- Rituximab for people with multiple sclerosis
Cochrane Systematic Reviews, 8-Nov-2021
Multiple sclerosis (MS) is the most common neurological cause of disability in young adults. Off-label rituximab for MS is used in most countries surveyed by the International Federation of MS, including high-income countries where on-label disease-modify - Rituximab for relapsing-remitting multiple sclerosis
Cochrane Systematic Reviews, 5-Dec-2013
This is an update of the Cochrane review "Rituximab for relapsing-remitting multiple sclerosis" (first published in The Cochrane Library 2011, Issue 12). - Rituximab for rheumatoid arthritis
Cochrane Systematic Reviews, 25-Nov-2014
Rituximab is a selective, B-cell depleting, biologic agent for treating refractory rheumatoid arthritis (RA). It is a chimeric monoclonal antibody targeted against CD 20 that is promoted as therapy for patients who fail to respond to other biologics. Ther - Rituximab for thyroid-associated ophthalmopathy
Cochrane Systematic Reviews, 29-Apr-2013
Thyroid associated ophthalmopathy (TAO) is the most frequent extrathyroidal manifestation of Graves' disease, affecting up to 50% of patients, and has a great impact on quality of life. Rituximab is a human/murine chimeric monoclonal antibody that targets - Rituximab for treating inhibitors in people with inherited severe hemophilia
Cochrane Systematic Reviews, 3-Aug-2020
Hemophilia A and B are inherited coagulation disorders characterized by a reduced or absent level of factor VIII or factor IX respectively. The severe form is characterized by a factor level less than 0.01 international units (IU) per milliliter. The deve - Rituximab, ofatumumab and other monoclonal anti-CD20 antibodies for chronic lymphocytic leukaemia
Cochrane Systematic Reviews, 14-Nov-2012
Chronic lymphocytic leukaemia (CLL) accounts for 25% of all leukaemias and is the most common lymphoid malignancy in western countries. Standard treatments include mono- or polychemotherapies, usually combined with monoclonal antibodies such as rituximab - Rivastigmine for Alzheimer's disease
Cochrane Systematic Reviews, 22-Sep-2015
Alzheimer's disease is the commonest cause of dementia affecting older people. One of the therapeutic strategies aimed at ameliorating the clinical manifestations of Alzheimer's disease is to enhance cholinergic neurotransmission in the brain by the use o - Rivastigmine for dementia in people with Down syndrome
Cochrane Systematic Reviews, 21-Jan-2009
Alzheimer's dementia (AD) is the most common form of dementia in people with Down Syndrome (DS). Acetylcholine is a chemical found in the brain that has an important role in memory, attention, reason and language. Rivastigmine is a “pseudo-irreversible” i - Rivastigmine for vascular cognitive impairment
Cochrane Systematic Reviews, 31-May-2013
Vascular dementia represents the second most common type of dementia after Alzheimer's disease. In older patients, in particular, the combination of vascular dementia and Alzheimer's disease is common, and is referred to as mixed dementia. The classificat - Rizatriptan for acute migraine
Cochrane Systematic Reviews, 10-Jun-2019
There are a number of different drug treatments for acute migraine, including currently four triptans, with several more likely to become available in the future. There is a need for evidence-based information to help determine the balance of benefit and - Robot assistant versus human or another robot assistant in patients undergoing laparoscopic cholecystectomy
Cochrane Systematic Reviews, 12-Sep-2012
The role of a robotic assistant in laparoscopic cholecystectomy is controversial. While some trials have shown distinct advantages of a robotic assistant over a human assistant others have not, and it is unclear which robotic assistant is best. - Robot‐assisted surgery in gynaecology
Cochrane Systematic Reviews, 15-Apr-2019
This is an updated merged review of two originally separate Cochrane reviews: one on robot-assisted surgery (RAS) for benign gynaecological disease, the other on RAS for gynaecological cancer. RAS is a relatively new innovation in laparoscopic surgery tha - Robotic assisted surgery for gynaecological cancer
Cochrane Systematic Reviews, 25-Apr-2019
Robotic surgery is the latest innovation in the field of minimally invasive surgery. Robotic surgical systems have been used to perform surgery for endometrial, cervical cancer and ovarian cancer. There is mounting evidence which demonstrates the feasibil - Robotic surgery for benign gynaecological disease
Cochrane Systematic Reviews, 25-Apr-2019
Robotic surgery is the latest innovation in the field of minimally invasive surgery. In the case of robotic surgery, instead of directly moving the instruments the surgeon uses a robotic system to control the instruments for surgical procedures. Robotic s - Robotic versus open radical cystectomy for bladder cancer in adults
Cochrane Systematic Reviews, 24-Apr-2019
It has been suggested that in comparison with open radical cystectomy, robotic-assisted radical cystectomy results in less blood loss, shorter convalescence, and fewer complications with equivalent short-term oncological and functional outcomes; however, - Rocuronium versus succinylcholine for rapid sequence induction intubation
Cochrane Systematic Reviews, 29-Oct-2015
Patients often require a rapid sequence induction (RSI) endotracheal intubation technique during emergencies or electively to protect against aspiration, increased intracranial pressure, or to facilitate intubation. Traditionally succinylcholine has been - Rofecoxib for osteoarthritis
Cochrane Systematic Reviews, 13-Jun-2008
Editor's note: The anti-inflammatory drug rofecoxib (Vioxx) was withdrawn from the market at the end of September 2004 after it was shown that long-term use (greater than 18 months) could increase the risk of heart attack and stroke. Further information i - Rofecoxib for rheumatoid arthritis
Cochrane Systematic Reviews, 24-Jan-2005
Editor's note: The anti-inflammatory drug rofecoxib (Vioxx) was withdrawn from the market at the end of September 2004 after it was shown that long-term use (greater than 18 months) could increase the risk of heart attack and stroke. Further information i - Role of chemotherapy additional to high-dose methotrexate for primary central nervous system lymphoma (PCNSL)
Cochrane Systematic Reviews, 26-Sep-2012
Primary central nervous system lymphoma (PCNSL) is a variant of extranodal non-Hodgkin lymphoma (NHL) that accounts for about 2% to 5% of all primary intracranial tumours with immunocompetent patients. It appears at a median age of 62 years. A standard of - Rooming‐in for new mother and infant versus separate care for increasing the duration of breastfeeding
Cochrane Systematic Reviews, 26-Aug-2016
Mother-infant proximity and interactions after birth and during the early postpartum period are important for breast-milk production and breastfeeding success. Rooming-in and separate care are both traditional practices. Rooming-in involves keeping the mo
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