Showing 441-460 of 8668 for: Cochrane Systematic Reviews Back
- Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section
Cochrane Systematic Reviews, 28-Oct-2014
The single most important risk factor for postpartum maternal infection is cesarean section. Although guidelines endorse the use of prophylactic antibiotics for women undergoing cesarean section, there is not uniform implementation of this recommendation.
- Antibiotic regimens for early‐onset neonatal sepsis
Cochrane Systematic Reviews, 17-May-2021
Neonatal sepsis is a major cause of morbidity and mortality. It is the third leading cause of neonatal mortality globally constituting 13% of overall neonatal mortality. Despite the high burden of neonatal sepsis, high-quality evidence in diagnosis and tr
- Antibiotic regimens for late‐onset neonatal sepsis
Cochrane Systematic Reviews, 8-May-2021
Neonatal sepsis is a major cause of morbidity and mortality. It is the third leading cause of neonatal mortality globally constituting 13% of overall neonatal mortality. Despite the high burden of neonatal sepsis, high-quality evidence in diagnosis and tr
- Antibiotic regimens for management of intraamniotic infection
Cochrane Systematic Reviews, 22-Jul-2002
Intraamniotic infection is associated with maternal morbidity and neonatal sepsis, pneumonia and death. Although antibiotic treatment is accepted as the standard of care, few studies have been conducted to examine the effectiveness of different antibiotic
- Antibiotic regimens for management of intra-amniotic infection
Cochrane Systematic Reviews, 19-Dec-2014
Chorioamnionitis is a common infection that affects both mother and infant. Infant complications associated with chorioamnionitis include early neonatal sepsis, pneumonia, and meningitis. Chorioamnionitis can also result in maternal morbidity such as pelv
- Antibiotic regimens for postpartum endometritis
Cochrane Systematic Reviews, 2-Feb-2015
Postpartum endometritis occurs when vaginal organisms invade the endometrial cavity during the labor process and cause infection. This is more common following cesarean birth. The condition warrants antibiotic treatment.
- Antibiotic regimens for secondary peritonitis of gastrointestinal origin in adults
Cochrane Systematic Reviews, 26-Mar-2012
Secondary peritonitis is associated with a high mortality rate and if not treated successfully leads to development of abscesses, severe sepsis and multi-organ failure. Source control and adjunctive antibiotics are the mainstay of treatment. However, no c
- Antibiotic regimens for suspected early neonatal sepsis
Cochrane Systematic Reviews, 18-Oct-2004
Early acquired infection may cause severe illness or death in the neonatal period. Prompt treatment with antibiotics has shown to reduce mortality. It is not clear which antibiotic regimen is suitable for treatment of presumed early neonatal sepsis.
- Antibiotic regimens for suspected late onset sepsis in newborn infants
Cochrane Systematic Reviews, 20-Jul-2005
Late onset neonatal sepsis (systemic infection after 48 hours of age) continues to be a significant cause of morbidity and mortality. Early treatment with antibiotics is essential as infants can deteriorate rapidly. It is not clear which antibiotic regime
- Antibiotic regimens for the empirical treatment of newborn infants with necrotising enterocolitis
Cochrane Systematic Reviews, 9-Jul-2012
Although the exact aetiology of necrotising enterocolitis (NEC) remains unknown, research suggests that it is multifactorial; suspected pathophysiological mechanisms include immaturity, intestinal ischaemia, disruption of intestinal mucosal integrity, for
- Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis
Cochrane Systematic Reviews, 25-Apr-2017
Respiratory tract infection with Pseudomonas aeruginosa occurs in most people with cystic fibrosis. Once chronic infection is established, Pseudomonas aeruginosa is virtually impossible to eradicate and is associated with increased mortality and morbidity
- Antibiotic therapy for adults with neurosyphilis
Cochrane Systematic Reviews, 27-May-2019
Neurosyphilis is an infection of the central nervous system, caused by Treponema pallidum, a spirochete capable of infecting almost any organ or tissue in the body causing neurological complications due to the infection. This disease is a tertiary manifes
- Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis
Cochrane Systematic Reviews, 10-Dec-2021
Cystic fibrosis (CF) a life-limiting inherited disease affecting a number of organs, but classically associated with chronic lung infection and progressive loss of lung function. Chronic infection by Burkholderia cepacia complex (BCC) is associated with i
- Antibiotic therapy for pelvic inflammatory disease
Cochrane Systematic Reviews, 20-Aug-2020
Pelvic inflammatory disease (PID) affects 4% to 12% of women of reproductive age. The main intervention for acute PID is broad-spectrum antibiotics administered intravenously, intramuscularly or orally. We assessed the optimal treatment regimen for PID.
- Antibiotic therapy for preventing infections in people with acute stroke
Cochrane Systematic Reviews, 22-Jan-2018
Stroke is the main cause of disability in high-income countries and ranks second as a cause of death worldwide. Infections occur frequently after stroke and may adversely affect outcome. Preventive antibiotic therapy in the acute phase of stroke may reduc
- Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis
Cochrane Systematic Reviews, 12-May-2010
Pancreatic necrosis may complicate severe acute pancreatitis, and is detectable by computed tomography (CT). If it becomes infected mortality increases, but the use of prophylactic antibiotics raises concerns about antibiotic resistance and fungal infecti
- Antibiotic therapy for Shigella dysentery
Cochrane Systematic Reviews, 8-Aug-2010
Shigella dysentery is a relatively common illness and occasionally causes death, worldwide. Mild symptoms are self-limiting but in more severe cases, antibiotics are recommended for cure and preventing relapse. The antibiotics recommended are diverse, hav
- Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) in non surgical wounds
Cochrane Systematic Reviews, 15-Nov-2013
Non surgical wounds include chronic ulcers (pressure or decubitus ulcers, venous ulcers, diabetic ulcers, ischaemic ulcers), burns and traumatic wounds. The prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonisation (i.e. presence of MR
- Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in surgical wounds
Cochrane Systematic Reviews, 6-Aug-2013
Methicillin-resistant Staphylococcus aureus (MRSA) infection after surgery is usually rare, but incidence can be up to 33% in certain types of surgery. Postoperative MRSA infection can occur as surgical site infections (SSI), chest infections, or bloodstr
- Antibiotic therapy versus no antibiotic therapy for children aged 2 to 59 months with WHO‐defined non‐severe pneumonia and wheeze
Cochrane Systematic Reviews, 20-Jan-2021
Worldwide, pneumonia is the leading cause of death amongst children under five years of age, and accounts for approximately two million deaths annually.