Showing 561-580 of 639 for: Cochrane Systematic Reviews > Cardiovascular 
- Statins for children with familial hypercholesterolemia
Cochrane Systematic Reviews, 7-Nov-2019
Familial hypercholesterolemia is one of the most common inherited metabolic diseases and is an autosomal dominant disorder meaning heterozygotes, or carriers, are affected. Those who are homozygous have severe disease. The average worldwide prevalence of
- Statins for primary prevention of venous thromboembolism
Cochrane Systematic Reviews, 18-Dec-2014
Venous thromboembolism (VTE) is common in clinical practice. The efficacy of statins in the primary prevention of VTE remains unproven. This is an update of the review first published in 2011.
- Statins for the prevention of dementia
Cochrane Systematic Reviews, 4-Jan-2016
This is an update of a Cochrane review first published in 2001 and then updated in 2009. Vascular risk factors including high cholesterol levels increase the risk of dementia due to Alzheimer's disease and of vascular dementia. Some observational studies
- Statins for the primary prevention of cardiovascular disease
Cochrane Systematic Reviews, 31-Jan-2013
Reducing high blood cholesterol, a risk factor for cardiovascular disease (CVD) events in people with and without a past history of CVD is an important goal of pharmacotherapy. Statins are the first-choice agents. Previous reviews of the effects of statin
- Stem cell transplantation for ischemic stroke
Cochrane Systematic Reviews, 5-May-2019
Stroke is a leading cause of morbidity and mortality worldwide, with very large healthcare and social costs, and a strong demand for alternative therapeutic approaches. Preclinical studies have shown that stem cells transplanted into the brain can lead to
- Stent placement versus surgery for coarctation of the thoracic aorta
Cochrane Systematic Reviews, 3-Apr-2012
Coarctation of the aorta (CoA) accounts for 5% to 7% of congenital heart disease, with an incidence of 0.3 to 0.4 per 1000 live births. Surgery was the only choice of therapy for CoA until 1982 when balloon angioplasty became an available alternative for
- Steroid sex hormones for lower limb atherosclerosis
Cochrane Systematic Reviews, 17-Oct-2012
There is accumulating evidence that steroid sex hormones have a beneficial effect on a number of risk factors for peripheral arterial disease.
- Steroids, radiotherapy, chemotherapy and stents for superior vena caval obstruction in carcinoma of the bronchus
Cochrane Systematic Reviews, 9-Mar-2015
Superior vena caval obstruction (SVCO) is an uncommon manifestation of carcinoma of the bronchus characterised by neck swelling and distended veins over the chest. Treatment options include radiotherapy, chemotherapy, steroids and insertion of an expandab
- Stretching to prevent or reduce muscle soreness after exercise
Cochrane Systematic Reviews, 6-Jul-2011
Many people stretch before or after engaging in athletic activity. Usually the purpose is to reduce risk of injury, reduce soreness after exercise, or enhance athletic performance. This is an update of a Cochrane review first published in 2007.
- Stroke liaison workers for stroke patients and carers: an individual patient data meta-analysis
Cochrane Systematic Reviews, 30-Mar-2010
Many patients experience depression, social isolation and anxiety post stroke. These are associated with a poorer outcome. Ameliorating these problems may improve patient wellbeing.
- Structured telephone support or non‐invasive telemonitoring for patients with heart failure
Cochrane Systematic Reviews, 31-Oct-2015
Specialised disease management programmes for heart failure aim to improve care, clinical outcomes and/or reduce healthcare utilisation. Since the last version of this review in 2010, several new trials of structured telephone support and non-invasive hom
- Subcutaneous unfractionated heparin for the initial treatment of venous thromboembolism
Cochrane Systematic Reviews, 14-Feb-2017
Venous thromboembolism (VTE) is a prevalent and serious condition. Its medical treatment requires anticoagulation, usually with either unfractionated or low molecular weight heparin (LMWH). Administration of unfractionated heparin (UFH) is usually intrave
- Superoxide dismutase for preventing chronic lung disease in mechanically ventilated preterm infants
Cochrane Systematic Reviews, 22-Jan-2001
Free oxygen radicals have been implicated in the pathogenesis of chronic lung disease in preterm infants. Superoxide dismutase is a naturally occurring enzyme which provides a defence against such oxidant injury. Exogenously administered superoxide dismut
- Supervised exercise therapy versus home‐based exercise therapy versus walking advice for intermittent claudication
Cochrane Systematic Reviews, 6-Apr-2018
Although supervised exercise therapy (SET) provides significant symptomatic benefit for patients with intermittent claudication (IC), it remains an underutilized tool. Widespread implementation of SET is restricted by lack of facilities and funding. Struc
- Supportive devices for preventing and treating subluxation of the shoulder after stroke
Cochrane Systematic Reviews, 24-Jan-2005
Supportive devices such as slings, wheelchair attachments and orthoses have been used to treat subluxation of the shoulder after stroke.
- Surgery for deep venous insufficiency
Cochrane Systematic Reviews, 30-Sep-2021
Chronic deep venous insufficiency is caused by incompetent vein valves, blockage of large-calibre leg veins, or both; and causes a range of symptoms including recurrent ulcers, pain and swelling. Most surgeons accept that well-fitted graduated compression
- Surgery for primary supratentorial intracerebral haemorrhage
Cochrane Systematic Reviews, 12-Oct-2008
There is considerable international variation in the rate and indications of surgery for primary supratentorial intracerebral haematoma, reflecting the uncertainty about the effects of surgery. Recently, some large randomised trials have appeared in the l
- Surgery for small asymptomatic abdominal aortic aneurysms
Cochrane Systematic Reviews, 1-Jul-2020
An abdominal aortic aneurysm (AAA) is an abnormal ballooning of the major abdominal artery. Some AAAs present as emergencies and require surgery; others remain asymptomatic. Treatment of asymptomatic AAAs depends on many factors, but the size of the aneur
- Surgery for varicose veins: use of tourniquet
Cochrane Systematic Reviews, 10-Jun-2013
Varicose vein surgery is a common surgical procedure but there is no consensus regarding the best surgical technique. The use of tourniquets during varicose vein surgery has been advocated as a means of reducing the potential for blood loss during the ope
- Surgery versus sclerotherapy for the treatment of varicose veins
Cochrane Systematic Reviews, 18-Oct-2004
Varicose veins are a relatively common condition and account for around 54,000 in-patient hospital episodes per year. The two most common interventions for varicose veins are surgery and sclerotherapy. However, there is little comparative data regarding t
