Showing 721-740 of 746 for: Cochrane Systematic Reviews > Pharmacotherapeutics 
- Tricyclic drugs for depression in children and adolescents
Cochrane Systematic Reviews, 18-Jun-2013
There is a need to identify effective and safe treatments for depression in children and adolescents. While tricyclic drugs are effective in treating depression in adults, individual studies involving children and adolescents have been equivocal. Prescrib
- Trifluoperazine for schizophrenia
Cochrane Systematic Reviews, 26-Jan-2004
Trifluoperazine is an inexpensive accessible 'high potency' antipsychotic drug, widely used to treat schizophrenia or related psychoses.
- Troleandomycin as an oral corticosteroid sparing agent in stable asthma
Cochrane Systematic Reviews, 23-Oct-2000
Patients with chronic severe asthma are often dependent on the long term prescription of oral corticosteroids. The use of steroids is associated with serious side effects. Physicians treating such patients continue to search for alternative therapies that
- Unfractionated or low‐molecular weight heparin for induction of remission in ulcerative colitis
Cochrane Systematic Reviews, 5-Aug-2015
There are a limited number of treatment options for patients with ulcerative colitis (UC). An increased risk of thrombosis in UC coupled with an observation that UC patients being treated with anticoagulant therapy for thrombotic events had an improvement
- Valproate for schizophrenia
Cochrane Systematic Reviews, 24-Nov-2016
Many people with schizophrenia do not achieve a satisfactory treatment response with ordinary antipsychotic drug treatment. In these cases, various add-on medications are used, and valproate is one of these.
- Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder
Cochrane Systematic Reviews, 16-Oct-2013
Bipolar disorder is a recurrent illness that is amongst the top 30 causes of disability worldwide and is associated with significant healthcare costs. In the past, emphasis was placed solely on the treatment of acute episodes of bipolar disorder; recently
- Vancomycin for prophylaxis against sepsis in preterm neonates
Cochrane Systematic Reviews, 24-Jan-2000
Nosocomial, late onset, sepsis occurs in up to 50% of infants of less than 1000gm at birth. The most frequent organism isolated is coagulase negative staphylococcus (CoNS). A number of studies have evaluated the efficacy of prophylactic low dose vancomyci
- Vasoactive drugs for acute stroke
Cochrane Systematic Reviews, 7-Jul-2010
It is unclear whether blood pressure (BP) should be altered actively during the acute phase of stroke.
- Vasodilators and vasoactive substances for idiopathic sudden sensorineural hearing loss
Cochrane Systematic Reviews, 7-Oct-2009
Idiopathic sudden sensorineural hearing loss (ISSHL) is sudden hearing loss where clinical assessment fails to reveal a cause. The most widely used therapeutic agents for ISSHL are antivirals, steroids, hyperbaric oxygen, vasodilators and rheological/vaso
- Vasodilators for primary Raynaud's phenomenon
Cochrane Systematic Reviews, 17-May-2021
Numerous agents have been suggested for the symptomatic treatment of primary Raynaud's phenomenon. Apart from calcium channel blockers, which are considered to be the drugs of choice, evidence of the effects of alternative pharmacological treatments is li
- Vitamin D and vitamin D analogues for preventing fractures in post‐menopausal women and older men
Cochrane Systematic Reviews, 14-Apr-2014
Vitamin D and related compounds have been used to prevent osteoporotic fractures in older people. This is the third update of a Cochrane review first published in 1996.
- Vitamin E for Alzheimer's dementia and mild cognitive impairment
Cochrane Systematic Reviews, 18-Apr-2017
Vitamin E occurs naturally in the diet. It has several biological activities, including functioning as an antioxidant to scavenge toxic free radicals. Evidence that free radicals may contribute to the pathological processes behind cognitive impairment has
- Vitamin E for antipsychotic‐induced tardive dyskinesia
Cochrane Systematic Reviews, 17-Jan-2018
Antipsychotic (neuroleptic) medication is used extensively to treat people with chronic mental illnesses. Its use, however, is associated with adverse effects, including movement disorders such as tardive dyskinesia (TD) – a problem often seen as repetiti
- Vitamin E for intermittent claudication
Cochrane Systematic Reviews, 26-Jan-1998
It is thought that vitamin E may improve tolerance to intermittent claudication (i.e. pain caused by ischaemia in the muscles of the leg during exercise), thereby relieving the pain, through a variety of mechanisms.
- Vitamin E supplementation for prevention of morbidity and mortality in preterm infants
Cochrane Systematic Reviews, 20-Oct-2003
Treating very low birth weight (VLBW) infants with pharmacologic doses of vitamin E as an antioxidant agent has been proposed for preventing or limiting retinopathy of prematurity, intracranial hemorrhage, hemolytic anemia, and chronic lung disease. Howev
- Vitamin E supplementation in pregnancy
Cochrane Systematic Reviews, 7-Sep-2015
Vitamin E supplementation may help reduce the risk of pregnancy complications involving oxidative stress, such as pre-eclampsia. There is a need to evaluate the efficacy and safety of vitamin E supplementation in pregnancy.
- Vitamin K antagonists versus antiplatelet therapy after transient ischaemic attack or minor ischaemic stroke of presumed arterial origin
Cochrane Systematic Reviews, 12-Sep-2012
People who have had a transient ischaemic attack (TIA) or non-disabling ischaemic stroke have an annual risk of major vascular events of between 4% and 11%. Aspirin reduces this risk by 20% at most. Secondary prevention trials after myocardial infarction
- Vitamin supplementation for preventing miscarriage
Cochrane Systematic Reviews, 6-May-2016
Miscarriage is a common complication of pregnancy that can be caused by a wide range of factors. Poor dietary intake of vitamins has been associated with an increased risk of miscarriage, therefore supplementing women with vitamins either prior to or in e
- Vitamins for epilepsy
Cochrane Systematic Reviews, 10-Aug-2009
Vitamins have been reported to be effective in controlling certain types of seizures and to prevent some of the harmful effects of antiepileptic drugs (AEDs). In this review we will summarize evidence from randomized controlled trials.
- Written information about individual medicines for consumers
Cochrane Systematic Reviews, 15-Apr-2009
Medicines are the most common intervention in most health services. As with all treatments, those taking medicines need sufficient information: to enable them to take and use the medicines effectively, to understand the potential harms and benefits, and t
