Showing 561-580 of 753 for: Cochrane Systematic Reviews > Pharmacotherapeutics 
- Pharmacotherapy for Behcet's syndrome
Cochrane Systematic Reviews, 8-Nov-2008
Behcet's syndrome is a multisystemic disorder presenting with recurrent oral and genital ulcerations as well as ocular involvement. Treatment of Behcet's syndrome is symptomatic and empirical.
- Pharmacotherapy for dysthymia
Cochrane Systematic Reviews, 3-Nov-2008
Many drug treatments have been proposed for the treatment of dysthymia, but with so many potential comparisons it is not possible at the present time to determine which is the treatment of choice. There is a need to know whether the different classes of a
- Pharmacotherapy for hypertension in the elderly
Cochrane Systematic Reviews, 9-Nov-2010
Elevated blood pressure (known as hypertension) increases with age, and most rapidly over age 60. Systolic hypertension is more strongly associated with cardiovascular disease than diastolic hypertension, and occurs more commonly in older people. It is
- Pharmacotherapy for patellofemoral pain syndrome
Cochrane Systematic Reviews, 11-Aug-2008
Patellofemoral pain syndrome (PFPS) is common among adolescents and young adults. It is characterised by pain behind or around the patella and crepitations, provoked by ascending or descending stairs, squatting, prolonged sitting with flexed knees, runnin
- Pharmacotherapy for post traumatic stress disorder (PTSD)
Cochrane Systematic Reviews, 3-Nov-2008
Post traumatic stress disorder (PTSD) is a prevalent and disabling disorder. Evidence that PTSD is characterised by specific psychobiological dysfunctions has contributed to a growing interest in the use of medication in its treatment.
- Pharmacotherapy for social anxiety disorder (SAnD)
Cochrane Systematic Reviews, 19-Oct-2017
Recognition is growing that social anxiety disorder (SAnD) is a chronic and disabling disorder, and data from early trials demonstrate that medication may be effective in its treatment. This systematic review is an update of an earlier review of pharmacot
- Phytoestrogens for menopausal vasomotor symptoms
Cochrane Systematic Reviews, 6-Dec-2013
Vasomotor symptoms, such as hot flushes and night sweats, are very common during the menopausal transition. Hormone therapy has traditionally been used as a highly effective treatment, but concerns about increased risk of some chronic diseases have marked
- Pimozide for schizophrenia or related psychoses
Cochrane Systematic Reviews, 5-Nov-2013
Pimozide, formulated in the 1960s, continues to be marketed for the care of people with schizophrenia or related psychoses such as delusional disorder. It has been associated with cardiotoxicity and sudden unexplained death. Electrocardiogram monitoring i
- Plasma exchange for Guillain-Barré syndrome
Cochrane Systematic Reviews, 29-May-2012
Guillain-Barré syndrome is an acute paralysing disease caused by peripheral nerve inflammation. This is an update of a review first published in 2001 and last updated in 2008.
- Platelet glycoprotein IIb/IIIa blockers during percutaneous coronary intervention and as the initial medical treatment of non-ST segment elevation acute coronary syndromes
Cochrane Systematic Reviews, 7-Nov-2013
During percutaneous coronary intervention (PCI), and in non-ST segment elevation acute coronary syndromes (NSTEACS), the risk of acute vessel occlusion by thrombosis is high. Glycoprotein IIb/IIIa blockers strongly inhibit platelet aggregation and may pre
- Polyunsaturated fatty acid supplementation for schizophrenia
Cochrane Systematic Reviews, 4-Oct-2011
Limited evidence supports a hypothesis suggesting that the symptoms of schizophrenia may be the result of altered neuronal membrane structure and metabolism. The structure and metabolism is dependent on blood plasma levels of certain essential fatty acids
- Potassium containing toothpastes for dentine hypersensitivity
Cochrane Systematic Reviews, 6-Mar-2012
Dentine hypersensitivity may be defined as the pain arising from exposed dentine, typically in response to external stimuli, and which cannot be explained by any other form of dental disease. Many treatment regimens have been recommended over the years, a
- Pre-emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant recipients
Cochrane Systematic Reviews, 29-Jan-2013
Cytomegalovirus (CMV) is a significant cause of morbidity and mortality in solid organ transplant recipients. Pre-emptive treatment of patients with CMV viraemia using antiviral agents has been suggested as an alternative to routine prophylaxis to prevent
- Pregabalin add-on for drug-resistant partial epilepsy
Cochrane Systematic Reviews, 4-Mar-2014
Epilepsy is a common chronic neurological disease with an estimated prevalence of 1% in the UK. Approximately one third of these people continue to have seizures despite drug treatment. In order to try to improve outcomes a number of new antiepileptic dru
- Pregabalin for acute and chronic pain in adults
Cochrane Systematic Reviews, 23-Sep-2010
Antiepileptic drugs have been used in pain management since the 1960s. Pregabalin is a recently developed antiepileptic drug also used in management of chronic neuropathic pain conditions.
- Preoperative chemotherapy for resectable thoracic esophageal cancer
Cochrane Systematic Reviews, 13-May-2015
Surgery has been the treatment of choice for patients with localized esophageal cancer. Several studies have investigated whether preoperative chemotherapy followed by surgery leads to improvement in cure rates, but individual reports have provided confli
- Preoperative fasting for adults to prevent perioperative complications
Cochrane Systematic Reviews, 13-Apr-2010
Fasting before general anaesthesia aims to reduce the volume and acidity of stomach contents during surgery, thus reducing the risk of regurgitation/aspiration. Recent guidelines have recommended a shift in fasting policy from the standard 'nil by mouth f
- Pressurised metered dose inhalers versus all other hand-held inhaler devices to deliver beta-2 agonist bronchodilators for non-acute asthma
Cochrane Systematic Reviews, 25-May-2009
A number of different inhaler devices are available to deliver beta2-agonist bronchodilators in asthma. These include hydrofluoroalkane (HFA) or chlorofluorocarbon (CFC)-free propelled pressurised metered dose inhalers (pMDIs) and dry powder devices.
- Prevention of NSAID‐induced gastroduodenal ulcers
Cochrane Systematic Reviews, 21-Oct-2002
Non-steroidal anti-inflammatory drugs (NSAIDs) are important agents in the management of arthritic and inflammatory conditions, and are among the most frequently prescribed medications in North America and Europe. However, there is overwhelming evidence l
- Probiotics for induction of remission in ulcerative colitis
Cochrane Systematic Reviews, 26-May-2008
Ulcerative Colitis (UC) is an inflammatory condition affecting the colon with an incidence of approximately 10-20 per 100,000 per year. No existing intervention is effective in all patients with a proportion requiring colectomy. There are significant prop
