Showing 621-640 of 746 for: Cochrane Systematic Reviews > Pharmacotherapeutics
- Routine anticonvulsants for treating cerebral malaria
Cochrane Systematic Reviews, 22-Apr-2002
Cerebral malaria is a common complication of Plasmodium falciparum infection, and kills over a million people every year. People with cerebral malaria become unconscious, and often have protracted convulsions. It is unclear whether giving anticonvulsant d
- Routine versus selective antifungal administration for control of fungal infections in patients with cancer
Cochrane Systematic Reviews, 4-Sep-2014
Systemic fungal infection is considered to be an important cause of morbidity and mortality in cancer patients, particularly those with neutropenia. Antifungal drugs are often given prophylactically, or empirically to patients with persistent fever.
- Safety of topical corticosteroids in pregnancy
Cochrane Systematic Reviews, 26-Oct-2015
Topical corticosteroids are the most frequently prescribed dermatological treatment and are often used by pregnant women with skin conditions. However, little is known about their safety in pregnancy.
- Second‐line chemotherapy for non‐small cell lung cancer
Cochrane Systematic Reviews, 22-Apr-2002
The role of second-line chemotherapy for the treatment of patients with non-small cell lung cancer (NSCLC) who have relapsed or failed to respond to first-line treatment was unclear.
- Sedatives for opioid withdrawal in newborn infants
Cochrane Systematic Reviews, 18-May-2021
Neonatal abstinence syndrome (NAS) due to opioid withdrawal may result in disruption of the mother–infant relationship, sleep–wake abnormalities, feeding difficulties, weight loss, seizures and neurodevelopmental problems.
- Selective estrogen receptor modulators (SERMs) for uterine leiomyomas
Cochrane Systematic Reviews, 17-Oct-2012
Uterine fibroids are benign tumours that arise from individual smooth muscle cells of the uterus. Selective estrogen receptor modulators (SERMs) are estrogen receptor (ER) ligands that act as estrogens in some tissues while blocking estrogen activity in o
- Selective serotonin reuptake inhibitors (SSRIs) and serotonin‐norepinephrine reuptake inhibitors (SNRIs) for the prevention of migraine in adults
Cochrane Systematic Reviews, 1-Apr-2015
This is an updated version of the original Cochrane review published in 2005 on selective serotonin reuptake inhibitors (SSRIs) for preventing migraine and tension-type headache. The original review has been split in two parts and this review now only reg
- Selective serotonin re‐uptake inhibitors (SSRIs) versus placebo for obsessive compulsive disorder (OCD)
Cochrane Systematic Reviews, 23-Jan-2008
Obsessive compulsive disorder is a common and disabling disorder. A significant proportion of patients manifest a chronic course. Individual randomised controlled trials (RCTs) have shown that selective serotonin re-uptake inhibitors (SSRIs) are effective
- Selective serotonin reuptake inhibitors for premenstrual syndrome
Cochrane Systematic Reviews, 7-Jun-2013
Premenstrual syndrome (PMS) is a common cause of physical, psychological and social problems in women of reproductive age. The key characteristic of PMS is the timing of symptoms, which occur only during the two weeks leading up to menstruation (the lutea
- Self‐management interventions for people with chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 10-Jan-2022
Self-management interventions help people with chronic obstructive pulmonary disease (COPD) to acquire and practise the skills they need to carry out disease-specific medical regimens, guide changes in health behaviour and provide emotional support to ena
- Self‐monitoring and self‐management of oral anticoagulation
Cochrane Systematic Reviews, 5-Jul-2016
The introduction of point-of-care devices for the management of patients on oral anticoagulation allows self-testing by the patient at home. Patients who self-test can either adjust their medication according to a pre-determined dose-INR (international no
- Sequential combination of glucocorticosteroids and alfa interferon versus alfa interferon alone for HBeAg‐positive chronic hepatitis B
Cochrane Systematic Reviews, 20-Jul-2005
Chronic hepatitis B has serious effects on morbidity and mortality. Alfa interferon has been shown to increase the rates of HBeAg-clearance as well as seroconversion to anti-HBe, but response rates are unsatisfactory. Glucocorticosteroid pretreatment may
- Sertindole for schizophrenia
Cochrane Systematic Reviews, 20-Jul-2005
Sertindole is an atypical antipsychotic, which is thought to give a lower incidence of extrapyramidal side effects at clinically effective doses than typical antipsychotic drugs. In December 1998, Lundbeck Ltd., the manufacturers of sertindole, voluntaril
- Short acting beta2-agonists for bronchiectasis
Cochrane Systematic Reviews, 13-May-2008
Bronchiectasis is a condition characterized by an abnormal and irreversible dilatation of the sub segmental airways and it may be caused by a variety of disease processes. Currently medical treatment includes physiotherapy, antibiotics and occasionally mu
- Short acting beta2‐agonists for recurrent wheeze in children under two years of age
Cochrane Systematic Reviews, 22-Apr-2002
Wheeze is a common symptom in infancy and is a common cause for both primary care consultations and hospital admission. Beta2-adrenoceptor agonists (b2-agonists) are the most frequently used as bronchodilator but their efficacy is questionable.
- Short‐acting beta2‐agonists for stable chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 22-Jul-2002
Chronic Obstructive Pulmonary Disease (COPD) is a chronic condition characterised by progressive airflow limitation that is at most partially reversible. Despite the lack of reversibility patients often report symptomatic improvement with short-acting bet
- Short‐course antibiotics for acute otitis media
Cochrane Systematic Reviews, 8-Sep-2010
Acute otitis media (AOM) is a common illness during childhood, for which antibiotics are frequently prescribed.
- Short‐course versus long‐course antibiotic therapy for non‐severe community‐acquired pneumonia in children aged 2 months to 59 months
Cochrane Systematic Reviews, 23-Apr-2008
Pneumonia is the leading cause of mortality in children under five years of age. Treatment of pneumonia requires an effective antibiotic used in adequate doses for an appropriate duration. Recommended duration of treatment ranges between 7 and 14 days, bu
- Short‐term low‐dose corticosteroids vs placebo and nonsteroidal antiinflammatory drugs in rheumatoid arthritis
Cochrane Systematic Reviews, 24-Jan-2005
The effect of low dose corticosteroids, equivalent to 15 mg prednisolone daily or less, in patients with rheumatoid arthritis has been questioned. We reviewed the trials that compared corticosteroids with placebo or non-steroidal, anti-inflammatory drugs.
- Short‐term treatment with proton pump inhibitors, H2‐receptor antagonists and prokinetics for gastro‐oesophageal reflux disease‐like symptoms and endoscopy negative reflux disease
Cochrane Systematic Reviews, 31-May-2013
Approximately 25% of adults regularly experience heartburn, a symptom of gastro-oesophageal reflux disease (GORD). Most patients are treated empirically (without specific diagnostic evaluation e.g. endoscopy. Among patients who have an upper endoscopy, fi