Showing 61-80 of 374 for: Cochrane Systematic Reviews > Oncology 
- Chemotherapy for advanced, recurrent or metastatic endometrial carcinoma
Cochrane Systematic Reviews, 11-Feb-2015
Although endometrial adenocarcinoma is a common gynaecological cancer, a comparatively small proportion of patients present with, or develop, recurrent or advanced disease. However, for those women whose disease does progress or recur the prognosis is poo
- Chemotherapy for brain metastases from small cell lung cancer
Cochrane Systematic Reviews, 11-May-2012
Small cell lung cancer (SCLC) accounts for approximately 20% of all cases of lung cancer. It tends to disseminate early in the course of its natural history and to grow quickly. Approximately 10% to 18% of patients present with brain metastases (BM) at th
- Chemotherapy for high-grade glioma
Cochrane Systematic Reviews, 27-Mar-2014
Trials on the effect of systemic chemotherapy on survival and recurrence in adults with high-grade glioma have had inconclusive results. We undertook a systematic review and meta-analysis to assess the effects of such treatment on survival and recurrence.
- Chemotherapy for hormone-refractory prostate cancer
Cochrane Systematic Reviews, 2-Jun-2008
Prostate cancer mainly affects elderly men, and its incidence has steadily increased over the last decade. The management of this disease is replete with controversy. In men with advanced, metastatic prostate cancer, hormone therapy is almost universally
- Chemotherapy for malignant germ cell ovarian cancer in adult patients with early stage, advanced and recurrent disease
Cochrane Systematic Reviews, 14-Feb-2011
Malignant germ cell tumour of the ovary occurs in up to 0.07% of woman globally. Due to its rarity, evidence for treatment is lacking and often extrapolates clinical trial results of testicular germ cell cancers. The investigation on this rare tumour is f
- Chemotherapy for metastatic and recurrent cervical cancer
Cochrane Systematic Reviews, 27-Mar-2014
Cervical cancer is the second most common cancer among women up to 65 years of age and is the most frequent cause of death from gynaecological cancers worldwide. A woman's risk of developing cervical cancer by 65 years of age ranges from 0.69% in develope
- Chemotherapy for non-small cell lung cancer
Cochrane Systematic Reviews, 9-Mar-2015
The role of chemotherapy in the treatment of patients with non-small cell lung cancer was not clear. A systematic review and quantitative meta-analysis was therefore undertaken to evaluate the available evidence from all relevant randomised trials.
- Chemotherapy plus Rituximab versus chemotherapy alone for B-cell non-Hodgkin's lymphoma
Cochrane Systematic Reviews, 21-Aug-2008
Rituximab (R) has been shown to improve response rates and progression free survival when added to chemotherapy in patients with indolent and mantle cell lymphoma. However, the impact of R on overall survival (OS) when given in combination with chemothera
- Chemotherapy versus best supportive care for extensive small cell lung cancer
Cochrane Systematic Reviews, 22-Nov-2013
Combination chemotherapy has been the mainstay of treatment for extensive stage small celI lung cancer (SCLC) over the last 30 years, even though it only gives a short prolongation in median survival time. The main goal for these patients should be pallia
- Chemotherapy versus surgery for initial treatment in advanced ovarian epithelial cancer
Cochrane Systematic Reviews, 11-Feb-2015
Epithelial ovarian cancer presents at an advanced stage in the majority of women. These women require surgery and chemotherapy for optimal treatment. Conventional treatment is to perform surgery first and then give chemotherapy. However, it is not yet cle
- Chemotherapy, radiotherapy and combined modality for Hodgkin's disease, with emphasis on second cancer risk
Cochrane Systematic Reviews, 21-Aug-2008
Second malignancies (SM) are a major late effect of treatment for Hodgkin's disease (HD). Reliable comparisons of SM risk between alternative treatment strategies are lacking.
- Chinese herbal medicine for oesophageal cancer
Cochrane Systematic Reviews, 8-Jan-2016
Oesophageal cancer is the seventh leading cause of cancer death worldwide. Traditional Chinese herbal medicine is sometimes used as an adjunct to radiotherapy or chemotherapy for this type of cancer. This review was first published in 2007 and updated in
- Chinese medical herbs for chemotherapy side effects in colorectal cancer patients
Cochrane Systematic Reviews, 22-Jul-2008
Side effects, including nausea and vomiting, sore mouth , diarrhoea, hepatotoxicity, myelosuppression, and immunosuppression , are commonly encountered in patients with colorectal cancer who are treated with chemotherapy. A variety of Chinese herbal medic
- Chinese medicinal herbs to treat the side-effects of chemotherapy in breast cancer patients
Cochrane Systematic Reviews, 4-Sep-2008
Short term side-effects of chemotherapy include fatigue, nausea, vomiting, mucositis and myelosuppression or neutropenia. These occur during the course of treatment and generally resolve within months of completion of chemotherapy. A variety of Chinese me
- Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum
Cochrane Systematic Reviews, 23-Aug-2010
Although conventional colonoscopy is the most sensitive test available for the investigation of the colorectum for polyps, there are data that raise concerns about its sensitivity. Chromoscopy may be one way of enhancing the ability for colonoscopy to det
- Collection devices for obtaining cervical cytology samples
Cochrane Systematic Reviews, 11-Feb-2015
This review is no longer appropriate for update as liquid based cytology has superceded smear technology.
- Colony‐stimulating factors for chemotherapy‐induced febrile neutropenia
Cochrane Systematic Reviews, 30-Oct-2014
Febrile neutropenia is a frequent adverse event experienced by people with cancer who are undergoing chemotherapy, and is a potentially life-threatening situation. The current treatment is supportive care plus antibiotics. Colony-stimulating factors (CSFs
- Colony-stimulating factors for prevention of myelosuppressive therapy-induced febrile neutropenia in children with acute lymphoblastic leukaemia
Cochrane Systematic Reviews, 13-Mar-2012
Acute lymphoblastic leukaemia (ALL) is the most common cancer in childhood and febrile neutropenia is a potentially life-threatening side effect of its treatment. Current treatment consists of supportive care plus antibiotics. Clinical trials have attempt
- Colorectal stents for the management of malignant colonic obstructions
Cochrane Systematic Reviews, 3-Oct-2011
Colorectal cancer is one of the most common cancer in the western world. Acute colonic obstruction is one of the common presentations of colon cancer. Emergency surgical decompression is the traditional treatment of choice but is associated with high morb
- Combination chemotherapy for primary treatment of high-risk gestational trophoblastic tumour
Cochrane Systematic Reviews, 23-Mar-2016
This is an update of the original review that was published in The Cochrane Database of Systematic Reviews, 2009, Issue 2. Gestational trophoblastic neoplasia (GTN) are malignant disorders of the placenta that include invasive hydatidiform mole, choriocar
