- Sensory environment on health-related outcomes of hospital patients
Cochrane Systematic Reviews, 15-Feb-2012
Hospital environments have recently received renewed interest, with considerable investments into building and renovating healthcare estates. Understanding the effectiveness of environmental interventions is important for resource utilisation and providin - Sensory stimulation for brain injured individuals in coma or vegetative state
Cochrane Systematic Reviews, 22-Apr-2002
Coma and vegetative state follow traumatic brain injury in about one out of eight patients, and in patients with non traumatic injury the prognosis is worse. The use of sensory stimulation for coma and vegetative state has gained popularity during the 198 - Sentinel lymph node biopsy followed by lymph node dissection for localised primary cutaneous melanoma
Cochrane Systematic Reviews, 16-May-2015
Melanoma is the leading cause of skin cancer-associated mortality. The vast majority of newly diagnosed melanomas are confined to the primary cutaneous site. Surgery represents the mainstay of melanoma treatment. Treatment strategies include wide excision - Sentinel node assessment for diagnosis of groin lymph node involvement in vulval cancer
Cochrane Systematic Reviews, 27-Jun-2014
Vulval cancer is usually treated by wide local excision with removal of groin lymph nodes (inguinofemoral lymphadenectomy) from one or both sides, depending on the tumour location. However, this procedure is associated with significant morbidity. As lymph - Sentinel node biopsy for diagnosis of lymph node involvement in endometrial cancer
Cochrane Systematic Reviews, 9-Jun-2021
Pelvic lymphadenectomy provides prognostic information for those diagnosed with endometrial (womb) cancer and provides information that may influence decisions regarding adjuvant treatment. However, studies have not shown a therapeutic benefit, and lympha - Septum resection for women of reproductive age with a septate uterus
Cochrane Systematic Reviews, 17-Jan-2017
Women with a septate uterus are at increased risk for subfertility, recurrent miscarriage, and preterm birth. Restoration of the anatomy of the uterus by hysteroscopic septum resection is an established intervention. This treatment has been assessed mainl - Sequencing of anthracyclines and taxanes in neoadjuvant and adjuvant therapy for early breast cancer
Cochrane Systematic Reviews, 18-Feb-2019
Anthracyclines and taxanes are chemotherapeutic agents widely used in a sequential regimen in the adjuvant and neoadjuvant treatment of early breast cancer to reduce the risk of cancer recurrence. Standard practice is to administer anthracycline-based che - Sequencing of chemotherapy and radiotherapy for early breast cancer
Cochrane Systematic Reviews, 30-Apr-2013
After surgery for localised breast cancer, radiotherapy (RT) improves both local control and breast cancer-specific survival. In patients at risk of harbouring micro-metastatic disease, adjuvant chemotherapy (CT) improves 15-year survival. However, the be - Sequential combination of glucocorticosteroids and alfa interferon versus alfa interferon alone for HBeAg‐positive chronic hepatitis B
Cochrane Systematic Reviews, 20-Jul-2005
Chronic hepatitis B has serious effects on morbidity and mortality. Alfa interferon has been shown to increase the rates of HBeAg-clearance as well as seroconversion to anti-HBe, but response rates are unsatisfactory. Glucocorticosteroid pretreatment may - Sequential inactivated (IPV) and live oral (OPV) poliovirus vaccines for preventing poliomyelitis
Cochrane Systematic Reviews, 5-Dec-2019
Poliomyelitis mainly affects unvaccinated children under five years of age, causing irreversible paralysis or even death. The oral polio vaccine (OPV) contains live attenuated virus, which can, in rare cases, cause a paralysis known as vaccine-associated - Sequential versus standard triple first‐line therapy for Helicobacter pylori eradication
Cochrane Systematic Reviews, 28-Jun-2016
Non-bismuth quadruple sequential therapy (SEQ) comprising a first induction phase with a dual regimen of amoxicillin and a proton pump inhibitor (PPI) for five days followed by a triple regimen phase with a PPI, clarithromycin and metronidazole for anothe - Serenoa repens for benign prostatic hyperplasia
Cochrane Systematic Reviews, 12-Dec-2012
Benign prostatic hyperplasia (BPH) is a nonmalignant enlargement of the prostate, which can lead to obstructive and irritative lower urinary tract symptoms (LUTS). The pharmacologic use of plants and herbs (phytotherapy) for the treatment of LUTS associat - Serotonin and noradrenaline reuptake inhibitors (SNRI) for stress urinary incontinence in adults
Cochrane Systematic Reviews, 5-Nov-2008
To date, standard recommendations for the management of stress urinary incontinence (SUI) would be either pelvic floor muscle training (PFMT) or surgery. A new form of drug treatment with a serotonin-noradrenaline reuptake inhibitor (SNRI), duloxetine, ma - Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia
Cochrane Systematic Reviews, 28-Feb-2018
Fibromyalgia is a clinically defined chronic condition of unknown etiology characterized by chronic widespread pain that often co-exists with sleep disturbances, cognitive dysfunction and fatigue. People with fibromyalgia often report high disability leve - Serotonin receptor antagonists for highly emetogenic chemotherapy in adults
Cochrane Systematic Reviews, 16-Feb-2016
Serotonin receptor antagonists (5-HT3 RAs) are used to control chemotherapy-induced emesis. Although they have the same general mechanism of action (blockade of serotonin receptors), they have different chemical structures and may have different effects. - Sertindole for schizophrenia
Cochrane Systematic Reviews, 20-Jul-2005
Sertindole is an atypical antipsychotic, which is thought to give a lower incidence of extrapyramidal side effects at clinically effective doses than typical antipsychotic drugs. In December 1998, Lundbeck Ltd., the manufacturers of sertindole, voluntaril - Sertindole versus other atypical antipsychotics for schizophrenia
Cochrane Systematic Reviews, 15-Apr-2009
In many countries of the industrialised world second generation (atypical) antipsychotics have become the first line drug treatment for people with schizophrenia. The question as to whether and, if so, how much the effects of the various second generation - Sertraline versus other antidepressive agents for depression
Cochrane Systematic Reviews, 14-Apr-2010
The National Institute for Health and Clinical Excellence clinical practice guideline on the treatment of depressive disorder recommended that selective serotonin reuptake inhibitors should be the first-line option when drug therapy is indicated for a dep - Serum amylase and lipase and urinary trypsinogen and amylase for diagnosis of acute pancreatitis
Cochrane Systematic Reviews, 21-Apr-2017
The treatment of people with acute abdominal pain differs if they have acute pancreatitis. It is important to know the diagnostic accuracy of serum amylase, serum lipase, urinary trypsinogen-2, and urinary amylase for the diagnosis of acute pancreatitis, - Serum C‐reactive protein, procalcitonin, and lactate dehydrogenase for the diagnosis of pancreatic necrosis
Cochrane Systematic Reviews, 21-Apr-2017
The treatment of people with pancreatic necrosis differs from that of people with oedematous pancreatitis. It is important to know the diagnostic accuracy of serum C-reactive protein (CRP), serum procalcitonin, and serum lactate dehydrogenase (LDH) as a t
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