- Operative versus conservative management for 'fetal distress' in labour
Cochrane Systematic Reviews, 13-Jun-2012
Suspected fetal distress usually results in expedited delivery of a baby (often operatively). The potential harm to a mother and baby from operative delivery may not always be justified especially when fetal distress may be misdiagnosed. Even with a corre - Opioid agonist treatment for pharmaceutical opioid dependent people
Cochrane Systematic Reviews, 4-May-2016
There are increasing concerns regarding pharmaceutical opioid harms including overdose and dependence, with an associated increase in treatment demand. People dependent on pharmaceutical opioids appear to differ in important ways from people who use heroi - Opioid antagonists for alcohol dependence
Cochrane Systematic Reviews, 17-Oct-2010
Alcohol dependence belongs to the globally leading health risk factors. Therapeutic success of psychosocial programs for relapse prevention is moderate and could be increased by an adjuvant treatment with the opioid antagonists naltrexone and nalmefene. - Opioid antagonists for smoking cessation
Cochrane Systematic Reviews, 23-May-2013
The reinforcing properties of nicotine may be mediated through release of various neurotransmitters both centrally and systemically. People who smoke report positive effects such as pleasure, arousal, and relaxation as well as relief of negative affect, t - Opioid antagonists under heavy sedation or anaesthesia for opioid withdrawal
Cochrane Systematic Reviews, 20-Jan-2010
Withdrawal (detoxification) is necessary prior to drug-free treatment or as the end point of long-term substitution treatment. - Opioid antagonists with minimal sedation for opioid withdrawal
Cochrane Systematic Reviews, 29-May-2017
Managed withdrawal is a necessary step prior to drug-free treatment or as the endpoint of long-term substitution treatment. - Opioid switching to improve pain relief and drug tolerability
Cochrane Systematic Reviews, 27-Nov-2015
Patients with cancer, and increasingly chronic non-cancer pain frequently require strong opioids for pain relief. Morphine is the first-line strong opioid of choice for these patients. While most achieve adequate analgesia with morphine, a significant min - Opioid therapy for treating rheumatoid arthritis pain
Cochrane Systematic Reviews, 2-Oct-2011
Despite improvements in the management of rheumatoid arthritis (RA), pain control is often inadequate even when inflammation is well controlled. - Opioid treatment for opioid withdrawal in newborn infants
Cochrane Systematic Reviews, 7-Jul-2021
Neonatal abstinence syndrome (NAS) due to opioid withdrawal may result in disruption of the mother-infant relationship, sleep-wake abnormalities, feeding difficulties, weight loss, seizures and neurodevelopmental problems. - Opioids compared to placebo or other treatments for chronic low‐back pain
Cochrane Systematic Reviews, 27-Aug-2013
The use of opioids in the long-term management of chronic low-back pain (CLBP) has increased dramatically. Despite this trend, the benefits and risks of these medications remain unclear. This review is an update of a Cochrane review first published in 200 - Opioids for acute pancreatitis pain
Cochrane Systematic Reviews, 25-Jul-2013
Acute pancreatitis is an acute inflammatory process of the pancreas that may also involve adjacent tissues and/or remote organ systems. Abdominal pain is the main symptom and is usually accompanied by nausea, vomiting and fever. Opoids are commonly used t - Opioids for agitation in dementia
Cochrane Systematic Reviews, 7-May-2015
Agitation is a common experience for people living with dementia, particularly as day-to-day function and cognition start to decline more. At the present time there are limited pharmacological options for relieving agitation and little is known about the - Opioids for cancer pain ‐ an overview of Cochrane reviews
Cochrane Systematic Reviews, 6-Jul-2017
Pain is a common symptom with cancer, and 30% to 50% of all people with cancer will experience moderate to severe pain that can have a major negative impact on their quality of life. Opioid (morphine-like) drugs are commonly used to treat moderate or seve - Opioids for cancer‐related pain in children and adolescents
Cochrane Systematic Reviews, 19-Jul-2017
Pain is a common feature of childhood and adolescence around the world, and for many young people, that pain is chronic. The World Health Organization (WHO) guidelines for pharmacological treatments for children's persisting pain acknowledge that pain in - Opioids for chronic non‐cancer pain in children and adolescents
Cochrane Systematic Reviews, 26-Jul-2017
Pain is a common feature of childhood and adolescence around the world, and for many young people, that pain is chronic. The World Health Organization guidelines for pharmacological treatments for children's persisting pain acknowledge that pain in childr - Opioids for neonates receiving mechanical ventilation
Cochrane Systematic Reviews, 23-Jan-2008
Mechanical ventilation is a potentially painful and discomforting intervention widely used in neonatal intensive care units. Newborn babies (neonates) demonstrate increased sensitivity to pain, which may affect clinical and neurodevelopmental outcomes. Th - Opioids for neuropathic pain
Cochrane Systematic Reviews, 29-Aug-2013
This is an updated version of the original Cochrane review published in Issue 3, 2006, which included 23 trials. The use of opioids for neuropathic pain remains controversial. Studies have been small, have yielded equivocal results, and have not establish - Opioids for newborn infants receiving mechanical ventilation
Cochrane Systematic Reviews, 17-Mar-2021
Mechanical ventilation is a potentially painful and discomforting intervention that is widely used in neonatal intensive care. Newborn infants demonstrate increased sensitivity to pain, which may affect clinical and neurodevelopmental outcomes. The use of - Opioids for restless legs syndrome
Cochrane Systematic Reviews, 29-Jun-2016
Restless legs syndrome (RLS) is a distressing and common neurological disorder that may have a huge impact in the quality of life of those with frequent and intense symptoms. Patients complain of unpleasant sensations in the legs, at or before bedtime, an - Opioids for the management of breakthrough pain in cancer patients
Cochrane Systematic Reviews, 12-Oct-2015
This review is an update of a previously published review in the Cochrane Database of Systematic Reviews (Issue 1, 2006). Breakthrough pain is a transient exacerbation of pain that occurs either spontaneously or in relation to a specific predictable or un
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