- Antibiotics for the treatment of COVID‐19
Cochrane Systematic Reviews, 22-Oct-2021
The effect of antibiotics with potential antiviral and anti-inflammatory properties are being investigated in clinical trials as treatment for COVID-19. The use of antibiotics follows the intention-to-treat the viral disease and not primarily to treat bac - Antibiotics for trachoma
Cochrane Systematic Reviews, 25-Sep-2019
Trachoma is the world's leading infectious cause of blindness. In 1996, WHO launched the Alliance for the Global Elimination of Trachoma by the year 2020, based on the 'SAFE' strategy (surgery, antibiotics, facial cleanliness, and environmental improvemen - Antibiotics for treating acute chest syndrome in people with sickle cell disease
Cochrane Systematic Reviews, 18-Sep-2019
The clinical presentation of acute chest syndrome is similar whether due to infectious or non-infectious causes, thus antibiotics are usually prescribed to treat all episodes. Many different pathogens, including bacteria, have been implicated as causative - Antibiotics for treating bacterial vaginosis in pregnancy
Cochrane Systematic Reviews, 27-Nov-2012
Bacterial vaginosis is an imbalance of the normal vaginal flora with an overgrowth of anaerobic bacteria and a lack of the normal lactobacillary flora. Women may have symptoms of a characteristic vaginal discharge but are often asymptomatic. Bacterial vag - Antibiotics for treating chronic osteomyelitis in adults
Cochrane Systematic Reviews, 17-Dec-2013
Chronic osteomyelitis is generally treated with antibiotics and surgical debridement but can persist intermittently for years with frequent therapeutic failure or relapse. Despite advances in both antibiotic and surgical treatment, the long-term recurrenc - Antibiotics for treating community‐acquired pneumonia in people with sickle cell disease
Cochrane Systematic Reviews, 14-Nov-2016
As a consequence of their condition, people with sickle cell disease are at high risk of developing an acute infection of the pulmonary parenchyma called community-acquired pneumonia. Many different bacteria can cause this infection and antibiotic treatme - Antibiotics for treating gonorrhoea in pregnancy
Cochrane Systematic Reviews, 21-Feb-2018
Gonorrhoea is a sexually transmitted infection that is caused by Neisseria gonorrhoeae, and is a major public health challenge today. N gonorrhoeae can be transmitted from the mother’s genital tract to the newborn during birth, and can cause gonococcal op - Antibiotics for treating human brucellosis
Cochrane Systematic Reviews, 22-Aug-2012
Brucellosis is the most common zoonotic infection in the world. Several antibiotics, separately or in combination, have been tried for treatment of human brucellosis. The inconsistencies between different treatment regimens warrants the need for a systema - Antibiotics for treating lower urinary tract infection in children
Cochrane Systematic Reviews, 22-Jul-2014
Urinary tract infection (UTI) is one of the most common bacterial infections in infants and children. Lower UTI is the most commonly presenting and in the majority of cases can be easily treated with a course of antibiotic therapy with no further complica - Antibiotics for treating osteomyelitis in people with sickle cell disease
Cochrane Systematic Reviews, 7-Oct-2019
Osteomyelitis (both acute and chronic) is one of the most common infectious complications in people with sickle cell disease. There is no standardized approach to antibiotic therapy and treatment is likely to vary from country to country. Thus, there is a - Antibiotics for treating scrub typhus
Cochrane Systematic Reviews, 24-Sep-2018
Scrub typhus, an important cause of acute fever in Asia, is caused by Orientia tsutsugamushi, an obligate intracellular bacterium. Antibiotics currently used to treat scrub typhus include tetracyclines, chloramphenicol, macrolides, and rifampicin. - Antibiotics for treating septic abortion
Cochrane Systematic Reviews, 30-Jun-2016
A septic abortion refers to any abortion (spontaneous or induced) complicated by upper genital tract infection including endometritis or parametritis. The mainstay of treatment of septic abortion is antibiotic therapy alone or in combination with evacuati - Antibiotics for treating urogenital Chlamydia trachomatis infection in men and non‐pregnant women
Cochrane Systematic Reviews, 25-Jan-2019
The genital infection caused by Chlamydia trachomatis (CT) is a common sexually transmitted infection (STI) globally. The infection is mainly asymptomatic in women, thus it can produce infertility and chronic pelvic pain. In men infection is mainly sympto - Antibiotics for treatment of sore throat in children and adults
Cochrane Systematic Reviews, 9-Dec-2021
Sore throat is a common reason for people to present for medical care and to be prescribed antibiotics. Overuse of antibiotics in primary medicine is a concern, hence it is important to establish their efficacy in treating sore throat and preventing secon - Antibiotics for uncomplicated diverticulitis
Cochrane Systematic Reviews, 15-Oct-2012
Diverticulitis is an inflammatory complication to the very common condition diverticulosis. Uncomplicated diverticulitis has traditionally been treated with antibiotics with reference to the microbiology, extrapolation from trials on complicated intra-abd - Antibiotics for ureaplasma in the vagina in pregnancy
Cochrane Systematic Reviews, 7-Sep-2011
Preterm birth is a significant perinatal problem contributing to perinatal morbidity and mortality. Heavy vaginal ureaplasma colonisation is suspected of playing a role in preterm birth and preterm rupture of the membranes. Antibiotics are used to treat i - Antibiotics for ventilator-associated pneumonia
Cochrane Systematic Reviews, 20-Oct-2016
Ventilator-associated pneumonia (VAP) is a significant cause of morbidity and mortality, complicating the medical course of approximately 10% of mechanically-ventilated patients, with an estimated attributable mortality of 13%. To treat VAP empirically, t - Antibiotics for whooping cough (pertussis)
Cochrane Systematic Reviews, 10-Feb-2013
Whooping cough is a highly contagious respiratory disease. Infants are at highest risk of severe disease and death. Erythromycin for 14 days is currently recommended for treatment and contact prophylaxis but its benefit is uncertain. - Antibiotics prior to amniotomy for reducing infectious morbidity in mother and infant
Cochrane Systematic Reviews, 1-Oct-2014
Amniotomy (the deliberate rupture of membranes) was described almost two centuries ago and since then has been used both for induction and augmentation of labour - which are common obstetric practices. Trends have shown a rise in the induction rates over - Antibiotics prior to embryo transfer in ART
Cochrane Systematic Reviews, 14-Feb-2012
Embryo transfer (ET) involves the placement of one or more embryos into the uterine cavity, usually by passing a catheter through the cervical os. ET is the final step in an assisted reproductive technology (ART) cycle, where a woman has undergone control
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