- Topical pimecrolimus for eczema
Cochrane Systematic Reviews, 22-Mar-2009
Pimecrolimus was developed as an alternative to topical corticosteroids for treating eczema (atopic dermatitis) but its efficacy and safety compared with existing treatments remains unclear. - Topical preparations for preventing stretch marks in pregnancy
Cochrane Systematic Reviews, 5-Oct-2012
Striae gravidarum (stretch marks developing during pregnancy) occur in 50% to 90% of women. They appear as red or purple lines or streaks that fade slowly to leave pale lines or marks on the skin. The abdomen, breasts and thighs are commonly affected. The - Topical silver for preventing wound infection
Cochrane Systematic Reviews, 15-Feb-2010
Silver-containing treatments are popular and used in wound treatments to combat a broad spectrum of pathogens, but evidence of their effectiveness in preventing wound infection or promoting healing is lacking. - Topical silver for treating infected wounds
Cochrane Systematic Reviews, 6-Sep-2010
Topical silver treatments and silver dressings are increasingly used for the local treatment of contaminated or infected wounds, however, there is a lack of clarity regarding the evidence for their effectiveness. - Topical steroid for chronic rhinosinusitis without polyps
Cochrane Systematic Reviews, 4-Jul-2011
Topical corticosteroid is used as part of a comprehensive medical treatment for chronic rhinosinusitis (CRS) without polyps. Nevertheless, there is insufficient evidence to show a clear overall benefit. Trials studying the efficacy of topical corticostero - Topical steroids for nasal polyps
Cochrane Systematic Reviews, 5-Nov-2012
Chronic rhinosinusitis with nasal polyps (CRSwNP) represents inflammatory changes throughout the nose and sinuses from a group of disorders which all lead to swelling and overgrowth of the nasal mucosa. Topical corticosteroids have been the most widely us - Topical tacrolimus for atopic dermatitis
Cochrane Systematic Reviews, 21-Jul-2015
Atopic dermatitis (AD) (or atopic eczema) is a chronic inflammatory skin condition that affects children and adults and has an important impact on quality of life. Topical corticosteroids (TCS) are the first-line therapy for this condition; however, they - Topical treatment for facial burns
Cochrane Systematic Reviews, 5-Dec-2012
Burn injuries are an important health problem. They occur frequently in the head and neck region - the area central to a person's identity, that provides our most expressive means of communication. Topical interventions are currently the cornerstone of tr - Topical treatment for vaginal candidiasis (thrush) in pregnancy
Cochrane Systematic Reviews, 30-Jan-2013
Vaginal candidiasis (moniliasis or thrush) is a common and frequently distressing infection for many women. It is even more common in pregnancy. There is no evidence that thrush in pregnancy is harmful to the baby. - Topical treatments for chronic plaque psoriasis
Cochrane Systematic Reviews, 9-Dec-2015
Chronic plaque psoriasis is the most common type of psoriasis, and it is characterised by redness, thickness, and scaling. First-line management of chronic plaque psoriasis is with topical treatments, including vitamin D analogues, topical corticosteroids - Topical treatments for cutaneous warts
Cochrane Systematic Reviews, 4-Feb-2014
Viral warts are a common skin condition, which can range in severity from a minor nuisance that resolve spontaneously to a troublesome, chronic condition. Many different topical treatments are available. - Topical treatments for fungal infections of the skin and nails of the foot.
Cochrane Systematic Reviews, 1-Mar-2016
Fungal infections of the feet normally occur in the outermost layer of the skin (epidermis). The skin between the toes is a frequent site of infection which can cause pain and itchiness. Fungal infections of the nail (onychomycosis) can affect the entire - Topical treatments for HIV-related oral ulcers
Cochrane Systematic Reviews, 5-Dec-2011
In HIV-infected adults, oral ulcers occur more frequently, last longer and produce more painful symptoms than in immunocompetent people. Oral aphthous ulcers observed during the course of HIV infection may be severe and can result in significant morbidity - Topical treatments for scalp psoriasis
Cochrane Systematic Reviews, 24-Feb-2016
People with chronic plaque psoriasis often have lesions on the scalp. Hair makes the scalp difficult to treat and the adjacent facial skin is particularly sensitive to topical treatments. - Topical umbilical cord care at birth
Cochrane Systematic Reviews, 30-Jan-2013
Umbilical cord infection caused many neonatal deaths before aseptic techniques were used. - Topical Vitamin A, or its derivatives, for treating and preventing napkin dermatitis in infants
Cochrane Systematic Reviews, 22-Mar-2009
Napkin dermatitis (nappy or diaper rash) is a non-specific term used to describe inflammatory eruptions (rashes) in the napkin area. Most infants develop napkin dermatitis at least once during their infancy. Topical vitamin A has been suggested as a treat - Topically applied anaesthetics for treating perineal pain after childbirth
Cochrane Systematic Reviews, 29-Oct-2008
Perineal trauma is a major problem affecting millions of women around the world each year. The degree of perineal pain and discomfort associated with perineal trauma is often underestimated. Pain often interferes with basic daily activities for the woman - Topiramate add-on for drug-resistant partial epilepsy
Cochrane Systematic Reviews, 14-Feb-2014
The majority of people with epilepsy have a good prognosis and their seizures are controlled by a single antiepileptic drug. However, up to 20% of patients from population-based studies and up to 30% from clinical series (not population-based) develop dru - Topiramate for acute affective episodes in bipolar disorder
Cochrane Systematic Reviews, 5-Nov-2008
Bipolar disorder is a common recurrent illness with high levels of chronicity. Treatment resistance persists despite the use of established medications, such as lithium and valproate. New medications are required for the treatment of refractory cases. Ret - Topiramate for neuropathic pain and fibromyalgia in adults
Cochrane Systematic Reviews, 30-Aug-2013
Topiramate is an antiepileptic drug with multiple possible mechanisms of action. Antiepileptic drugs are widely used to treat chronic neuropathic pain (pain due to nerve damage) and fibromyalgia, and many guidelines recommend them.
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