Showing 581-600 of 7110 for: Cochrane Systematic Reviews Back
- Anti-hypertensive drugs as disease-modifying agents for Parkinson's disease: evidence from observational studies and clinical trials
Cochrane Systematic Reviews, 20-Sep-2011
Current treatment for Parkinson's disease (PD) is focused on relieving symptoms, at present there is nothing that is widely accepted to halt or slow disease progression. Potential neuroprotective or disease modifying agents have been identified from precl
- Antihypertensive pharmacotherapy for prevention of sudden cardiac death in hypertensive individuals
Cochrane Systematic Reviews, 3-Mar-2016
High blood pressure is an important public health problem because of associated risks of stroke and cardiovascular events. Antihypertensive drugs are often used in the belief that lowering blood pressure will prevent cardiac events, including myocardial i
- Antihypertensive therapy for preventing cardiovascular complications in people with diabetes mellitus
Cochrane Systematic Reviews, 9-Nov-2008
Hypertension and diabetes mellitus are closely associated diseases which are both strongly related to the risk of cardiovascular disease.
- Antihypertensive treatment for kidney transplant recipients
Cochrane Systematic Reviews, 29-Nov-2009
In some nontransplant populations, effects of different antihypertensive drug classes vary. Relative effects in kidney transplant recipients are uncertain.
- Anti‐IgE therapy for allergic bronchopulmonary aspergillosis in people with cystic fibrosis
Cochrane Systematic Reviews, 22-Sep-2021
Cystic fibrosis is an autosomal recessive multisystem disorder with an approximate prevalence of 1 in 3500 live births. Allergic bronchopulmonary aspergillosis is a lung disease caused by aspergillus-induced hypersensitivity with a prevalence of 2% to 15%
- Anti-IL-12/23p40 antibodies for induction of remission in Crohn's disease
Cochrane Systematic Reviews, 13-May-2015
Ustekinumab (CNTO 1275) and briakinumab (ABT-874) are monoclonal antibodies that target the standard p40 subunit of the cytokines interleukin-12 and interleukin-23 (IL-12/23p40), which are involved in the pathogenesis of Crohn's disease.
- Anti‐IL‐5 therapies for asthma
Cochrane Systematic Reviews, 12-Jul-2022
This is the second update of previously published reviews in the Cochrane Library (2015, first update 2017). Interleukin-5 (IL-5) is the main cytokine involved in the proliferation, maturation, activation and survival of eosinophils, which cause airway in
- Anti-inflammatory drugs and analgesics for managing symptoms in people with cystic fibrosis-related arthritis
Cochrane Systematic Reviews, 21-Jan-2016
Arthritis remains a relatively infrequent complication of cystic fibrosis, but is a cause of significant morbidity when it does occur. Two distinct types of arthritis are described in cystic fibrosis: cystic fibrosis-related arthropathy (CFA) and hypertro
- Anti-inflammatory medications for obstructive sleep apnea in children
Cochrane Systematic Reviews, 6-Dec-2010
Obstructive sleep apnea (OSA) is characterized by partial or complete upper airway obstruction during sleep. Approximately 1% to 4% of children are affected by OSA, with adenotonsillar hypertrophy the most common underlying risk factor. Surgical removal o
- Anti-inflammatory treatment for carditis in acute rheumatic fever
Cochrane Systematic Reviews, 28-May-2015
Rheumatic heart disease remains an important cause of acquired heart disease in developing countries. Although prevention of rheumatic fever and management of recurrences have been well established, optimal management of active rheumatic carditis remains
- Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children
Cochrane Systematic Reviews, 8-Dec-2014
Anti-leukotrienes (5-lipoxygenase inhibitors and leukotriene receptors antagonists) serve as alternative monotherapy to inhaled corticosteroids (ICS) in the management of recurrent and/or chronic asthma in adults and children.
- Antimalarials for treating rheumatoid arthritis
Cochrane Systematic Reviews, 24-May-2010
Antimalarials have been used for the treatment of rheumatoid arthritis (RA) for several decades. Recently several trials have been published with larger sample sizes, and better design than previous studies. These newer trials have evaluated the efficacy
- Antimetabolites in cataract surgery to prevent failure of a previous trabeculectomy
Cochrane Systematic Reviews, 20-Jul-2014
Patients having cataract surgery have often earlier undergone a trabeculectomy for glaucoma. However, cataract surgery may be associated with failure of the previous glaucoma surgery and antimetabolites may be used with cataract surgery to prevent such fa
- Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients
Cochrane Systematic Reviews, 17-Mar-2010
Peritoneal dialysis (PD) is used as substitutive treatment of renal function in a large proportion (15-50%) of the end-stage kidney disease (ESRD) population. The major limitation is peritonitis which leads to technique failure, hospitalisation and increa
- Antimicrobial agents for preventing urinary tract infections in adults undergoing cystoscopy
Cochrane Systematic Reviews, 21-Feb-2019
Cystoscopy is commonly performed for diagnostic purposes to inspect the interior lining of the bladder. One disadvantage of cystoscopy is the risk of symptomatic urinary tract infection (UTI) due to pre-existing colonization or by introduction of bacteria
- Antimicrobial agents for treating uncomplicated urinary tract infection in women
Cochrane Systematic Reviews, 8-Nov-2010
Acute uncomplicated lower urinary tract infection (UTI) is one of the most common problems for which young women seek medical attention.
- Antimicrobial dressings for the prevention of catheter-related infections in newborn infants with central venous catheters
Cochrane Systematic Reviews, 21-Mar-2016
Central venous catheters (CVCs) provide secured venous access in neonates. Antimicrobial dressings applied over the CVC sites have been proposed to reduce catheter-related blood stream infection (CRBSI) by decreasing colonisation. However, there may be co
- Antimicrobial drugs for treating cholera
Cochrane Systematic Reviews, 12-Jun-2014
Cholera is an acute watery diarrhoea caused by infection with the bacterium Vibrio cholerae, which if severe can cause rapid dehydration and death. Effective management requires early diagnosis and rehydration using oral rehydration salts or intravenous f
- Antimicrobial drugs for treating methicillin-resistant Staphylococcus aureus colonization
Cochrane Systematic Reviews, 17-Jun-2008
Eradication strategies for methicillin-resistant Staphylococcus aureus (MRSA) are variable. We sought to summarize the evidence for use of antimicrobial agents to eradicate MRSA.
- Antimicrobial prophylaxis for colorectal surgery
Cochrane Systematic Reviews, 27-Aug-2015
Research shows that administration of prophylactic antibiotics before colorectal surgery prevents postoperative surgical wound infection. The best antibiotic choice, timing of administration and route of administration remain undetermined.