Showing 661-680 of 746 for: Cochrane Systematic Reviews > Pharmacotherapeutics 
- Single dose oral tiaprofenic acid for acute postoperative pain in adults
Cochrane Systematic Reviews, 29-May-2019
Tiaprofenic acid is a a non-steroidal anti-inflammatory drug (NSAID). It is widely available around the world, with indications for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, periarticular disorders, and strains and sprains. This review
- Single versus combination intravenous anti‐pseudomonal antibiotic therapy for people with cystic fibrosis
Cochrane Systematic Reviews, 23-Jun-2021
The choice of antibiotic, and the use of single or combined therapy are controversial areas in the treatment of respiratory infection due to Pseudomonas aeruginosa in cystic fibrosis (CF). Advantages of combination therapy include wider range of modes of
- Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne
Cochrane Systematic Reviews, 15-Mar-2011
Hirsutism is the presence of excessive hair growth in women and is an important cosmetic condition often resulting in severe distress. The most common cause is by increased production of male sex hormones (androgens). It is also affected by increased sens
- Statins and fibrates for preventing melanoma
Cochrane Systematic Reviews, 19-Oct-2005
Effective treatment for advanced melanoma is lacking. While no drug therapy currently exists for prevention of melanoma, in vitro, case-control, and animal model evidence suggest that lipid-lowering medications, commonly taken for high cholesterol, might
- Statins for the prevention of dementia
Cochrane Systematic Reviews, 4-Jan-2016
This is an update of a Cochrane review first published in 2001 and then updated in 2009. Vascular risk factors including high cholesterol levels increase the risk of dementia due to Alzheimer's disease and of vascular dementia. Some observational studies
- Steroid hormones for contraception in men
Cochrane Systematic Reviews, 14-Mar-2012
Male hormonal contraception has been an elusive goal. Administration of sex steroids to men can shut off sperm production through effects on the pituitary and hypothalamus. However, this approach also decreases production of testosterone, so 'add-back' th
- Steroid sex hormones for lower limb atherosclerosis
Cochrane Systematic Reviews, 17-Oct-2012
There is accumulating evidence that steroid sex hormones have a beneficial effect on a number of risk factors for peripheral arterial disease.
- Steroids for acute spinal cord injury
Cochrane Systematic Reviews, 18-Jan-2012
Acute spinal cord injury is a devastating condition typically affecting young people, mostly males. Steroid treatment in the early hours after the injury is aimed at reducing the extent of permanent paralysis during the rest of the patient's life.
- Steroids for idiopathic sudden sensorineural hearing loss
Cochrane Systematic Reviews, 2-Jul-2013
This is an update of a Cochrane review first published in The Cochrane Library in Issue 1, 2006 and previously updated in 2009.
- Steroids for improving recovery following tonsillectomy in children
Cochrane Systematic Reviews, 10-Aug-2011
This is an update of a Cochrane Review first published in The Cochrane Library in Issue 1, 2003.
- Steroids for symptom control in infectious mononucleosis
Cochrane Systematic Reviews, 8-Nov-2015
Infectious mononucleosis, also known as glandular fever or the kissing disease, is a benign lymphoproliferative disorder. It is a viral infection caused by the Epstein-Barr virus (EBV), a ubiquitous herpes virus that is found in all human societies and cu
- Steroids for traumatic optic neuropathy
Cochrane Systematic Reviews, 17-Jun-2013
Traumatic optic neuropathy (TON) is an important cause of severe visual loss following blunt or penetrating head trauma. Following the initial injury, optic nerve swelling within the optic nerve canal can result in secondary retinal ganglion cell loss. Op
- Steroids for treating cerebral malaria
Cochrane Systematic Reviews, 26-Jul-1999
Cerebral malaria is associated with swelling of the brain. Corticosteroid drugs could reduce the harmful effects of this swelling, but they could also suppress host immunity to infection.
- Steroids, radiotherapy, chemotherapy and stents for superior vena caval obstruction in carcinoma of the bronchus
Cochrane Systematic Reviews, 9-Mar-2015
Superior vena caval obstruction (SVCO) is an uncommon manifestation of carcinoma of the bronchus characterised by neck swelling and distended veins over the chest. Treatment options include radiotherapy, chemotherapy, steroids and insertion of an expandab
- Stimulant laxatives for constipation and soiling in children
Cochrane Systematic Reviews, 23-Jul-2001
Constipation is extremely common in childhood and may lead to overflow soiling/encopresis. Standard treatment of the more severe case is to empty the bowels of impacted faeces by the use of oral or rectal laxatives and then maintain regular bowel movement
- Strategies for managing sexual dysfunction induced by antidepressant medication
Cochrane Systematic Reviews, 16-Apr-2013
Sexual dysfunction (including altered sexual desire, orgasmic and ejaculatory dysfunction, erectile and other problems) is a relatively common side effect of antidepressant medication. These sexual side effects may compromise a person's lifestyle and resu
- Sulpiride for schizophrenia
Cochrane Systematic Reviews, 17-Oct-2012
The antipsychotic drug sulpiride was formulated over 20 years ago and was marked as having a low incidence of adverse effects and an effect on the negative symptoms of schizophrenia. This relatively inexpensive antipsychotic drug has a similar neuropharma
- Supportive care for patients with gastrointestinal cancer
Cochrane Systematic Reviews, 19-Jul-2004
This review is an update of a previously published update review in The Cochrane Database of Systematic Reviews (Issue 4, 2006) on this topic. No new studies have been identified from the update search and the conclusions are not altered. Supportive care
- Surgery versus primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus)
Cochrane Systematic Reviews, 18-May-2014
Several studies have evaluated the clinical effectiveness of endocrine therapy alone in women aged 70 years or over with operable breast cancer and who are fit for surgery.
- Surgery versus thrombolysis for initial management of acute limb ischaemia
Cochrane Systematic Reviews, 10-Aug-2018
Both peripheral arterial thrombolysis and surgery can be used in the management of peripheral arterial ischaemia. Much is known about the indications, risks, and benefits of thrombolysis. However, whether thrombolysis works better than surgery for initial
