Showing 7581-7600 of 8875 for: Cochrane Systematic Reviews Back
- Steam inhalation or humidified oxygen for acute bronchiolitis in children up to three years of age
Cochrane Systematic Reviews, 7-Dec-2010
Acute bronchiolitis is a common respiratory infection and a major cause of morbidity in young children. It is treated with bronchodilators (for example, salbutamol), corticosteroids or humidified air (steam inhalation or cool mist). Steam inhalation is pr
- Stem cell therapy for chronic ischaemic heart disease and congestive heart failure
Cochrane Systematic Reviews, 24-Dec-2016
A promising approach to the treatment of chronic ischaemic heart disease and congestive heart failure is the use of stem cells. The last decade has seen a plethora of randomised controlled trials developed worldwide, which have generated conflicting resul
- Stem cell therapy for dilated cardiomyopathy
Cochrane Systematic Reviews, 21-Jul-2021
Stem cell therapy (SCT) has been proposed as an alternative treatment for dilated cardiomyopathy (DCM), nonetheless its effectiveness remains debatable.
- Stem cell therapy for treatment of thromboangiitis obliterans (Buerger's disease)
Cochrane Systematic Reviews, 31-Oct-2018
Thromboangiitis obliterans, also known as Buerger's disease, is a non-atherosclerotic, segmental inflammatory pathology that most commonly affects the small- and medium-sized arteries, veins, and nerves in the upper and lower extremities. The etiology is
- Stem cell transplantation for induction of remission in medically refractory Crohn’s disease
Cochrane Systematic Reviews, 13-May-2022
Crohn's disease (CD) is an inflammatory bowel disease that causes inflammation and stricture, of any part of the mucosa and the gut wall. It forms skip lesions, sparing the areas in between the affected parts of the gastrointestinal tract. Crohn's disease
- Stem cell transplantation for ischemic stroke
Cochrane Systematic Reviews, 5-May-2019
Stroke is a leading cause of morbidity and mortality worldwide, with very large healthcare and social costs, and a strong demand for alternative therapeutic approaches. Preclinical studies have shown that stem cells transplanted into the brain can lead to
- Stem cell transplantation for systemic sclerosis
Cochrane Systematic Reviews, 29-Jul-2022
Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by systemic inflammation, fibrosis, vascular injury, reduced quality of life, and limited treatment options. Autologous hematopoietic stem cell transplantation (HSCT) has emerged as a
- Stem cell treatment for acute myocardial infarction
Cochrane Systematic Reviews, 30-Sep-2015
Cell transplantation offers a potential therapeutic approach to the repair and regeneration of damaged vascular and cardiac tissue after acute myocardial infarction (AMI). This has resulted in multiple randomised controlled trials (RCTs) across the world.
- Stem cell‐based interventions for the prevention and treatment of intraventricular haemorrhage and encephalopathy of prematurity in preterm infants
Cochrane Systematic Reviews, 15-Feb-2023
Germinal matrix-intraventricular haemorrhage (GMH-IVH) and encephalopathy of prematurity (EoP) remain substantial issues in neonatal intensive care units worldwide. Current therapies to prevent or treat these conditions are limited. Stem cell-based therap
- Stem cell‐based interventions for the prevention of morbidity and mortality following hypoxic‐ischaemic encephalopathy in newborn infants
Cochrane Systematic Reviews, 19-Aug-2020
Hypoxic-ischaemic encephalopathy (HIE) is a leading cause of mortality and long-term neurological sequelae, affecting thousands of children worldwide. Current therapies to treat HIE are limited to cooling. Stem cell-based therapies offer a potential thera
- Stent graft types for endovascular repair of abdominal aortic aneurysms
Cochrane Systematic Reviews, 24-Sep-2015
The UK prevalence of abdominal aortic aneurysm (AAA) is estimated at 4.9% in over 65-year olds. Progressive and unpredictable enlargement can lead to rupture. Endovascular repair of AAAs involves a stent graft system being introduced via the femoral arter
- Stent graft types for endovascular repair of thoracic aortic aneurysms
Cochrane Systematic Reviews, 24-Sep-2015
The UK prevalence of thoracic aneurysm is estimated at 10.4 per 100,000 person-years. Progressive and unpredictable enlargement can lead to rupture. Endovascular repair of thoracic aortic aneurysms involves a stent graft system being introduced via the fe
- Stent placement versus surgery for coarctation of the thoracic aorta
Cochrane Systematic Reviews, 3-Apr-2012
Coarctation of the aorta (CoA) accounts for 5% to 7% of congenital heart disease, with an incidence of 0.3 to 0.4 per 1000 live births. Surgery was the only choice of therapy for CoA until 1982 when balloon angioplasty became an available alternative for
- Stent placement versus surgical palliation for adults with malignant gastric outlet obstruction
Cochrane Systematic Reviews, 30-May-2018
Malignant gastric outlet obstruction is the clinical and pathological consequence of cancerous disease causing a mechanical obstruction to gastric emptying. It usually occurs when malignancy is at an advanced stage; therefore, people have a limited life e
- Stents for the prevention of pancreatic fistula following pancreaticoduodenectomy
Cochrane Systematic Reviews, 6-May-2016
Several studies have demonstrated that the use of pancreatic duct stents following pancreaticoduodenectomy is associated with a lower risk of pancreatic fistula. However, to date there is a lack of accord in the literature on whether the use of stents is
- Stepping down the dose of inhaled corticosteroids for adults with asthma
Cochrane Systematic Reviews, 1-Feb-2017
Asthma is a condition of the airways affecting more than 300 million adults and children worldwide. National and international guidelines recommend titrating up the dose of inhaled corticosteroids (ICS) to gain symptom control at the lowest possible dose
- Stereotactic radiotherapy for vestibular schwannoma
Cochrane Systematic Reviews, 15-Dec-2014
Vestibular schwannomas (acoustic neuromas) are common benign tumours that arise from the Schwann cells of the vestibular nerve. Management options include observation with neuroradiological follow-up, microsurgical resection and stereotactic radiotherapy.
- Steroid avoidance or withdrawal for kidney transplant recipients
Cochrane Systematic Reviews, 22-Aug-2016
Steroid-sparing strategies have been attempted in recent decades to avoid morbidity from long-term steroid intake among kidney transplant recipients. Previous systematic reviews of steroid withdrawal after kidney transplantation have shown a significant i
- Steroid avoidance or withdrawal for pancreas and pancreas with kidney transplant recipients
Cochrane Systematic Reviews, 12-Sep-2014
Pancreas or kidney-pancreas transplantation improves survival and quality of life for people with type 1 diabetes mellitus and kidney failure. Immunosuppression after transplantation is associated with complications. Steroids have adverse effects on cardi
- Steroid hormones for contraception in men
Cochrane Systematic Reviews, 14-Mar-2012
Male hormonal contraception has been an elusive goal. Administration of sex steroids to men can shut off sperm production through effects on the pituitary and hypothalamus. However, this approach also decreases production of testosterone, so 'add-back' th
