Showing 661-680 of 753 for: Cochrane Systematic Reviews > Pharmacotherapeutics
- Single dose oral meloxicam for acute postoperative pain in adults
Cochrane Systematic Reviews, 14-Sep-2011
Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) used mainly in treating pain associated with arthritis. The usual oral dose for osteoarthritis is 15 mg daily, but lower doses of 7.5 mg are advised in older patients. This review sought to evalu
- Single dose oral nabumetone for acute postoperative pain in adults
Cochrane Systematic Reviews, 9-Nov-2010
Nabumetone is a non-steroidal anti-inflammatory drug (NSAID) used mainly in treating pain associated with arthritis. The usual oral dose for osteoarthritis is 1000 mg daily, and higher doses are not advised in older patients. There are no known systematic
- Single dose oral oxycodone and oxycodone plus paracetamol (acetaminophen) for acute postoperative pain in adults
Cochrane Systematic Reviews, 23-Sep-2010
Oxycodone is a strong opioid agonist used to treat severe pain. It is commonly combined with milder analgesics such as paracetamol. This review updates a previous review that concluded, based on limited data, that all doses of oxycodone exceeding 5 mg, wi
- Single dose oral piroxicam for acute postoperative pain
Cochrane Systematic Reviews, 3-Jul-2010
This is an updated version of the original Cochrane review published in Issue 2, 2000. Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties, and is used mainly for treating rheumatic disorders. Some drugs have been directl
- Single dose oral rofecoxib for acute postoperative pain in adults
Cochrane Systematic Reviews, 9-Nov-2010
Editor's note: The anti-inflammatory drug rofecoxib (Vioxx) was withdrawn from the market at the end of September 2004 after it was shown that long-term use (greater than 18 months) could increase the risk of heart attack and stroke in a study of secondar
- Single dose oral sulindac for acute postoperative pain in adults
Cochrane Systematic Reviews, 9-Nov-2010
Sulindac is a non-steroidal anti-inflammatory drug (NSAID) licensed for use in rheumatic disease and other musculoskeletal disorders in the UK, and widely available in other countries worldwide. This review sought to evaluate the efficacy and safety of or
- Single dose oral tenoxicam for acute postoperative pain in adults
Cochrane Systematic Reviews, 9-Nov-2010
Tenoxicam is a non-steroidal anti-inflammatory drug (NSAID) licensed for use in rheumatic disease and other musculoskeletal disorders in the UK, and is widely available in other countries worldwide. This review sought to evaluate the efficacy and safety o
- Single dose oral tiaprofenic acid for acute postoperative pain in adults
Cochrane Systematic Reviews, 7-Feb-2011
Tiaprofenic acid is a a non-steroidal anti-inflammatory drug (NSAID). It is widely available around the world, with indications for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, periarticular disorders, and strains and sprains. This review
- Single versus combination intravenous antibiotic therapy for people with cystic fibrosis
Cochrane Systematic Reviews, 29-Apr-2014
Choice of antibiotic, and the use of single or combined therapy are controversial areas in the treatment of respiratory infection in cystic fibrosis (CF). Advantages of combination therapy include wider range of modes of action, possible synergy and reduc
- Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne
Cochrane Systematic Reviews, 15-Mar-2011
Hirsutism is the presence of excessive hair growth in women and is an important cosmetic condition often resulting in severe distress. The most common cause is by increased production of male sex hormones (androgens). It is also affected by increased sens
- Statins and fibrates for preventing melanoma
Cochrane Systematic Reviews, 17-Nov-2014
Effective treatment for advanced melanoma is lacking. While no drug therapy currently exists for prevention of melanoma, in vitro, case-control, and animal model evidence suggest that lipid-lowering medications, commonly taken for high cholesterol, might
- Statins for the prevention of dementia
Cochrane Systematic Reviews, 4-Jan-2016
This is an update of a Cochrane review first published in 2001 and then updated in 2009. Vascular risk factors including high cholesterol levels increase the risk of dementia due to Alzheimer's disease and of vascular dementia. Some observational studies
- Steroid hormones for contraception in men
Cochrane Systematic Reviews, 10-Feb-2012
Male hormonal contraception has been an elusive goal. Administration of sex steroids to men can shut off sperm production through effects on the pituitary and hypothalamus. However, this approach also decreases production of testosterone, so 'add-back' th
- Steroid sex hormones for lower limb atherosclerosis
Cochrane Systematic Reviews, 19-Sep-2012
There is accumulating evidence that steroid sex hormones have a beneficial effect on a number of risk factors for peripheral arterial disease.
- Steroids for acute spinal cord injury
Cochrane Systematic Reviews, 12-Sep-2012
Acute spinal cord injury is a devastating condition typically affecting young people, mostly males. Steroid treatment in the early hours after the injury is aimed at reducing the extent of permanent paralysis during the rest of the patient's life.
- Steroids for idiopathic sudden sensorineural hearing loss
Cochrane Systematic Reviews, 18-Jun-2013
This is an update of a Cochrane review first published in The Cochrane Library in Issue 1, 2006 and previously updated in 2009.
- Steroids for improving recovery following tonsillectomy in children
Cochrane Systematic Reviews, 5-Jul-2011
This is an update of a Cochrane Review first published in The Cochrane Library in Issue 1, 2003.
- Steroids for symptom control in infectious mononucleosis
Cochrane Systematic Reviews, 7-Dec-2015
Infectious mononucleosis, also known as glandular fever or the kissing disease, is a benign lymphoproliferative disorder. It is a viral infection caused by the Epstein-Barr virus (EBV), a ubiquitous herpes virus that is found in all human societies and cu
- Steroids for traumatic optic neuropathy
Cochrane Systematic Reviews, 12-Jun-2013
Traumatic optic neuropathy (TON) is an important cause of severe visual loss following blunt or penetrating head trauma. Following the initial injury, optic nerve swelling within the optic nerve canal can result in secondary retinal ganglion cell loss. Op
- Steroids for treating cerebral malaria
Cochrane Systematic Reviews, 17-Feb-2009
Cerebral malaria is associated with swelling of the brain. Corticosteroid drugs could reduce the harmful effects of this swelling, but they could also suppress host immunity to infection.