Showing 441-460 of 746 for: Cochrane Systematic Reviews > Pharmacotherapeutics
- Macrolide antibiotics for cystic fibrosis
Cochrane Systematic Reviews, 14-Nov-2012
Macrolide antibiotics may have a modifying role in diseases which involve airway infection and inflammation, like cystic fibrosis.
- Macrolides versus placebo for chronic asthma
Cochrane Systematic Reviews, 22-Nov-2021
Asthma is a chronic disease in which inflammation of the airways causes symptomatic wheezing, coughing and difficult breathing. Macrolides are antibiotics with antimicrobial and anti-inflammatory activities that have been explored for the long-term contro
- Magnesium sulphate and other anticonvulsants for women with pre‐eclampsia
Cochrane Systematic Reviews, 10-Nov-2010
Eclampsia, the occurrence of a seizure (fit) in association with pre-eclampsia, is rare but potentially life-threatening. Magnesium sulphate is the drug of choice for treating eclampsia. This review assesses its use for preventing eclampsia.
- Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus
Cochrane Systematic Reviews, 21-Jan-2009
Epidemiological and basic science evidence suggests that magnesium sulphate before birth may be neuroprotective for the fetus.
- Magnesium sulphate versus lytic cocktail for eclampsia
Cochrane Systematic Reviews, 8-Sep-2010
Eclampsia, the occurrence of a seizure in association with pre-eclampsia, is a rare but serious complication of pregnancy. A number of different anticonvulsants have been used to control eclamptic fits and to prevent further seizures.
- Magnesium supplementation in pregnancy
Cochrane Systematic Reviews, 2-Apr-2014
Magnesium is an essential mineral required for regulation of body temperature, nucleic acid and protein synthesis and in maintaining nerve and muscle cell electrical potentials. Many women, especially those from disadvantaged backgrounds, have low intakes
- Maintenance therapy with calcium channel blockers for preventing preterm birth after threatened preterm labour
Cochrane Systematic Reviews, 30-Oct-2013
Calcium channel blocker maintenance therapy is one of the types of tocolytic therapy that may be used after an episode of threatened preterm labour (and usually an initial dose of tocolytic therapy) in an attempt to prevent the onset of further preterm co
- Management of sexual dysfunction due to antipsychotic drug therapy
Cochrane Systematic Reviews, 14-Nov-2012
Psychotropic drugs are associated with sexual dysfunction. Symptoms may concern penile erection, lubrication, orgasm, libido, retrograde ejaculation, sexual arousal, or overall sexual satisfaction. These are major aspects of tolerability and can highly af
- Mast-cell stabilising agents to prevent exercise-induced bronchoconstriction
Cochrane Systematic Reviews, 26-Apr-2009
Exercise-induced bronchoconstriction (or asthma) following strenuous physical exertion is common and can cause sub-optimal performance, symptoms such as cough, dyspnea, wheeze, chest tightness, and can lead people to avoid physical activity. Management fo
- Medical adjuvant treatment to increase patency of arteriovenous fistulae and grafts
Cochrane Systematic Reviews, 23-Jul-2021
People with end-stage renal disease (ESRD) often require either the formation of an arteriovenous fistula (AVF) or an interposition prosthetic arteriovenous graft (AVG) for haemodialysis. These access sites should ideally have a long life and a low rate o
- Medical interventions for primary open angle glaucoma and ocular hypertension
Cochrane Systematic Reviews, 17-Oct-2007
Primary open angle glaucoma (POAG) is a progressive optic neuropathy with an elevated intraocular pressure (IOP), where the optic nerve head becomes pathologically excavated and the visual field (VF) is characteristically altered. Ocular hypertension (OHT
- Methotrexate as a steroid sparing agent for asthma in adults
Cochrane Systematic Reviews, 27-Jul-1998
Sustained oral corticosteroid use can lead to complications, so there is interest in identifying agents that can reduce oral steroid use in people with asthma. Methotrexate has attracted attention as a possible steroid sparing agent in patients with chron
- Methotrexate for induction of remission in refractory Crohn's disease
Cochrane Systematic Reviews, 6-Aug-2014
Although corticosteroids are effective for induction of remission of Crohn's disease, many patients relapse when steroids are withdrawn or become steroid dependent. Furthermore, corticosteroids exhibit significant adverse effects. The success of methotrex
- Methotrexate for maintenance of remission in ulcerative colitis
Cochrane Systematic Reviews, 11-Aug-2015
Methotrexate, a folate antagonist, is an immunosuppressant drug that is effective for treating several inflammatory disorders including Crohn's disease. Ulcerative colitis, a related chronic inflammatory bowel disease, can be challenging to treat. T his u
- Methyldopa for primary hypertension
Cochrane Systematic Reviews, 7-Oct-2009
Hypertension is associated with an increased risk of stroke, myocardial infarction and congestive heart failure. Methyldopa is a centrally acting antihypertensive agent, which was commonly used in the 1970's and 80's for blood pressure control. Its use at
- Methylxanthine treatment for apnoea in preterm infants
Cochrane Systematic Reviews, 25-Feb-2013
Recurrent apnoea is common in preterm infants, particularly at very early gestational ages. These episodes of ineffective breathing can lead to hypoxaemia and bradycardia that may be severe enough to require the use of positive pressure ventilation. Methy
- Methylxanthines for exacerbations of chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 22-Apr-2003
Most international guidelines currently recommend methylxanthines (e.g., theophylline, aminophylline) for severe exacerbations of chronic obstructive pulmonary disease (COPD), yet clinical trials underlying this recommendation have been small and underpow
- Methylxanthines for prolonged non-specific cough in children
Cochrane Systematic Reviews, 8-Nov-2010
Non-specific cough is defined as non-productive cough in the absence of identifiable respiratory disease or known aetiology. It is commonly seen in paediatric practice. These children are treated with a variety of therapies including a variety of asthma m
- Micronutrient supplementation in adults with HIV infection
Cochrane Systematic Reviews, 18-May-2017
Micronutrient deficiencies are common among adults living with HIV disease, particularly in low-income settings where the diet may be low in essential vitamins and minerals. Some micronutrients play critical roles in maintenance of the immune system, and
- Milnacipran versus other antidepressive agents for depression
Cochrane Systematic Reviews, 8-Jul-2009
Although pharmacological and psychological interventions are both effective for major depression, antidepressant drugs are frequently used as first-line treatment in primary and secondary care settings. Milnacipran, a dual serotonin-norepinephrine reuptak