Showing 7081-7100 of 8668 for: Cochrane Systematic Reviews Back
- Secondary suturing compared to non-suturing for broken down perineal wounds following childbirth
Cochrane Systematic Reviews, 23-Sep-2013
Each year approximately 350,000 women in the United Kingdom and millions more worldwide, experience perineal suturing following childbirth. The postpartum management of perineal trauma is a core component of routine maternity care. However, for those wome
- Second-generation antidepressants for preventing seasonal affective disorder in adults
Cochrane Systematic Reviews, 15-Apr-2019
Seasonal affective disorder (SAD) is a seasonal pattern of recurrent major depressive episodes that most commonly occurs during autumn or winter and remits in spring. The prevalence of SAD ranges from 1.5% to 9%, depending on latitude. The predictable sea
- Second‐generation antidepressants for treatment of seasonal affective disorder
Cochrane Systematic Reviews, 4-Mar-2021
Seasonal affective disorder (SAD) is a seasonal pattern of recurrent depressive episodes that is often treated with second-generation antidepressants (SGAs), light therapy, or psychotherapy.
- Second-generation antipsychotics for anxiety disorders
Cochrane Systematic Reviews, 26-Oct-2011
Anxiety disorders are common and disabling conditions, with a lifetime prevalence of 17% in the general population. Due to high rates of treatment resistance, there is interest in new pharmacological treatment options such as second-generation antipsychot
- Second-generation antipsychotics for major depressive disorder and dysthymia
Cochrane Systematic Reviews, 18-Jan-2012
Major depressive disorder (MDD) is a common condition with a lifetime prevalence of 15% to 18%, which leads to considerable suffering and disability. Some antipsychotics have been reported to induce remission in major depression, when added to an antidepr
- Second-generation antipsychotics for obsessive compulsive disorder
Cochrane Systematic Reviews, 10-Nov-2010
Obsessive compulsive disorder (OCD) is a psychiatric disorder which has been shown to affect 2 to 3.5% of people during their lifetimes. Inadequate response occurs in 40% to 60% of people that are prescribed first line pharmaceutical treatments (selective
- Second‐line chemotherapy for non‐small cell lung cancer
Cochrane Systematic Reviews, 22-Apr-2002
The role of second-line chemotherapy for the treatment of patients with non-small cell lung cancer (NSCLC) who have relapsed or failed to respond to first-line treatment was unclear.
- Second‐line systemic therapy for metastatic colorectal cancer
Cochrane Systematic Reviews, 27-Jan-2017
The therapeutic management of people with metastatic colorectal cancer (CRC) who did not respond to first-line treatment represents a formidable challenge.
- Sedation of children undergoing dental treatment
Cochrane Systematic Reviews, 17-Dec-2018
Children's fear about dental treatment may lead to behaviour management problems for the dentist, which can be a barrier to the successful dental treatment of children. Sedation can be used to relieve anxiety and manage behaviour in children undergoing de
- Sedation versus general anaesthesia for provision of dental treatment to patients younger than 18 years
Cochrane Systematic Reviews, 28-Sep-2015
A significant proportion of children have caries requiring restorations or extractions, and some of these children will not accept this treatment under local anaesthetic. Historically this has been managed by the use of a general anaesthetic in children;
- Sedative techniques for endoscopic retrograde cholangiopancreatography
Cochrane Systematic Reviews, 13-May-2012
Endoscopic retrograde cholangiopancreatography (ERCP) is an uncomfortable therapeutic procedure that cannot be performed without adequate sedation or general anaesthesia. A considerable number of ERCPs are performed annually in the UK (at least 48,000) an
- Sedatives for opioid withdrawal in newborn infants
Cochrane Systematic Reviews, 18-May-2021
Neonatal abstinence syndrome (NAS) due to opioid withdrawal may result in disruption of the mother–infant relationship, sleep–wake abnormalities, feeding difficulties, weight loss, seizures and neurodevelopmental problems.
- Selective computed tomography (CT) versus routine thoracoabdominal CT for high-energy blunt-trauma patients
Cochrane Systematic Reviews, 17-Dec-2013
Trauma is the fifth leading cause of death worldwide, and in people younger than 40 years of age, it is the leading cause of death. During the resuscitation of trauma patients at the emergency department, there are two different commonly used diagnostic s
- Selective estrogen receptor modulators (SERMs) for uterine leiomyomas
Cochrane Systematic Reviews, 17-Oct-2012
Uterine fibroids are benign tumours that arise from individual smooth muscle cells of the uterus. Selective estrogen receptor modulators (SERMs) are estrogen receptor (ER) ligands that act as estrogens in some tissues while blocking estrogen activity in o
- Selective internal radiation therapy for liver metastases from colorectal cancer
Cochrane Systematic Reviews, 7-Oct-2009
Liver metastases are often the dominant site of metastatic disease in colorectal cancer. Selective internal radiation therapy (SIRT) involves embolising radiolabeled spheres (SIR-Spheres) into the arterial supply of the liver with the aim of improving the
- Selective noradrenaline reuptake inhibitors for schizophrenia
Cochrane Systematic Reviews, 25-Jan-2018
Schizophrenia is frequently a chronic and disabling illness with a heterogeneous range of symptoms. The positive symptoms usually respond to antipsychotics but the cognitive and negative symptoms of schizophrenia are difficult to treat with conventional a
- Selective oestrogen receptor modulators (SERMs) for endometriosis
Cochrane Systematic Reviews, 11-May-2021
Endometriosis is defined as the presence of endometrial tissue outside the uterine cavity. This chronic and recurring condition occurs in women of reproductive age. It is a common cause of pain or infertility and can cause non-specific symptoms such as lo
- Selective progesterone receptor modulators (SPRMs) for uterine fibroids
Cochrane Systematic Reviews, 26-Apr-2017
Uterine fibroids are smooth muscle tumours arising from the uterus. These tumours, although benign, are commonly associated with abnormal uterine bleeding, bulk symptoms and reproductive dysfunction. The importance of progesterone in fibroid pathogenesis
- Selective serotonin reuptake inhibitors (SSRIs) and serotonin‐norepinephrine reuptake inhibitors (SNRIs) for the prevention of migraine in adults
Cochrane Systematic Reviews, 1-Apr-2015
This is an updated version of the original Cochrane review published in 2005 on selective serotonin reuptake inhibitors (SSRIs) for preventing migraine and tension-type headache. The original review has been split in two parts and this review now only reg
- Selective serotonin reuptake inhibitors (SSRIs) and serotonin‐norepinephrine reuptake inhibitors (SNRIs) for the prevention of tension‐type headache in adults
Cochrane Systematic Reviews, 1-May-2015
This is an updated version of the Cochrane review published in 2005 on selective serotonin re-uptake inhibitors (SSRIs) for preventing migraine and tension-type headache. The original review has been split in two parts and this review now only regards ten
