- Lecithin for dementia and cognitive impairment
Cochrane Systematic Reviews, 23-Oct-2000
Alzheimer's disease sufferers have been found to lack the enzyme responsible for converting choline into acetylcholine within the brain. Lecithin is a major dietary source of choline, so extra consumption may reduce the progression of dementia. - Leflunomide for the treatment of rheumatoid arthritis
Cochrane Systematic Reviews, 22-Jul-2002
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease. Leflunomide is one of the more recent oral agents, classified as a disease-modifying antirheumatic drug (DMARD). It has a different mechanism of action than other existing DMARDs. - Legislative smoking bans for reducing harms from secondhand smoke exposure, smoking prevalence and tobacco consumption
Cochrane Systematic Reviews, 4-Feb-2016
Smoking bans have been implemented in a variety of settings, as well as being part of policy in many jurisdictions to protect the public and employees from the harmful effects of secondhand smoke (SHS). They also offer the potential to influence social no - Length of hospitalisation for people with severe mental illness
Cochrane Systematic Reviews, 30-Jan-2014
In high-income countries, over the last three decades, the length of hospital stays for people with serious mental illness has reduced drastically although considerable variation remains. In lower-income countries this variation may be greater. Some argue - Lens extraction for chronic angle‐closure glaucoma
Cochrane Systematic Reviews, 24-Mar-2021
Primary angle-closure glaucoma (PACG) is characterized by a rise in intraocular pressure (IOP) secondary to aqueous outflow obstruction, with relative pupillary block being the most common underlying mechanism. There is increasing evidence that lens extra - Leukodepletion for patients undergoing heart valve surgery
Cochrane Systematic Reviews, 31-Jul-2013
There is some evidence for the benefits of leukodepletion in patients undergoing coronary artery surgery. Its effectiveness in higher risk patients, such as those undergoing heart valve surgery, particularly in terms of overall clinical outcomes, is curre - Leukoreduction for the prevention of adverse reactions from allogeneic blood transfusion
Cochrane Systematic Reviews, 2-Dec-2015
A blood transfusion is an acute intervention, implemented to solve life and health-threatening conditions on a short-term basis. However, blood transfusions have adverse events, some of them potentially related to immune modulation or to a direct transmis - Leukotriene inhibitors for bronchiolitis in infants and young children
Cochrane Systematic Reviews, 16-Mar-2015
Bronchiolitis is an acute inflammatory illness of the bronchioles common among infants and young children. It is often caused by the respiratory syncytial virus (RSV). Management of bronchiolitis varies between clinicians, reflecting the lack of evidence - Leukotriene receptor antagonist for prolonged non‐specific cough in children
Cochrane Systematic Reviews, 19-Apr-2006
Non-specific cough is defined as non-productive cough in the absence of identifiable respiratory disease or known aetiology. It is commonly seen in paediatric practice. These children are treated with a variety of therapies including a variety of asthma m - Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children
Cochrane Systematic Reviews, 19-Oct-2015
Episodic viral wheeze (EVW) associated with viral respiratory tract infections is a common reason for pre-school children to utilise health care resources and for carers to take time away from employment. About a third of children experience a wheezing ep - Leukotriene receptor antagonists for eczema
Cochrane Systematic Reviews, 21-Oct-2018
Eczema is a common, chronic, inflammatory skin condition that is frequently associated with atopic conditions, including asthma. Leukotriene receptor antagonists (LTRAs) have a corticosteroid-sparing role in asthma, but their role in eczema remains contro - Leukotriene receptor antagonists for non‐cystic fibrosis bronchiectasis
Cochrane Systematic Reviews, 24-Apr-2000
Leukotriene receptor antagonists are a new class of drug that were initially identified for use in asthma. As they have an effect on neutrophil mediated inflammation, they may be of benefit in bronchiectasis. - Leukotriene receptor antagonists in addition to usual care for acute asthma in adults and children
Cochrane Systematic Reviews, 2-Apr-2012
Acute asthma presentation in the emergency setting frequently leads to hospital admission. Currently available treatment options include corticosteroid therapy, beta2-agonists and oxygen. Antileukotriene agents are beneficial in chronic asthma as addition - Levetiracetam add‐on for drug‐resistant focal epilepsy
Cochrane Systematic Reviews, 30-Jun-2020
Drug resistance is common in focal epilepsy. In this update, we summarised the current evidence regarding add-on levetiracetam in treating drug-resistant focal epilepsy. The original review was published in 2001 and last updated in 2012. - Levetiracetam for neuropathic pain in adults
Cochrane Systematic Reviews, 7-Jul-2014
Antiepileptic drugs have been used in pain management since the 1960s; some have shown efficacy in treating different neuropathic pain conditions. The efficacy of levetiracetam for relief of neuropathic pain has not previously been reviewed. - Levodopa for the treatment of restless legs syndrome
Cochrane Systematic Reviews, 15-Feb-2011
Levodopa plus dopamine decarboxylase inhibitor is a common treatment for restless legs syndrome (RLS). - Levomepromazine for nausea and vomiting in palliative care
Cochrane Systematic Reviews, 2-Nov-2015
This is an updated version of the original Cochrane Review published in Issue 4, 2013, on Levomepromazine for nausea and vomiting in palliative care. - Levomepromazine for schizophrenia
Cochrane Systematic Reviews, 6-Oct-2010
Levomepromazine is an 'older' typical antipsychotic medication licensed for use in schizophrenia but sparingly prescribed in the United Kingdom. - Levonorgestrel intrauterine system for endometrial protection in women with breast cancer on adjuvant tamoxifen
Cochrane Systematic Reviews, 21-Dec-2020
Adjuvant tamoxifen reduces the risk of breast cancer recurrence in women with oestrogen receptor-positive breast cancer. Tamoxifen also increases the risk of postmenopausal bleeding, endometrial polyps, hyperplasia, and endometrial cancer. The levonorgest - Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery
Cochrane Systematic Reviews, 20-Dec-2021
Endometriosis is a condition characterised by the presence of ectopic deposits of endometrial-like tissue outside the uterus, usually in the pelvis. The impact of laparoscopic treatment on overall pain is uncertain and a significant proportion of women wi
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