Jul-2015
End-stage renal disease (ESRD) patients often require either the formation of an arteriovenous (AV) fistula or an AV interposition prosthetic shunt for haemodialysis. These access sites should ideally have a long life and a low rate of complications (for
- Medical interventions for primary open angle glaucoma and ocular hypertension
Cochrane Systematic Reviews, 31-Oct-2008
Primary open angle glaucoma (POAG) is a progressive optic neuropathy with an elevated intraocular pressure (IOP), where the optic nerve head becomes pathologically excavated and the visual field (VF) is characteristically altered. Ocular hypertension (OHT
- Methotrexate as a steroid sparing agent for asthma in adults
Cochrane Systematic Reviews, 29-Sep-2008
Sustained oral corticosteroid use can lead to complications, so there is interest in identifying agents that can reduce oral steroid use in people with asthma. Methotrexate has attracted attention as a possible steroid sparing agent in patients with chron
