Showing 6581-6600 of 7110 for: Cochrane Systematic Reviews Back
- Topical corticosteroids for dry eye
Cochrane Systematic Reviews, 21-Oct-2022
Dry eye disease (DED), arising from various etiologic factors, leads to tear film instability, ocular surface damage, and neurosensory changes. DED causes symptoms such as ocular dryness, burning, itching, pain, and visual impairment. Given their well-est
- Topical corticosteroids for treating phimosis in boys
Cochrane Systematic Reviews, 29-Aug-2014
Until recently, phimosis has been treated surgically by circumcision or prepuceplasty; however, recent reports of non-invasive treatment using topical corticosteroids applied for four to eight weeks have been favourable. The efficacy and safety of topical
- Topical cyclosporine for atopic keratoconjunctivitis
Cochrane Systematic Reviews, 19-Jul-2012
Atopic keratoconjunctivitis (AKC) is a chronic ocular surface non-infectious inflammatory condition that atopic dermatitis patients may suffer at any time point in the course of their dermatologic disease and is independent of its degree of severity. AKC
- Topical cystic fibrosis transmembrane conductance regulator gene replacement for cystic fibrosis-related lung disease
Cochrane Systematic Reviews, 21-Nov-2013
Cystic fibrosis is caused by a defective gene encoding a protein called the cystic fibrosis transmembrane conductance regulator (CFTR), and is characterised by chronic lung infection resulting in inflammation and progressive lung damage that results in a
- Topical emollient for preventing infection in preterm infants
Cochrane Systematic Reviews, 7-May-2021
Breakdown of the developmentally immature epidermal barrier may permit entry for micro-organisms leading to invasive infection in preterm infants. Topical emollients may improve skin integrity and barrier function and thereby prevent invasive infection, a
- Topical fluoride (toothpastes, mouthrinses, gels or varnishes) for preventing dental caries in children and adolescents
Cochrane Systematic Reviews, 28-Aug-2008
Topical fluoride therapy (TFT) in the form of varnish, gel, mouthrinse or toothpaste has been used extensively as a caries-preventive intervention for over 3 decades.
- Topical fluoride as a cause of dental fluorosis in children
Cochrane Systematic Reviews, 11-May-2010
For many years, topical use of fluorides has gained greater popularity than systemic use of fluorides. A possible adverse effect associated with the use of topical fluoride is the development of dental fluorosis due to the ingestion of excessive fluoride
- Topical glyceryl trinitrate for rotator cuff disease
Cochrane Systematic Reviews, 12-May-2009
Rotator cuff disease is a common cause of shoulder pain. Topical glyceryl trinitrate is a possible new treatment.
- Topical herbal therapies for treating osteoarthritis
Cochrane Systematic Reviews, 28-May-2013
Before extraction and synthetic chemistry were invented, musculoskeletal complaints were treated with preparations from medicinal plants. They were either administered orally or topically. In contrast to the oral medicinal plant products, topicals act in
- Topical interventions for genital lichen sclerosus
Cochrane Systematic Reviews, 25-Oct-2011
Lichen sclerosus is a chronic, inflammatory skin condition that most commonly occurs in adult women, although it may also be seen in men and children. It primarily affects the genital area and around the anus, where it causes persistent itching and sorene
- Topical lidocaine for neuropathic pain in adults
Cochrane Systematic Reviews, 23-Jul-2014
Lidocaine is a local anaesthetic that is sometimes used on the skin to treat neuropathic pain.
- Topical lidocaine for the treatment of postherpetic neuralgia
Cochrane Systematic Reviews, 28-Oct-2013
This is an update of the original Cochrane review published in Issue 2, 2007. The cause of postherpetic neuralgia is damage to peripheral neurons, dorsal root ganglia, and the dorsal horn of the spinal cord, secondary to herpes zoster infection (shingles)
- Topical microbicides for prevention of sexually transmitted infections
Cochrane Systematic Reviews, 8-May-2012
Two decades of research on topical microbicides for prevention of sexually transmitted infections (STIs) have had limited success. However, new microbicide randomised controlled trial (RCT) data have recently been published; but these have not yet been th
- Topical nasal steroids for intermittent and persistent allergic rhinitis in children
Cochrane Systematic Reviews, 10-Nov-2008
Allergic rhinitis is a very common chronic illness affecting 10% to 40% of children worldwide. There has been a significant increase in prevalence among children over the last two decades and this increase has been accompanied by a parallel increase in co
- Topical nasal steroids for treating nasal polyposis in people with cystic fibrosis
Cochrane Systematic Reviews, 10-Jun-2015
Nasal polyps frequently occur in people with cystic fibrosis. Sinus infections have been shown to be a factor in the development of serious chest complications in these people. Nasal polyps have been linked to a higher risk of lower respiratory tract infe
- Topical negative pressure for treating chronic wounds
Cochrane Systematic Reviews, 9-Jun-2015
Chronic wounds mainly affect the elderly and those with multiple health problems. Despite the use of modern dressings, some of these wounds take a long time to heal, fail to heal, or recur, causing significant pain and discomfort to the person and cost to
- Topical non-steroidal anti-inflammatory agents for diabetic cystoid macular oedema
Cochrane Systematic Reviews, 12-Feb-2015
Diabetic cystoid macular oedema (CMO) is a condition which involves fluid accumulation in the inner portion of the retina. It often follows changes in retinal blood vessels which enhance the fluid to come out of vessels. Although it may be asymptomatic, s
- Topical NSAIDs for acute musculoskeletal pain in adults
Cochrane Systematic Reviews, 4-Feb-2016
Use of topical NSAIDs to treat acute musculoskeletal conditions has become widely accepted because they can provide pain relief without associated systemic adverse events. This review is an update of 'Topical NSAIDs for acute pain in adults' originally pu
- Topical NSAIDs for chronic musculoskeletal pain in adults
Cochrane Systematic Reviews, 13-Aug-2012
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly taken orally, but they are also available in topical preparations to be applied to or rubbed onto the skin of a painful joint, typically one affected by arthritis, with the aim of relieving pain
- Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis
Cochrane Systematic Reviews, 3-Mar-2022
Viruses cause about 80% of all cases of acute conjunctivitis. Human adenoviruses are believed to account for 65% to 90% of cases of viral conjunctivitis, or 20% to 75% of all causes of infectious keratoconjunctivitis worldwide. Epidemic keratoconjunctivit
