Showing 681-700 of 746 for: Cochrane Systematic Reviews > Pharmacotherapeutics 
- Surgical implantation of steroids with antiangiogenic characteristics for treating neovascular age‐related macular degeneration
Cochrane Systematic Reviews, 31-Jan-2013
Neovascular age-related macular degeneration (AMD) is associated with rapid vision loss due to choroidal neovascularization (CNV), leakage, and scarring. Steroids have gained attention in their role for the treatment of neovascular AMD for their antiangio
- Surgical interventions for the rheumatoid shoulder
Cochrane Systematic Reviews, 20-Jan-2010
Involvment of the shoulder joint in patients with rheumatoid arthritis (RA) leads to severe destruction of the glenohumeral joint. When conservative treatment does not result in sufficient improvement, surgical procedures may be considered as the only ben
- Surgical versus non-surgical management of pleural empyema
Cochrane Systematic Reviews, 21-Jul-2009
Pleural empyema is a collection of pus between the lungs and the chest wall. There is debate about treatment options with the advent of both fibrinolytic enzymes to facilitate tube drainage and less invasive video-assisted thoracoscopic surgery (VATS).
- Sustained‐Release Naltrexone For Opioid Dependence
Cochrane Systematic Reviews, 23-Apr-2008
Naltrexone is an opioid antagonist which effectively blocks heroin effects. Since opioid dependence treatment with naltrexone tablets suffers from high dropout rates, several depot injections and implants are under investigation. Sustained-release formula
- Symptomatic treatment of the cough in whooping cough
Cochrane Systematic Reviews, 22-Sep-2014
Around 16 million cases of whooping cough (pertussis) occur worldwide each year, mostly in low-income countries. Much of the morbidity of whooping cough in children and adults is due to the effects of the paroxysmal cough. Cough treatments proposed includ
- Systemic antifungal therapy for tinea capitis in children
Cochrane Systematic Reviews, 12-May-2016
Tinea capitis is a common contagious fungal infection of the scalp in children. Systemic therapy is required for treatment and to prevent spread. This is an update of the original Cochrane review.
- Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 28-Aug-2014
Acute exacerbations of chronic obstructive pulmonary disease (COPD) are a major cause of hospital admission and mortality. They contribute to long-term decline in lung function, physical capacity and quality of life. The most common causes are infective,
- Systemic corticosteroids for acute gout
Cochrane Systematic Reviews, 23-Apr-2008
Gout is one of the most frequently occurring rheumatic diseases, worldwide. Given the well-known drawbacks of the regular treatments for acute gout (non-steroidal anti-inflammatory drugs (NSAIDs), colchicine), systemic corticosteroids might be safe altern
- Systemic therapy for treating locoregional recurrence in women with breast cancer
Cochrane Systematic Reviews, 23-Oct-2001
Between 10% and 35% of women with operable breast cancer will experience an isolated locoregional recurrence following their primary treatment. There is currently no good evidence that adjuvant systemic treatment is effective in this situation and there i
- Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults
Cochrane Systematic Reviews, 7-Oct-2009
The measurement of severity and control of asthma in both children and adults can be based on subjective or objective measures. It has been advocated that fractional exhaled nitric oxide (FeNO) can be used to monitor airway inflammation as it correlates w
- Tamoxifen for early breast cancer
Cochrane Systematic Reviews, 5-Aug-2008
There have been many randomised trials of adjuvant tamoxifen among women with early breast cancer, and an updated overview of their results is presented.
- Taxane‐containing regimens for metastatic breast cancer
Cochrane Systematic Reviews, 10-Jun-2015
It is generally accepted that taxanes are among the most active chemotherapy agents in the management of metastatic breast cancer. This is an update of a Cochrane review first published in 2003.
- Teicoplanin versus vancomycin for proven or suspected infection
Cochrane Systematic Reviews, 10-May-2010
Vancomycin and teicoplanin are commonly used to treat gram-positive infections, particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA). There is uncertainty regarding the effects of teicoplanin compared to vancomycin on kidney fun
- Testosterone for peri and postmenopausal women
Cochrane Systematic Reviews, 3-May-2010
The question of whether adding testosterone therapy to conventional postmenopausal hormone therapy (HT) is effective or safe is unresolved. Therefore, we aimed to determine the efficacy and safety of testosterone therapy for postmenopausal women using HT.
- Theophylline, aminophylline, caffeine and analogues for acute ischaemic stroke
Cochrane Systematic Reviews, 19-Jul-2004
Theophylline causes potent cerebral vasoconstriction which decreases blood flow in the non-ischaemic areas of the brain and increases collateral blood flow surrounding the ischaemic region. NOTE: This review covers an area where no active research is taki
- Therapeutic monitoring of antiepileptic drugs for epilepsy
Cochrane Systematic Reviews, 13-Apr-2010
This is an updated version of the original Cochrane review published in Issue 1, 2007.
- Therapies for depression in Parkinson's disease
Cochrane Systematic Reviews, 22-Apr-2003
Depression is one of the most common neuropsychiatric disturbances in Parkinson's disease. 40% of observed variation in quality of life is due to depression. However, there is little hard evidence of the efficacy and safety of antidepressant therapies in
- Thienopyridine derivatives versus aspirin for preventing stroke and other serious vascular events in high vascular risk patients
Cochrane Systematic Reviews, 7-Oct-2009
Aspirin is the most widely studied and prescribed antiplatelet agent for preventing serious vascular events, reducing the odds of such events among high vascular risk patients by about a quarter. Thienopyridine derivatives inhibit platelet activation by a
- Thioridazine for schizophrenia
Cochrane Systematic Reviews, 12-Apr-2011
Thioridazine is an antipsychotic that can still be used for schizophrenia although it is associated with the cardiac arrhythmia, torsades de pointe.
- Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis
Cochrane Systematic Reviews, 26-May-2013
Antibiotic therapy for suspected acute bacterial meningitis (ABM) needs to be started immediately, even before the results of cerebrospinal fluid (CSF) culture and antibiotic sensitivity are available. Immediate commencement of effective treatment using t
