- Perioperative ketamine for acute postoperative pain
Cochrane Systematic Reviews, 2-Jul-2015
Postoperative pain management is often limited by adverse effects such as nausea and vomiting. Adjuvant treatment with an inexpensive opioid-sparing drug such as ketamine may be of value in giving better analgesia with fewer adverse effects. - Perioperative local anaesthesia for reducing pain following septal surgery
Cochrane Systematic Reviews, 13-Aug-2018
Septal surgery is a well-established procedure used to treat nasal obstruction due to deviation of the nasal septum, which is carried out under local or general anaesthesia. Local anaesthesia is used for postoperative pain control, but its effectiveness a - Perioperative local anaesthesia for reducing pain following tonsillectomy
Cochrane Systematic Reviews, 25-Oct-1999
Pain relief after tonsillectomy is an important part of post-operative management. Sometimes local anaesthetics are administed to the tonsillar region, but their effectiveness in relieving pain has not been formally assessed. - Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty
Cochrane Systematic Reviews, 23-Feb-2017
Glaucoma is the international leading cause of irreversible blindness. Intraocular pressure (IOP) is the only currently known modifiable risk factor; it can be reduced by medications, incisional surgery, or laser trabeculoplasty (LTP). LTP reduces IOP by - Perioperative nutrition for the treatment of bladder cancer by radical cystectomy
Cochrane Systematic Reviews, 20-May-2019
Radical cystectomy (RC) is the primary surgical treatment for muscle-invasive urothelial carcinoma of the bladder. This major operation is typically associated with an extended hospital stay, a prolonged recovery period and potentially major complications - Perioperative nutrition interventions for women with ovarian cancer
Cochrane Systematic Reviews, 11-Sep-2013
Women with ovarian cancer have been shown to be at significant risk of malnutrition with incidence rates described as being between 28% to 67%. Nutrition interventions may improve clinical outcomes positively, nutritional status or quality of life measure - Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures
Cochrane Systematic Reviews, 13-May-2022
Developments in ultrasound assessment of pregnancy has resulted in the increasing diagnosis of antenatal fetal issues. Many structural fetal conditions as well as complications associated with multiple pregnancies have the potential for in-utero treatment - Perioperative restrictive versus goal‐directed fluid therapy for adults undergoing major non‐cardiac surgery
Cochrane Systematic Reviews, 12-Dec-2019
Perioperative fluid management is a crucial element of perioperative care and has been studied extensively recently; however, 'the right amount' remains uncertain. One concept in perioperative fluid handling is goal-directed fluid therapy (GDFT), wherein - Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery
Cochrane Systematic Reviews, 3-Jul-2013
Patients undergoing vascular surgery are a high-risk population with widespread atherosclerosis, an adverse cardiovascular risk profile and often multiple co-morbidities. Postoperative cardiovascular complications, including myocardial infarct (MI), are c - Perioperative systemic nonsteroidal anti‐inflammatory drugs (NSAIDs) in women undergoing breast surgery
Cochrane Systematic Reviews, 9-Nov-2021
Breast surgery encompasses oncologic, reconstructive, and cosmetic procedures. With the recent focus on the over-prescribing of opioids in the literature, it is important to assess the effectiveness and safety of non-opioid pain medication regimens includ - Perioperative transversus abdominis plane (TAP) blocks for analgesia after abdominal surgery
Cochrane Systematic Reviews, 9-Apr-2020
- Peripheral iridotomy for pigmentary glaucoma
Cochrane Systematic Reviews, 12-Feb-2016
Glaucoma is a chronic optic neuropathy characterized by retinal ganglion cell death resulting in damage to the optic nerve head and the retinal nerve fiber layer. Pigment dispersion syndrome is characterized by a structural disturbance in the iris pigment - Peripheral nerve blocks for hip fractures in adults
Cochrane Systematic Reviews, 25-Nov-2020
This review was published originally in 1999 and was updated in 2001, 2002, 2009, 2017, and 2020. Updating was deemed necessary due to the high incidence of hip fractures, the large number of official societies providing recommendations on this condition, - Peripheral nerve blocks for postoperative pain after major knee surgery
Cochrane Systematic Reviews, 6-Aug-2019
Major knee surgery is a common operative procedure to help people with end-stage knee disease or trauma to regain mobility and have improved quality of life. Poorly controlled pain immediately after surgery is still a key issue for this procedure. Periphe - Peripheral retinal ablation for threshold retinopathy of prematurity in preterm infants
Cochrane Systematic Reviews, 26-Jul-1999
This section is under preparation and will be included in the next issue. - Peritoneal closure versus no peritoneal closure for patients undergoing non‐obstetric abdominal operations
Cochrane Systematic Reviews, 4-Jul-2013
There is no consensus regarding whether the peritoneum should be closed or left open during non-obstetric operations involving laparotomy. Neither is there consensus about the method of closure of the peritoneum (continuous suture versus interrupted sutur - Peritoneal dialysis for acute kidney injury
Cochrane Systematic Reviews, 4-Dec-2017
Peritoneal dialysis (PD) has been suggested as an effective and safe dialysis modality in patients with acute kidney injury (AKI). However, whether PD is superior to extracorporeal therapy (e.g. haemodialysis) in terms of improving survival, recovery of k - Peritoneal drainage versus laparotomy as initial surgical treatment for perforated necrotizing enterocolitis or spontaneous intestinal perforation in preterm low birth weight infants
Cochrane Systematic Reviews, 5-May-2011
Standard surgical management of infants with perforated necrotizing enterocolitis (NEC) or spontaneous intestinal perforation (SIP) is laparotomy with the resection of the necrotic or perforated segments of the intestine. Peritoneal drainage is an alterna - Permissive hypercapnia for the prevention of morbidity and mortality in mechanically ventilated newborn infants
Cochrane Systematic Reviews, 23-Apr-2001
Experimental animal data and uncontrolled, observational studies in human infants have suggested that hyperventilation and hypocapnia may be associated with increased pulmonary and neurodevelopmental morbidity. Protective ventilatory strategies allowing h - Permissive hypoxaemia versus normoxaemia for mechanically ventilated critically ill patients
Cochrane Systematic Reviews, 20-Dec-2018
Permissive hypoxaemia describes a concept in which a lower level of arterial oxygenation (PaO2) than usual is accepted to avoid the detrimental effects of high fractional inspired oxygen and invasive mechanical ventilation. Currently however, no specific
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