Showing 541-560 of 753 for: Cochrane Systematic Reviews > Pharmacotherapeutics 
- Parasympathomimetic drugs for the treatment of salivary gland dysfunction due to radiotherapy
Cochrane Systematic Reviews, 12-Oct-2015
This is an updated version of the original Cochrane review on parasympathomimetic drugs for the treatment of salivary gland dysfunction due to radiotherapy (published in Issue 3, 2007). Salivary gland dysfunction is a predictable side effect of radiothera
- Parenteral anticoagulation in ambulatory patients with cancer
Cochrane Systematic Reviews, 11-Sep-2017
Anticoagulation may improve survival in patients with cancer through a speculated anti-tumour effect, in addition to the antithrombotic effect, although may increase the risk of bleeding.
- Parent-initiated oral corticosteroid therapy for intermittent wheezing illnesses in children
Cochrane Systematic Reviews, 25-Nov-2008
Intermittent wheezing illnesses, which include viral associated wheeze and asthma, are amongst the most common reasons for children to present urgently to a doctor. Whether parents should commence oral corticosteroids (OCS) for an episode of acute wheeze
- Patient controlled opioid analgesia versus non-patient controlled opioid analgesia for postoperative pain
Cochrane Systematic Reviews, 10-Jun-2015
This is an updated version of the original Cochrane review published in Issue 4, 2006. Patients may control postoperative pain by self administration of intravenous opioids using devices designed for this purpose (patient controlled analgesia or PCA). A 1
- Pentoxifylline for treatment of sepsis and necrotizing enterocolitis in neonates
Cochrane Systematic Reviews, 9-Mar-2015
Mortality and morbidity due to neonatal sepsis and necrotizing enterocolitis (NEC) remain high despite the use of potent antimicrobial agents. Agents that modulate inflammation may improve outcomes. Pentoxifylline, a phosphodiesterase inhibitor, is one su
- Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke
Cochrane Systematic Reviews, 16-Sep-2008
Methylxanthine derivatives are vasodilators. They also inhibit platelet aggregation and thromboxane A2 synthesis, decrease the release of free radicals and may be neuroprotective. This review covers an area where no active research is taking place. It wil
- Perazine for schizophrenia
Cochrane Systematic Reviews, 14-Jan-2014
Perazine is an old phenothiazine derivative used for the treatment of people with schizophrenia and is reputed to have a low level of extrapyramidal adverse effects. As far as we are aware, its use is limited to Germany, Poland, the former Yugoslavia and
- Peri‐implantation glucocorticoid administration for assisted reproductive technology cycles
Cochrane Systematic Reviews, 30-Jun-2022
The use of peri-implantation glucocorticoids has been advocated to improve embryo implantation during assistive reproductive technology (ART) cycles such as in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI). It has been proposed that
- Perioperative local anaesthesia for reducing pain following tonsillectomy
Cochrane Systematic Reviews, 10-Nov-2008
Pain relief after tonsillectomy is an important part of post-operative management. Sometimes local anaesthetics are administed to the tonsillar region, but their effectiveness in relieving pain has not been formally assessed.
- Perphenazine for schizophrenia
Cochrane Systematic Reviews, 5-Mar-2015
Perphenazine is an old phenothiazine antipsychotic with a potency similar to haloperidol. It has been used for many years and is popular in the northern European countries and Japan.
- Pharmaceutical policies: effects of restrictions on reimbursement
Cochrane Systematic Reviews, 7-Jul-2010
Public policy makers and benefit plan managers need to restrain rising pharmaceutical drug costs while preserving access and optimizing health benefits.
- Pharmacological cardioversion for atrial fibrillation and flutter
Cochrane Systematic Reviews, 8-Sep-2008
Atrial fibrillation is the commonest cardiac dysrhythmia. It is associated with significant morbidity and mortality. There are two approaches to the management of atrial fibrillation: controlling the ventricular rate or converting to sinus rhythm in the e
- Pharmacological interventions for benzodiazepine mono-dependence management in outpatient settings
Cochrane Systematic Reviews, 18-Jun-2013
The items with X are considered "more relevant", that is the review has to stick to them to allow publication. The others have to be considered as strong suggestions to improve the readability and clarity of the review, but the reviewers can consider if
- Pharmacological interventions for borderline personality disorder
Cochrane Systematic Reviews, 11-May-2010
Drugs are widely used in borderline personality disorder (BPD) treatment, chosen because of properties known from other psychiatric disorders ("off-label use"), mostly targeting affective or impulsive symptom clusters.
- Pharmacological interventions for epilepsy in people with intellectual disabilities
Cochrane Systematic Reviews, 2-Sep-2015
The prevalence of epilepsy among people with intellectual disabilities is much higher than in the general population. Seizures in this population are often complex and refractory to treatment and antiepileptic medication may have a profound effect upon be
- Pharmacological interventions for hypertensive emergencies
Cochrane Systematic Reviews, 12-Nov-2008
Hypertensive emergencies, marked hypertension associated with acute end-organ damage, are life-threatening conditions. Many anti-hypertensive drugs have been used in these clinical settings. The benefits and harms of such treatment and the best first-line
- Pharmacological management for agitation and aggression in people with acquired brain injury
Cochrane Systematic Reviews, 13-May-2008
Of the many psychiatric symptoms that may result from brain injury, agitation and/or aggression are often the most troublesome. It is therefore important to evaluate the efficacy of psychotropic medication used in its management.
- Pharmacological treatment for psychotic depression
Cochrane Systematic Reviews, 16-Jul-2015
Evidence is limited regarding the most effective pharmacological treatment for psychotic depression: combination of an antidepressant plus an antipsychotic, monotherapy with an antidepressant or monotherapy with an antipsychotic. This is an update of a re
- Pharmacological treatments for psychosis-related polydipsia
Cochrane Systematic Reviews, 3-May-2012
Polydipsia is the intake of more than three litres of fluids per day. Primary polydipsia occurs when excessive drinking cannot be explained by an identified medical condition, and is not secondary to polyuria. The prevalence of this problem in psychiatric
- Pharmacotherapy augmentation strategies in treatment-resistant anxiety disorders
Cochrane Systematic Reviews, 2-Nov-2008
A large proportion of patients with anxiety disorders fail to respond to first-line medication interventions, despite evidence of the effectiveness of these agents.
