Showing 701-720 of 753 for: Cochrane Systematic Reviews > Pharmacotherapeutics 
- Testosterone for peri and postmenopausal women
Cochrane Systematic Reviews, 3-May-2010
The question of whether adding testosterone therapy to conventional postmenopausal hormone therapy (HT) is effective or safe is unresolved. Therefore, we aimed to determine the efficacy and safety of testosterone therapy for postmenopausal women using HT.
- The effect of pharmacist-provided non-dispensing services on patient outcomes, health service utilisation and costs in low- and middle-income countries
Cochrane Systematic Reviews, 28-Jan-2013
The role of pharmacists has expanded beyond dispensing and packaging over the past two decades, and now includes ensuring rational use of drugs, improving clinical outcomes and promoting health status by working with the public and other healthcare profes
- Theophylline, aminophylline, caffeine and analogues for acute ischaemic stroke
Cochrane Systematic Reviews, 7-Oct-2008
Theophylline causes potent cerebral vasoconstriction which decreases blood flow in the non-ischaemic areas of the brain and increases collateral blood flow surrounding the ischaemic region. NOTE: This review covers an area where no active research is taki
- Therapeutic monitoring of antiepileptic drugs for epilepsy
Cochrane Systematic Reviews, 13-Apr-2010
This is an updated version of the original Cochrane review published in Issue 1, 2007.
- Therapies for depression in Parkinson's disease
Cochrane Systematic Reviews, 12-Nov-2008
Depression is one of the most common neuropsychiatric disturbances in Parkinson's disease. 40% of observed variation in quality of life is due to depression. However, there is little hard evidence of the efficacy and safety of antidepressant therapies in
- Thienopyridine derivatives versus aspirin for preventing stroke and other serious vascular events in high vascular risk patients
Cochrane Systematic Reviews, 11-Aug-2009
Aspirin is the most widely studied and prescribed antiplatelet agent for preventing serious vascular events, reducing the odds of such events among high vascular risk patients by about a quarter. Thienopyridine derivatives inhibit platelet activation by a
- Thioridazine for schizophrenia
Cochrane Systematic Reviews, 12-Apr-2011
Thioridazine is an antipsychotic that can still be used for schizophrenia although it is associated with the cardiac arrhythmia, torsades de pointe.
- Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis
Cochrane Systematic Reviews, 26-May-2013
Antibiotic therapy for suspected acute bacterial meningitis (ABM) needs to be started immediately, even before the results of cerebrospinal fluid (CSF) culture and antibiotic sensitivity are available. Immediate commencement of effective treatment using t
- Thrombolysis (different doses, routes of administration and agents) for acute ischaemic stroke
Cochrane Systematic Reviews, 2-Apr-2013
Stroke is a leading cause of death and disability world wide. Thrombolysis with recombinant tissue plasminogen activator (rt-PA) is licensed for treatment of acute ischaemic stroke in the early hours after symptom onset. It has been shown in randomised co
- Thrombolysis for acute deep vein thrombosis
Cochrane Systematic Reviews, 22-Jan-2014
Standard treatment for deep vein thrombosis aims to reduce immediate complications. Use of thrombolysis or clot dissolving drugs could reduce the long-term complications of post-thrombotic syndrome (PTS) (pain, swelling, skin discolouration, or venous ulc
- Thrombolysis for acute ischaemic stroke
Cochrane Systematic Reviews, 29-Jul-2014
Most strokes are due to blockage of an artery in the brain by a blood clot. Prompt treatment with thrombolytic drugs can restore blood flow before major brain damage has occurred and improve recovery after stroke in some people. Thrombolytic drugs, howeve
- Thrombolysis for cerebral vein and dural sinus thrombosis
Cochrane Systematic Reviews, 13-Oct-2008
Treatment of cerebral sinus thrombosis with thrombolytics has been reported in cases with a deteriorating clinical course despite anticoagulant therapy. The rationale of this treatment is to promote rapid recanalisation of the occluded sinus.
- Thrombolytic agents for arterial and venous thromboses in neonates
Cochrane Systematic Reviews, 21-Oct-2008
Clinically symptomatic thromboses are infrequent but serious complications in infants undergoing intensive care. Most are related to central vascular catheters. Symptomatic thrombosis may cause severe morbidity due to irreversible organ damage and also lo
- Thrombolytic therapy for pulmonary embolism
Cochrane Systematic Reviews, 15-Apr-2021
Thrombolytic therapy is usually reserved for people with clinically serious or massive pulmonary embolism (PE). Evidence suggests that thrombolytic agents may dissolve blood clots more rapidly than heparin and may reduce the death rate associated with PE.
- Thyrotropin-releasing hormone added to corticosteroids for women at risk of preterm birth for preventing neonatal respiratory disease
Cochrane Systematic Reviews, 19-Nov-2013
Thyrotropin-releasing hormones (TRH) added to prenatal corticosteroids has been suggested as a way to further reduce breathing problems and neonatal lung disease in infants born preterm.
- Tiotropium for stable chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 21-Nov-2012
Tiotropium is a new anticholinergic therapy for chronic obstructive pulmonary disease (COPD) that differs from ipratropium by its functional relative selectivity for muscarinic receptor subtypes and which allows once-per-day dosing.
- Topical agents and dressings for fungating wounds
Cochrane Systematic Reviews, 14-May-2014
Fungating wounds arise from primary, secondary or recurrent malignant disease and are associated with advanced cancer. A small proportion of patients may achieve healing following surgical excision, but treatment is usually palliative. Fungating wound man
- Topical corticosteroids as adjunctive therapy for bacterial keratitis
Cochrane Systematic Reviews, 15-Oct-2014
Bacterial keratitis is a serious ocular infectious disease that can lead to severe visual disability. Risk factors for bacterial corneal infection include contact lens wear, ocular surface disease, corneal trauma, and previous ocular or eyelid surgery. To
- Topical nasal steroids for intermittent and persistent allergic rhinitis in children
Cochrane Systematic Reviews, 10-Nov-2008
Allergic rhinitis is a very common chronic illness affecting 10% to 40% of children worldwide. There has been a significant increase in prevalence among children over the last two decades and this increase has been accompanied by a parallel increase in co
- Topical pimecrolimus for eczema
Cochrane Systematic Reviews, 22-Mar-2009
Pimecrolimus was developed as an alternative to topical corticosteroids for treating eczema (atopic dermatitis) but its efficacy and safety compared with existing treatments remains unclear.
