- Needling for encapsulated trabeculectomy filtering blebs
Cochrane Systematic Reviews, 15-Aug-2012
Encapsulation of a filtering bleb following trabeculectomy may lead to elevation of intraocular pressure, prompting further medical or surgical intervention. It has been suggested that needling of an encapsulated bleb may be effective in re-establishing d - Negative pressure wound therapy for managing the open abdomen in non‐trauma patients
Cochrane Systematic Reviews, 6-May-2022
Management of the open abdomen is a considerable burden for patients and healthcare professionals. Various temporary abdominal closure techniques have been suggested for managing the open abdomen. In recent years, negative pressure wound therapy (NPWT) ha - Negative pressure wound therapy for open traumatic wounds
Cochrane Systematic Reviews, 3-Jul-2018
Traumatic wounds (wounds caused by injury) range from abrasions and minor skin incisions or tears, to wounds with extensive tissue damage or loss as well as damage to bone and internal organs. Two key types of traumatic wounds considered in this review ar - Negative pressure wound therapy for partial‐thickness burns
Cochrane Systematic Reviews, 15-Dec-2014
A burn wound is a complex and evolving injury, with both local and systemic consequences. Burn treatments include a variety of dressings, as well as newer strategies, such as negative pressure wound therapy (NPWT), which, by means of a suction force that - Negative pressure wound therapy for surgical wounds healing by primary closure
Cochrane Systematic Reviews, 26-Apr-2022
Indications for the use of negative pressure wound therapy (NPWT) are broad and include prophylaxis for surgical site infections (SSIs). Existing evidence for the effectiveness of NPWT on postoperative wounds healing by primary closure remains uncertain. - Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus
Cochrane Systematic Reviews, 17-Oct-2018
Foot wounds in people with diabetes mellitus (DM) are a common and serious global health issue. People with DM are prone to developing foot ulcers and, if these do not heal, they may also undergo foot amputation surgery resulting in postoperative wounds. - Negative pressure wound therapy for treating leg ulcers
Cochrane Systematic Reviews, 14-Jul-2015
Leg ulcers are open skin wounds that occur between the ankle and the knee that can last weeks, months or even years and are a consequence of arterial or venous valvular insufficiency. Negative pressure wound therapy (NPWT) is a technology that is currentl - Negative pressure wound therapy for treating pressure ulcers
Cochrane Systematic Reviews, 2-Jun-2015
Pressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Negative pressure wound therapy (NPWT) is a treatment option for pressure ulcers; a clear, curren - Negative pressure wound therapy for treating surgical wounds healing by secondary intention
Cochrane Systematic Reviews, 29-May-2015
Following surgery, incisions are usually closed by fixing the edges together with sutures (stitches), staples, adhesive glue or clips. This process helps the cut edges heal together and is called 'healing by primary intention'. However, not all incised wo - Neo-adjuvant and adjuvant hormone therapy for localised and locally advanced prostate cancer
Cochrane Systematic Reviews, 3-Jun-2009
Hormone therapy for early prostate cancer has demonstrated an improvement in clinical and pathological variables, but not always an improvement in overall survival. We performed a systematic review of both adjuvant and neo-adjuvant hormone therapy combine - Neoadjuvant and adjuvant therapy for surgical resection of hepatocellular carcinoma
Cochrane Systematic Reviews, 21-Jan-2009
Hepatocellular carcinoma is a disease of great concern. Surgery is the treatment of choice, but there is still a high recurrence rate after resection. - Neoadjuvant chemotherapy before surgery versus surgery followed by chemotherapy for initial treatment in advanced ovarian epithelial cancer
Cochrane Systematic Reviews, 30-Jul-2021
Epithelial ovarian cancer presents at an advanced stage in the majority of women. These women require a combination of surgery and chemotherapy for optimal treatment. Conventional treatment has been to perform surgery first and then give chemotherapy. How - Neoadjuvant chemotherapy for locally advanced cervix cancer
Cochrane Systematic Reviews, 19-Apr-2004
The impact of neoadjuvant chemotherapy in the treatment of locally advanced cervical cancer remains uncertain. - Neoadjuvant chemotherapy plus surgery versus surgery for cervical cancer
Cochrane Systematic Reviews, 12-Dec-2012
A previous systematic review found that giving neoadjuvant chemotherapy before surgery improved survival compared with radiotherapy. However, the role of neoadjuvant chemotherapy followed by surgery versus surgery alone is still unclear. - Neoadjuvant chemotherapy versus none for resectable gastric cancer
Cochrane Systematic Reviews, 29-Oct-2008
Gastric cancer is a major cause of cancer death, and many patients are only diagnosed when the cancer has reached an advanced stage. Neoadjuvant chemotherapy (NAC), that is, chemotherapy administered shortly before surgical treatment, could provide a meth - Neoadjuvant treatment for stage III and IV cutaneous melanoma
Cochrane Systematic Reviews, 17-Jan-2023
Cutaneous melanoma is amongst the most aggressive of all skin cancers. Neoadjuvant treatment is a form of induction therapy, given to shrink a cancerous tumour prior to the main treatment (usually surgery). The purpose is to improve survival and surgical - Neonatal interventions for preventing cerebral palsy: an overview of Cochrane Systematic Reviews
Cochrane Systematic Reviews, 20-Jun-2018
Cerebral palsy is an umbrella term that encompasses disorders of movement and posture attributed to non-progressive disturbances occurring in the developing foetal or infant brain. As there are diverse risk factors and aetiologies, no one strategy will pr - Neonatal screening for sickle cell disease
Cochrane Systematic Reviews, 24-Jan-2000
Sickle cell disease is an inherited disorder that occurs throughout the world with its highest incidence in areas of Africa where malaria is endemic. It affects up to 1 in 60 infants born in some areas of Africa. There are a number of potentially serious - Neonatal vitamin A supplementation for the prevention of mortality and morbidity in term neonates in low and middle income countries
Cochrane Systematic Reviews, 24-Feb-2017
Vitamin A deficiency is a major public health problem in low and middle income countries. Vitamin A supplementation in children six months of age and older has been found to be beneficial, but no effect of supplementation has been noted for children betwe - Neostigmine for reversal of neuromuscular block in paediatric patients
Cochrane Systematic Reviews, 30-Apr-2014
Residual neuromuscular block is associated with serious postoperative complications. Some anaesthesiologists use neostigmine to reverse neuromuscular blockade for all paediatric surgical patients. However, the incidence of residual neuromuscular block may
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