Showing 681-700 of 753 for: Cochrane Systematic Reviews > Pharmacotherapeutics 
- Steroids, radiotherapy, chemotherapy and stents for superior vena caval obstruction in carcinoma of the bronchus
Cochrane Systematic Reviews, 9-Mar-2015
Superior vena caval obstruction (SVCO) is an uncommon manifestation of carcinoma of the bronchus characterised by neck swelling and distended veins over the chest. Treatment options include radiotherapy, chemotherapy, steroids and insertion of an expandab
- Stimulant laxatives for constipation and soiling in children
Cochrane Systematic Reviews, 16-Jun-2008
Constipation is extremely common in childhood and may lead to overflow soiling/encopresis. Standard treatment of the more severe case is to empty the bowels of impacted faeces by the use of oral or rectal laxatives and then maintain regular bowel movement
- Strategies for managing sexual dysfunction induced by antidepressant medication
Cochrane Systematic Reviews, 16-Apr-2013
Sexual dysfunction (including altered sexual desire, orgasmic and ejaculatory dysfunction, erectile and other problems) is a relatively common side effect of antidepressant medication. These sexual side effects may compromise a person's lifestyle and resu
- Sulpiride for schizophrenia
Cochrane Systematic Reviews, 17-Oct-2012
The antipsychotic drug sulpiride was formulated over 20 years ago and was marked as having a low incidence of adverse effects and an effect on the negative symptoms of schizophrenia. This relatively inexpensive antipsychotic drug has a similar neuropharma
- Supportive care for patients with gastrointestinal cancer
Cochrane Systematic Reviews, 6-Oct-2009
This review is an update of a previously published update review in The Cochrane Database of Systematic Reviews (Issue 4, 2006) on this topic. No new studies have been identified from the update search and the conclusions are not altered. Supportive care
- Surgery versus primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus)
Cochrane Systematic Reviews, 18-May-2014
Several studies have evaluated the clinical effectiveness of endocrine therapy alone in women aged 70 years or over with operable breast cancer and who are fit for surgery.
- Surgery versus thrombolysis for initial management of acute limb ischaemia
Cochrane Systematic Reviews, 23-May-2013
Peripheral arterial thrombolysis is technique used in the management of peripheral arterial ischaemia. Much is known about the indications, risks and benefits of thrombolysis. However, it is not known whether thrombolysis works better than surgery in the
- Surgical implantation of steroids with antiangiogenic characteristics for treating neovascular age-related macular degeneration
Cochrane Systematic Reviews, 7-Dec-2012
Neovascular age-related macular degeneration (AMD) is associated with rapid vision loss due to choroidal neovascularization (CNV), leakage, and scarring. Steroids have gained attention in their role for the treatment of neovascular AMD for their antiangio
- Surgical interventions for the rheumatoid shoulder
Cochrane Systematic Reviews, 11-Nov-2009
Involvment of the shoulder joint in patients with rheumatoid arthritis (RA) leads to severe destruction of the glenohumeral joint. When conservative treatment does not result in sufficient improvement, surgical procedures may be considered as the only ben
- Surgical versus non-surgical management of pleural empyema
Cochrane Systematic Reviews, 21-Jul-2009
Pleural empyema is a collection of pus between the lungs and the chest wall. There is debate about treatment options with the advent of both fibrinolytic enzymes to facilitate tube drainage and less invasive video-assisted thoracoscopic surgery (VATS).
- Sustained-Release Naltrexone For Opioid Dependence
Cochrane Systematic Reviews, 26-Mar-2008
Naltrexone is an opioid antagonist which effectively blocks heroin effects. Since opioid dependence treatment with naltrexone tablets suffers from high dropout rates, several depot injections and implants are under investigation. Sustained-release formula
- Symptomatic treatment of the cough in whooping cough
Cochrane Systematic Reviews, 22-Sep-2014
Around 16 million cases of whooping cough (pertussis) occur worldwide each year, mostly in low-income countries. Much of the morbidity of whooping cough in children and adults is due to the effects of the paroxysmal cough. Cough treatments proposed includ
- Systemic antifungal therapy for tinea capitis in children
Cochrane Systematic Reviews, 20-Jun-2012
Tinea capitis is a common contagious fungal infection of the scalp in children. Systemic therapy is required for treatment and to prevent spread.
- Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 28-Aug-2014
Acute exacerbations of chronic obstructive pulmonary disease (COPD) are a major cause of hospital admission and mortality. They contribute to long-term decline in lung function, physical capacity and quality of life. The most common causes are infective,
- Systemic corticosteroids for acute gout
Cochrane Systematic Reviews, 12-Aug-2008
Gout is one of the most frequently occurring rheumatic diseases, worldwide. Given the well-known drawbacks of the regular treatments for acute gout (non-steroidal anti-inflammatory drugs (NSAIDs), colchicine), systemic corticosteroids might be safe altern
- Systemic therapy for treating locoregional recurrence in women with breast cancer
Cochrane Systematic Reviews, 10-Jun-2008
Between 10% and 35% of women with operable breast cancer will experience an isolated locoregional recurrence following their primary treatment. There is currently no good evidence that adjuvant systemic treatment is effective in this situation and there i
- Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults
Cochrane Systematic Reviews, 11-Aug-2009
The measurement of severity and control of asthma in both children and adults can be based on subjective or objective measures. It has been advocated that fractional exhaled nitric oxide (FeNO) can be used to monitor airway inflammation as it correlates w
- Tamoxifen for early breast cancer
Cochrane Systematic Reviews, 5-Aug-2008
There have been many randomised trials of adjuvant tamoxifen among women with early breast cancer, and an updated overview of their results is presented.
- Taxane-containing regimens for metastatic breast cancer
Cochrane Systematic Reviews, 11-Jun-2015
It is generally accepted that taxanes are among the most active chemotherapy agents in the management of metastatic breast cancer. This is an update of a Cochrane review first published in 2003.
- Teicoplanin versus vancomycin for proven or suspected infection
Cochrane Systematic Reviews, 10-May-2010
Vancomycin and teicoplanin are commonly used to treat gram-positive infections, particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA). There is uncertainty regarding the effects of teicoplanin compared to vancomycin on kidney fun
