- Surfactant for bacterial pneumonia in late preterm and term infants
Cochrane Systematic Reviews, 11-Jan-2012
Pulmonary surfactant is an important part of the host defence against respiratory infections. Bacterial pneumonia in late preterm or term newborn infants often leads to surfactant deficiency or dysfunction, as surfactant is either inactivated or peroxidat - Surfactant for meconium aspiration syndrome in term and late preterm infants
Cochrane Systematic Reviews, 14-Dec-2014
Surfactant replacement therapy has been proven beneficial in the prevention and treatment of neonatal respiratory distress syndrome (RDS). The deficiency of surfactant or surfactant dysfunction may contribute to respiratory failure in a broader group of d - Surfactant for pulmonary haemorrhage in neonates
Cochrane Systematic Reviews, 3-Feb-2020
In the 1960s and 1970s, pulmonary haemorrhage (PH) occurred mainly in full-term infants with pre-existing illness with an incidence of 1.3 per 1000 live births. Risk factors for PH included severity of illness, intrauterine growth restriction, patent duct - Surfactant therapy for bronchiolitis in critically ill infants
Cochrane Systematic Reviews, 24-Aug-2015
Bronchiolitis is one of the most frequent causes of respiratory failure in infants; some infants will require intensive care and mechanical ventilation. There is lack of evidence regarding effective treatment for bronchiolitis other than supportive care. - Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome
Cochrane Systematic Reviews, 10-May-2021
Non-invasive respiratory support is increasingly used for the management of respiratory dysfunction in preterm infants. This approach runs the risk of under-treating those with respiratory distress syndrome (RDS), for whom surfactant administration is of - Surgery for cataracts in people with age‐related macular degeneration
Cochrane Systematic Reviews, 16-Feb-2017
Cataract and age-related macular degeneration (AMD) are common causes of decreased vision that often occur simultaneously in people over age 50. Although cataract surgery is an effective treatment for cataract-induced visual loss, some clinicians suspect - Surgery for cervical intraepithelial neoplasia
Cochrane Systematic Reviews, 4-Dec-2013
Cervical intraepithelial neoplasia (CIN) is the most common pre-malignant lesion. Atypical squamous changes occur in the transformation zone of the cervix with mild, moderate or severe changes described by their depth (CIN 1, 2 or 3). Cervical intraepithe - Surgery for cervical radiculopathy or myelopathy
Cochrane Systematic Reviews, 20-Jan-2010
Cervical spondylosis causes pain and disability by compressing the spinal cord or roots. Surgery to relieve the compression may reduce the pain and disability, but is associated with a small but definite risk. . - Surgery for chronic arthropathy in people with haemophilia
Cochrane Systematic Reviews, 30-Nov-2022
Chronic arthropathy is a potentially debilitating complication for people with haemophilia — a genetic, X-linked, recessive bleeding disorder, characterised by the absence or deficiency of a clotting factor protein. Staging classifications, such as the Ar - Surgery for complete (full‐thickness) rectal prolapse in adults
Cochrane Systematic Reviews, 24-Nov-2015
Complete (full-thickness) rectal prolapse is a lifestyle-altering disability that commonly affects older people. The range of surgical methods available to correct the underlying pelvic floor defects in full-thickness rectal prolapse reflects the lack of - Surgery for congenital choanal atresia
Cochrane Systematic Reviews, 15-Dec-2011
Congenital choanal atresia is a rare abnormality characterized by unilateral or bilateral lack of patency of the posterior end of the nasal cavity. With an incidence of 1:5000 to 1:8000 births, it is twice as prevalent in females as it is in males. Surgic - Surgery for deep venous insufficiency
Cochrane Systematic Reviews, 30-Sep-2021
Chronic deep venous insufficiency is caused by incompetent vein valves, blockage of large-calibre leg veins, or both; and causes a range of symptoms including recurrent ulcers, pain and swelling. Most surgeons accept that well-fitted graduated compression - Surgery for degenerative lumbar spondylosis
Cochrane Systematic Reviews, 19-Oct-2005
Surgical investigations and interventions account for large health care utilisation and costs, but the scientific evidence for most procedures is still limited. - Surgery for Dupuytren's contracture of the fingers
Cochrane Systematic Reviews, 9-Dec-2015
Dupuytren's disease is a benign fibroproliferative disorder that causes the fingers to be drawn into the palm via formation of new tissue under the glabrous skin of the hand. This disorder causes functional limitations, but it can be treated through a var - Surgery for epilepsy
Cochrane Systematic Reviews, 25-Jun-2019
This is an updated version of the original Cochrane review, published in 2015. - Surgery for faecal incontinence in adults
Cochrane Systematic Reviews, 2-Jul-2013
Faecal incontinence is a debilitating problem with significant medical, social and economic implications. Treatment options include conservative, non-operative interventions (for example pelvic floor muscle training, biofeedback, drugs) and surgical proce - Surgery for idiopathic epiretinal membrane
Cochrane Systematic Reviews, 24-Mar-2021
Epiretinal membrane is an abnormal sheet of avascular fibrocellular tissue that develops on the inner surface of the retina. Epiretinal membrane can cause impairment of sight as a consequence of progressive distortion of retinal architecture. - Surgery for lateral elbow pain
Cochrane Systematic Reviews, 16-Mar-2011
Surgery is sometimes recommended for persistent lateral elbow pain where other less invasive interventions have failed. - Surgery for limited‐stage small‐cell lung cancer
Cochrane Systematic Reviews, 21-Apr-2017
Current treatment guidelines for limited-stage small-cell lung cancer (SCLC) recommend concomitant platinum-based chemo-radiotherapy plus prophylactic cranial irradiation, based on the premise that SCLC disseminates early, and is chemosensitive. However, - Surgery for local and locally advanced non‐small cell lung cancer
Cochrane Systematic Reviews, 24-Jan-2005
Surgical resection (usually lobectomy) is considered the treatment of choice for many individuals with early stage non-small cell lung cancer (NSCLC) . However much of the evidence is observational.
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