Showing 5221-5240 of 7110 for: Cochrane Systematic Reviews Back
- Procaine treatments for cognition and dementia
Cochrane Systematic Reviews, 9-Jun-2010
Procaine is a controversial substance which has been used for "antiageing" effects including cognitive improvement for more than 50 years.
- Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections
Cochrane Systematic Reviews, 23-Jul-2012
Acute respiratory infections (ARIs) comprise a large and heterogeneous group of infections including bacterial, viral and other aetiologies. In recent years, procalcitonin - the prohormone of calcitonin - has emerged as a promising marker for the diagnosi
- Procalcitonin, C-reactive protein, and erythrocyte sedimentation rate for the diagnosis of acute pyelonephritis in children
Cochrane Systematic Reviews, 13-Jan-2015
In children with urinary tract infection (UTI), only those with pyelonephritis (and not cystitis) are at risk for developing long-term renal sequelae. If non-invasive biomarkers could accurately differentiate children with cystitis from children with pyel
- Procarbazine, lomustine and vincristine for recurrent high‐grade glioma
Cochrane Systematic Reviews, 26-Jul-2017
Recurrent high-grade glioma (HGG) carries an extremely poor prognosis. There is no current standard of care or guideline-based recommendations. Nitrosourea-based multidrug chemotherapy or PCV — procarbazine, lomustine (CCNU) and vincristine — is one of th
- Processed versus fresh frozen bone for impaction bone grafting in revision hip arthroplasty
Cochrane Systematic Reviews, 11-Aug-2009
Impaction grafting is a technique to restore bone loss both in the femur and the acetabulum during revision hip arthroplasty surgery. Initially impaction grafting was undertaken using fresh frozen femoral head allografts that were milled to create morseli
- Progestagens and anti-progestagens for pain associated with endometriosis
Cochrane Systematic Reviews, 15-Feb-2012
Endometriosis is a chronic inflammatory condition defined by the presence of glands and stroma outside the uterine cavity. It occurs in 7% to 10% of all women of reproductive age and may present as pain or infertility. The pelvic pain may be in the form o
- Progestational agents for treating threatened or established preterm labour
Cochrane Systematic Reviews, 28-Jan-2014
Prematurity is not only the leading cause of perinatal morbidity and mortality but is associated with long-term impairment. Studies of various tocolytic agents have shown mixed results with little effect in improving pregnancy duration and insufficient da
- Progesterone for acute traumatic brain injury
Cochrane Systematic Reviews, 12-Sep-2012
Traumatic brain injury (TBI) is a leading cause of death and disability. Progesterone is a potential neuroprotective drug to treat patients with TBI.
- Progesterone for premenstrual syndrome
Cochrane Systematic Reviews, 13-Mar-2012
About 5% of women experience severe symptoms called premenstrual syndrome (PMS), only in the two weeks before their menstrual periods. Treatment with progesterone may restore a deficiency, balance menstrual hormone levels or reduce effects of falling prog
- Progesterone for preventing pre-eclampsia and its complications
Cochrane Systematic Reviews, 27-Apr-2011
In the past, progesterone has been advocated for prevention of pre-eclampsia. Although progestogens were never widely used for this purpose in clinical practice, new hypothesis have emerged which suggest progesterone may have a role in promoting immunolog
- Progesterone or progestogen-releasing intrauterine systems for heavy menstrual bleeding
Cochrane Systematic Reviews, 28-Apr-2015
Heavy menstrual bleeding (HMB) is an important cause of ill health in women and it accounts for 12% of all gynaecology referrals in the UK. Heavy menstrual bleeding is clinically defined as greater than or equal to 80 mL of blood loss per menstrual cycle.
- Progesterone receptor modulators for endometriosis
Cochrane Systematic Reviews, 25-Jul-2017
Endometriosis is defined as the presence of endometrial tissue (glands and stroma) outside the uterine cavity. This condition is oestrogen-dependent and thus is seen primarily during the reproductive years. Owing to their antiproliferative effects in the
- Progestin-only contraceptives: effects on weight
Cochrane Systematic Reviews, 18-Jun-2013
Progestin-only contraceptives (POCs) are appropriate for many women who cannot or should not take estrogen. Many POCs are long-acting, cost-effective methods of preventing pregnancy. However, concern about weight gain can deter the initiation of contracep
- Progestin-only pills for contraception
Cochrane Systematic Reviews, 6-Nov-2013
The introduction of a new progestin-only oral contraceptive in Europe has renewed interest in this class of oral contraceptives. Unlike the more widely used combined oral contraceptives containing an estrogen plus progestin, these pills contain only a pro
- Progestogen for preventing miscarriage
Cochrane Systematic Reviews, 18-Oct-2013
Progesterone, a female sex hormone, is known to induce secretory changes in the lining of the uterus essential for successful implantation of a fertilized egg. It has been suggested that a causative factor in many cases of miscarriage may be inadequate se
- Progestogen for treating threatened miscarriage
Cochrane Systematic Reviews, 17-Oct-2011
Miscarriage is a common complication encountered during pregnancy. The role of progesterone in preparing the uterus for the implantation of the embryo and its role in maintaining the pregnancy have been known for a long time. Inadequate secretion of proge
- Progestogen-releasing intrauterine systems versus other forms of reversible contraceptives for contraception
Cochrane Systematic Reviews, 11-Jan-2010
Hormonally impregnated intrauterine systems (IUSs) add a progestogen to a non-medicated contraceptive device to improve contraceptive action.
- Progestogens or progestogen-releasing intrauterine systems for uterine fibroids
Cochrane Systematic Reviews, 29-Jan-2013
Uterine fibroids are the most common premenopausal benign uterine tumours. Fibroids can cause symptoms including heavy menstrual bleeding, pelvic pressure and pain. Progestogens can be administered by various routes. Intramuscular injection of depot medro
- Progestogens with or without oestrogen for irregular uterine bleeding associated with anovulation
Cochrane Systematic Reviews, 12-Sep-2012
Irregular menstrual bleeding may arise due to exogenous sex steroids, lesions of the genital tract or be associated with anovulation. Irregular bleeding due to oligo/anovulation (previously called dysfunctional uterine bleeding or DUB) is more common at t
- Prognostic value of test(s) for O6‐methylguanine–DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma treated with temozolomide
Cochrane Systematic Reviews, 12-Mar-2021
Glioblastoma is an aggressive form of brain cancer. Approximately five in 100 people with glioblastoma survive for five years past diagnosis. Glioblastomas that have a particular modification to their DNA (called methylation) in a particular region (the O
