Showing 5321-5340 of 7110 for: Cochrane Systematic Reviews Back
- Propylthiouracil for alcoholic liver disease
Cochrane Systematic Reviews, 11-May-2011
Randomised clinical trials have addressed the question whether propylthiouracil has any beneficial effects in patients with alcoholic liver disease.
- Prostacyclin and analogues for acute ischaemic stroke
Cochrane Systematic Reviews, 16-Sep-2008
Prostacyclin is an agent with a number of effects on platelets, blood vessels and nerve cells which might improve outcome after acute ischaemic stroke.
- Prostacyclin for pulmonary hypertension in adults
Cochrane Systematic Reviews, 29-Mar-2009
Primary pulmonary hypertension (PPH) is progressive, resulting in right ventricular failure. Pulmonary hypertension can be idiopathic or associated with other conditions. Prostacyclin is a potent vasodilator and inhibitor of platelet aggregation, and can
- Prostaglandin E1 for preventing the progression of diabetic kidney disease
Cochrane Systematic Reviews, 24-Mar-2010
Diabetic kidney disease (DKD) is one of the major chronic microvascular complications in diabetes mellitus, and may progress to end-stage kidney disease (ESKD). There are no definitely effective approaches for preventing, delaying or treating DKD. Small s
- Prostaglandin E1 for treatment of erectile dysfunction
Cochrane Systematic Reviews, 18-Sep-2008
Erectile dysfunction (ED), the inability to achieve or maintain an erection sufficient for satisfactory sexual activity, is one of the most common sexual dysfunctions in men. ED may have a dramatic impact on the quality of life of many men and their partn
- Prostaglandins before caesarean section for preventing neonatal respiratory distress
Cochrane Systematic Reviews, 11-Nov-2013
Respiratory distress (RD) can occur in both preterm and term neonates born through normal vaginal delivery or caesarean section (CS). It accounts for about 30% of neonatal deaths and can occur at any time following birth. Respiratory distress syndrome (RD
- Prostaglandins for adult liver transplanted patients
Cochrane Systematic Reviews, 6-Sep-2011
Prostaglandins may reduce ischaemic injury after liver transplantation. Several small randomised trials have evaluated the effects of prostaglandins in patients undergoing liver transplantation. Results of these trials are inconsistent, and none has enoug
- Prostaglandins for management of retained placenta
Cochrane Systematic Reviews, 13-May-2014
Retained placenta affects 0.5% to 3% of women following delivery and it is a major cause of maternal death due to postpartum haemorrhage. Usually, retained placenta has been managed by manual removal or curettage under anaesthesia, which may be associated
- Prostaglandins for prelabour rupture of membranes at or near term
Cochrane Systematic Reviews, 6-Nov-2008
Induction of labour after prelabour rupture of membranes may reduce the risk of neonatal infection. However an expectant approach may be less likely to result in caesarean section.
- Prostaglandins for preventing postpartum haemorrhage
Cochrane Systematic Reviews, 10-Jul-2012
Prostaglandins have mainly been used for postpartum haemorrhage (PPH) when other measures fail. Misoprostol, a new and inexpensive prostaglandin E1 analogue, has been suggested as an alternative for routine management of the third stage of labour.
- Prostaglandins versus oxytocin for prelabour rupture of membranes at or near term
Cochrane Systematic Reviews, 6-Nov-2008
The conventional method of induction of labour is with intravenous oxytocin. More recently, induction with prostaglandins, followed by an infusion of oxytocin if necessary, has been used.
- Prostaglandins versus oxytocin for prelabour rupture of membranes at term
Cochrane Systematic Reviews, 6-Nov-2008
The conventional method of induction of labour is with intravenous oxytocin. More recently, induction with prostaglandins, followed by an infusion of oxytocin if necessary, has been used.
- Prostanoids and their analogues for the treatment of pulmonary hypertension in neonates
Cochrane Systematic Reviews, 1-Oct-2019
Persistent pulmonary hypertension of the newborn (PPHN) is a disease entity that describes a physiology in which there is persistence of increased pulmonary arterial pressure. PPHN is characterised by failure to adapt to a functional postnatal circulation
- Prostanoids for critical limb ischaemia
Cochrane Systematic Reviews, 16-Feb-2010
Peripheral arterial occlusive disease (PAOD) is a common cause of morbidity and mortality due to cardiovascular diseases in the general population. While numerous treatments have been adopted for different disease stages, there is no option other than amp
- Prostanoids for intermittent claudication
Cochrane Systematic Reviews, 14-Mar-2013
Peripheral arterial disease (PAD) is a common cause of morbidity in the general population. While numerous studies have established the efficacy of prostanoids in PAD stages III and IV, the question of the role of prostanoids as an alternative or additive
- Prosthetic mesh placement for the prevention of parastomal herniation
Cochrane Systematic Reviews, 20-Jul-2018
Parastomal herniation is a common problem following formation of a stoma after both elective and emergency abdominal surgery. Symptomatic hernias give rise to a significant amount of patient morbidity, and in some cases mortality, and therefore may necess
- Prosthetic rehabilitation for older dysvascular people following a unilateral transfemoral amputation
Cochrane Systematic Reviews, 20-Jan-2015
Dysvascularity accounts for 75% of all lower limb amputations in the UK. Around 37% of these are at transfemoral level (mid-thigh), with the majority of people being over the age of 60 and having existing co-morbidities. A significant number of these ampu
- Protease activity as a prognostic factor for wound healing in venous leg ulcers
Cochrane Systematic Reviews, 1-Sep-2018
Venous leg ulcers (VLUs) are a common type of complex wound that have a negative impact on people's lives and incur high costs for health services and society. It has been suggested that prolonged high levels of protease activity in the later stages of th
- Protein and energy supplementation in elderly people at risk from malnutrition
Cochrane Systematic Reviews, 17-Feb-2009
Evidence for the effectiveness of nutritional supplements containing protein and energy, often prescribed for older people, is limited. Malnutrition is more common in this age group and deterioration of nutritional status can occur during illness. It is i
- Protein containing synthetic surfactant versus animal derived surfactant extract for the prevention and treatment of respiratory distress syndrome
Cochrane Systematic Reviews, 23-Sep-2008
Respiratory distress syndrome (RDS) is a significant cause of morbidity and mortality in preterm infants. RDS is caused by a deficiency, dysfunction, or inactivation of pulmonary surfactant. Numerous surfactants of either animal extract or synthetic desig